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The map label for this gene is menB [H]

Identifier: 148242240

GI number: 148242240

Start: 1007644

End: 1008519

Strand: Direct

Name: menB [H]

Synonym: SynRCC307_1141

Alternate gene names: 148242240

Gene position: 1007644-1008519 (Clockwise)

Preceding gene: 148242239

Following gene: 148242241

Centisome position: 45.29

GC content: 62.33

Gene sequence:

>876_bases
ATGGTGGGAGCAGACACCAGCTCCTTGATGGCTGTGCCCGCCTACCCATGGATCCGTCAGGGCAACTACGACGACGTGCT
CTTCGAGCTGTCGGCTGATGAGGGGATTGCGCGCATCAGCATCAATCGACCTGAAAAACGCAATGCTTTTCGGCCTCGCA
CCGTCAGCGAGCTGTATGACGCCTTTGCCAGGGTGCGCGATAACCCCCGCATTGGCGTGGTGCTGTTCACCGGTGCCGGT
CCAGCGGCCGATGGTGCCTATGCCTTTTGCGCCGGTGGTGATCAGTCGGTGCGCGGCGATGGCGGCTACCTCGATGAGGA
GGGCACCCCGCGGCTGAATGTGCTCGACCTGCAGCGCTTGATCCGCAGCCTGCCGAAGGTGGTGATTGCCTTGGTGGCTG
GCTACGCCATTGGTGGCGGCCAGGTGTTGCATCTCCTTTGTGATCTGAGCATTGCGGCCGACAATGCTCAATTTGGTCAA
ACCGGTCCGCGGGTTGGCAGCTTTGATGGCGGCTATGGCTGCGCCCACCTCGCCCGGCTGGTGGGCCAGCGCAAGGCACG
CGAAATCTGGTTCCTCTGCCGCCGTTACAACGCTGAGCAAGCCTTGGCGATGGGGCTGGTGAACACGGTGGTTCCCCTCG
CTGAGCTCGAGAGTGAGGGCCTGTGCTGGGCGCGGGAGGTGCTGCAGCACAGCCCCACAGCGATCCGCTGTCTCAAAGCC
GCTTTCAACGCCGACACCGATGGCATGGCCGGATTGCAGGAATTGGCCGGGCAGGCCACCCATCTCTTCTACCGAACCGA
AGAGGGCCAAGAAGGACGCAATGCCTTCCTCGAAAAACGCGCTCCAGATTTCTCCGATCAGCCCTGGCTGCCTTAA

Upstream 100 bases:

>100_bases
TGCAGTGGTTGCTTGAGCCTGGTGATGCGATGCGCCTGCTGCGATGCTCCACCGACCGGTCCCGTGATGCCCAGCTGCGC
CAGCAGTTGCGTGACAAGCC

Downstream 100 bases:

>100_bases
ACCCTGAGAAATAAATAAAGCCTGATGAGTCCAGTGAGACGCACTGGCTAGCAGAAGGGGGAATTCCCCCTCGCCAATGA
AAAGTCTGCTGGTGCCCCTG

Product: Napthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MVGADTSSLMAVPAYPWIRQGNYDDVLFELSADEGIARISINRPEKRNAFRPRTVSELYDAFARVRDNPRIGVVLFTGAG
PAADGAYAFCAGGDQSVRGDGGYLDEEGTPRLNVLDLQRLIRSLPKVVIALVAGYAIGGGQVLHLLCDLSIAADNAQFGQ
TGPRVGSFDGGYGCAHLARLVGQRKAREIWFLCRRYNAEQALAMGLVNTVVPLAELESEGLCWAREVLQHSPTAIRCLKA
AFNADTDGMAGLQELAGQATHLFYRTEEGQEGRNAFLEKRAPDFSDQPWLP

Sequences:

>Translated_291_residues
MVGADTSSLMAVPAYPWIRQGNYDDVLFELSADEGIARISINRPEKRNAFRPRTVSELYDAFARVRDNPRIGVVLFTGAG
PAADGAYAFCAGGDQSVRGDGGYLDEEGTPRLNVLDLQRLIRSLPKVVIALVAGYAIGGGQVLHLLCDLSIAADNAQFGQ
TGPRVGSFDGGYGCAHLARLVGQRKAREIWFLCRRYNAEQALAMGLVNTVVPLAELESEGLCWAREVLQHSPTAIRCLKA
AFNADTDGMAGLQELAGQATHLFYRTEEGQEGRNAFLEKRAPDFSDQPWLP
>Mature_291_residues
MVGADTSSLMAVPAYPWIRQGNYDDVLFELSADEGIARISINRPEKRNAFRPRTVSELYDAFARVRDNPRIGVVLFTGAG
PAADGAYAFCAGGDQSVRGDGGYLDEEGTPRLNVLDLQRLIRSLPKVVIALVAGYAIGGGQVLHLLCDLSIAADNAQFGQ
TGPRVGSFDGGYGCAHLARLVGQRKAREIWFLCRRYNAEQALAMGLVNTVVPLAELESEGLCWAREVLQHSPTAIRCLKA
AFNADTDGMAGLQELAGQATHLFYRTEEGQEGRNAFLEKRAPDFSDQPWLP

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=280, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=30.46875, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4502327, Length=265, Percent_Identity=29.811320754717, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788597, Length=286, Percent_Identity=63.6363636363636, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=31.6602316602317, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=31.6793893129771, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082183, Length=258, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=30.2681992337165, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=31.1284046692607, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=27.6264591439689, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=223, Percent_Identity=30.0448430493274, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=210, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=270, Percent_Identity=29.2592592592593, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653477, Length=270, Percent_Identity=29.2592592592593, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653139, Length=285, Percent_Identity=30.8771929824561, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357171, Length=213, Percent_Identity=29.1079812206573, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922422, Length=270, Percent_Identity=23.7037037037037, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654903, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650670, Length=256, Percent_Identity=26.171875, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 31603; Mature: 31603

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGADTSSLMAVPAYPWIRQGNYDDVLFELSADEGIARISINRPEKRNAFRPRTVSELYD
CCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHCCCCCCCHHHHHHH
AFARVRDNPRIGVVLFTGAGPAADGAYAFCAGGDQSVRGDGGYLDEEGTPRLNVLDLQRL
HHHHHCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IRSLPKVVIALVAGYAIGGGQVLHLLCDLSIAADNAQFGQTGPRVGSFDGGYGCAHLARL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VGQRKAREIWFLCRRYNAEQALAMGLVNTVVPLAELESEGLCWAREVLQHSPTAIRCLKA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHH
AFNADTDGMAGLQELAGQATHLFYRTEEGQEGRNAFLEKRAPDFSDQPWLP
HHCCCCCHHHHHHHHCCHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVGADTSSLMAVPAYPWIRQGNYDDVLFELSADEGIARISINRPEKRNAFRPRTVSELYD
CCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHCCCCCCCHHHHHHH
AFARVRDNPRIGVVLFTGAGPAADGAYAFCAGGDQSVRGDGGYLDEEGTPRLNVLDLQRL
HHHHHCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IRSLPKVVIALVAGYAIGGGQVLHLLCDLSIAADNAQFGQTGPRVGSFDGGYGCAHLARL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VGQRKAREIWFLCRRYNAEQALAMGLVNTVVPLAELESEGLCWAREVLQHSPTAIRCLKA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHH
AFNADTDGMAGLQELAGQATHLFYRTEEGQEGRNAFLEKRAPDFSDQPWLP
HHCCCCCHHHHHHHHCCHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]