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The map label for this gene is frr [H]

Identifier: 148241959

GI number: 148241959

Start: 780762

End: 781301

Strand: Direct

Name: frr [H]

Synonym: SynRCC307_0860

Alternate gene names: 148241959

Gene position: 780762-781301 (Clockwise)

Preceding gene: 148241958

Following gene: 148241960

Centisome position: 35.09

GC content: 55.56

Gene sequence:

>540_bases
ATGGATCTTGAAGACAGCATGTCCAAGTCGCTGGAAGCCACCCAGCGCAACTTCAACACCATTCGCACCGGCCGGGCCAA
CACCTCCCTGCTCGACAAGGTGATGGTGGAGTACTACGGCGCCGATACGCCCCTGAAATCCCTGGCCACGATTTCAGCGC
CCGATTCCCAAACGATCCAGATCCAACCCTTTGACATGGGCTCGATGGCCTTGATCGAGAAGGCGATTGGCATGAGTGAT
CTGGGCCTGACCCCCAACAACGACGGCAAGTTGATTCGCATCAACATTCCTCCCCTCACCGAGGAACGCCGCAAGGAGCT
CTGCAAGATCGCCTCCAAATACGCCGAAGAGGGCAAGGTGGCCCTGCGCAATGTGCGCCGCGATGCGATCGATCAGATCA
AAAAACGTGAAAAAGATGGTGAGCTCTCGGAAGATCTCAGCCGTGATGAGCAGGACAAGGTTCAAAAGGTGACCGACAAG
TTCATCGCCGATTTGGAGAAACTGCTGGCTGATAAAGAAGCCGACATCCTCAAGGTGTGA

Upstream 100 bases:

>100_bases
CCATCCCCATCGTGGTGTTTGATCTGTTTGGTTCCGGCAACATTTCCCGGGCCGTTGCCGGTGAACCGATCGGGACCCGA
ATTACATCCGCTGCTTGACC

Downstream 100 bases:

>100_bases
GTTTCGATGTTGCTGTGGTGGGTGCTGGTGCCGCCGGGGCGGCATCGGCCTACCAACTCGCCCTGCGTGGACGCTCGGTT
GTCTTGATCGATGAGCGCGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MDLEDSMSKSLEATQRNFNTIRTGRANTSLLDKVMVEYYGADTPLKSLATISAPDSQTIQIQPFDMGSMALIEKAIGMSD
LGLTPNNDGKLIRINIPPLTEERRKELCKIASKYAEEGKVALRNVRRDAIDQIKKREKDGELSEDLSRDEQDKVQKVTDK
FIADLEKLLADKEADILKV

Sequences:

>Translated_179_residues
MDLEDSMSKSLEATQRNFNTIRTGRANTSLLDKVMVEYYGADTPLKSLATISAPDSQTIQIQPFDMGSMALIEKAIGMSD
LGLTPNNDGKLIRINIPPLTEERRKELCKIASKYAEEGKVALRNVRRDAIDQIKKREKDGELSEDLSRDEQDKVQKVTDK
FIADLEKLLADKEADILKV
>Mature_179_residues
MDLEDSMSKSLEATQRNFNTIRTGRANTSLLDKVMVEYYGADTPLKSLATISAPDSQTIQIQPFDMGSMALIEKAIGMSD
LGLTPNNDGKLIRINIPPLTEERRKELCKIASKYAEEGKVALRNVRRDAIDQIKKREKDGELSEDLSRDEQDKVQKVTDK
FIADLEKLLADKEADILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=32.0224719101124, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=33.5570469798658, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=52.5423728813559, Blast_Score=176, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20087; Mature: 20087

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEDSMSKSLEATQRNFNTIRTGRANTSLLDKVMVEYYGADTPLKSLATISAPDSQTIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEE
IQPFDMGSMALIEKAIGMSDLGLTPNNDGKLIRINIPPLTEERRKELCKIASKYAEEGKV
EECCCCCHHHHHHHHHCCHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ALRNVRRDAIDQIKKREKDGELSEDLSRDEQDKVQKVTDKFIADLEKLLADKEADILKV
HHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC
>Mature Secondary Structure
MDLEDSMSKSLEATQRNFNTIRTGRANTSLLDKVMVEYYGADTPLKSLATISAPDSQTIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEE
IQPFDMGSMALIEKAIGMSDLGLTPNNDGKLIRINIPPLTEERRKELCKIASKYAEEGKV
EECCCCCHHHHHHHHHCCHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ALRNVRRDAIDQIKKREKDGELSEDLSRDEQDKVQKVTDKFIADLEKLLADKEADILKV
HHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA