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The map label for this gene is pyrH

Identifier: 148241958

GI number: 148241958

Start: 780046

End: 780759

Strand: Direct

Name: pyrH

Synonym: SynRCC307_0859

Alternate gene names: 148241958

Gene position: 780046-780759 (Clockwise)

Preceding gene: 148241956

Following gene: 148241959

Centisome position: 35.06

GC content: 60.78

Gene sequence:

>714_bases
ATGGCTTACCAAAGGGTTCTGCTCAAACTCAGCGGCGAAGCCCTGATGGGTGACCAGGGTTACGGCATTGATCCCGCCAT
CGTTAGTGCGATTGCCAAAGACGTGGCCGAGGTGGTCGCCAAGGGCACCCAGCTCGCCATCGTTGTGGGAGGCGGCAACA
TCTTCCGCGGGCTGAAGGGATCAGCTGCCGGCATGGAGCGGGCCACGGCCGATTACGTCGGCATGTTGGCCACGGTGATG
AATGCGATCACCTTGCAAGACGGCTTGGAGCGGGCCGGTGTTCCCACCCGGGTGCAAAGCGCTATCGCCATGCAGGAGGT
GGCGGAGCCTTACATCCGCCGCAAGGCGATGCGGCATCTCGAGAAGGGGCGAGTGGTGATCTTCGGTGCCGGCTGCGGCA
ATCCCTTTTTCACCACCGACACCACCGCGGCTTTGCGCGCTGCTGAGATCAACGCCCATGTGGTGCTCAAGGCGACCAAG
GTGGACGGTGTCTATGACAAAGATCCGGTGCGCTTCCCTGATGCGGTGCGCTATGAGCACCTCACCTTCCAAGACGTCTT
GGCCAATGAGCTAGGCGTCATGGATGCCACCGCCATTGCCCTGTGCAAAGACAACACCATCCCCATCGTGGTGTTTGATC
TGTTTGGTTCCGGCAACATTTCCCGGGCCGTTGCCGGTGAACCGATCGGGACCCGAATTACATCCGCTGCTTGA

Upstream 100 bases:

>100_bases
GGTGATCCCAGTTGGACCATGCAAGCGAGCGGCACTGACTGTTGCAACCCCCGGCCTGGGCTGAAGGCGCTTGCTACTGT
TCGCCGGACAGACTTCAGCG

Downstream 100 bases:

>100_bases
CCATGGATCTTGAAGACAGCATGTCCAAGTCGCTGGAAGCCACCCAGCGCAACTTCAACACCATTCGCACCGGCCGGGCC
AACACCTCCCTGCTCGACAA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MAYQRVLLKLSGEALMGDQGYGIDPAIVSAIAKDVAEVVAKGTQLAIVVGGGNIFRGLKGSAAGMERATADYVGMLATVM
NAITLQDGLERAGVPTRVQSAIAMQEVAEPYIRRKAMRHLEKGRVVIFGAGCGNPFFTTDTTAALRAAEINAHVVLKATK
VDGVYDKDPVRFPDAVRYEHLTFQDVLANELGVMDATAIALCKDNTIPIVVFDLFGSGNISRAVAGEPIGTRITSAA

Sequences:

>Translated_237_residues
MAYQRVLLKLSGEALMGDQGYGIDPAIVSAIAKDVAEVVAKGTQLAIVVGGGNIFRGLKGSAAGMERATADYVGMLATVM
NAITLQDGLERAGVPTRVQSAIAMQEVAEPYIRRKAMRHLEKGRVVIFGAGCGNPFFTTDTTAALRAAEINAHVVLKATK
VDGVYDKDPVRFPDAVRYEHLTFQDVLANELGVMDATAIALCKDNTIPIVVFDLFGSGNISRAVAGEPIGTRITSAA
>Mature_236_residues
AYQRVLLKLSGEALMGDQGYGIDPAIVSAIAKDVAEVVAKGTQLAIVVGGGNIFRGLKGSAAGMERATADYVGMLATVMN
AITLQDGLERAGVPTRVQSAIAMQEVAEPYIRRKAMRHLEKGRVVIFGAGCGNPFFTTDTTAALRAAEINAHVVLKATKV
DGVYDKDPVRFPDAVRYEHLTFQDVLANELGVMDATAIALCKDNTIPIVVFDLFGSGNISRAVAGEPIGTRITSAA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=50.6437768240343, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRH_SYNR3 (A5GSA3)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227115.1
- ProteinModelPortal:   A5GSA3
- SMR:   A5GSA3
- STRING:   A5GSA3
- GeneID:   5156688
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_0859
- eggNOG:   COG0528
- HOGENOM:   HBG497552
- OMA:   RHMEKGR
- ProtClustDB:   PRK00358
- GO:   GO:0005737
- HAMAP:   MF_01220_B
- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF005650
- TIGRFAMs:   TIGR02075

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.4.22

Molecular weight: Translated: 25010; Mature: 24879

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: BINDING 51-51 BINDING 52-52 BINDING 56-56 BINDING 71-71 BINDING 159-159 BINDING 165-165 BINDING 168-168

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQRVLLKLSGEALMGDQGYGIDPAIVSAIAKDVAEVVAKGTQLAIVVGGGNIFRGLKG
CCHHHEEHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCCCC
SAAGMERATADYVGMLATVMNAITLQDGLERAGVPTRVQSAIAMQEVAEPYIRRKAMRHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVIFGAGCGNPFFTTDTTAALRAAEINAHVVLKATKVDGVYDKDPVRFPDAVRYEH
HCCCEEEEECCCCCCCCCCCHHHHHHHEECCEEEEEEEEEECCCCCCCCCCCCCCHHHHH
LTFQDVLANELGVMDATAIALCKDNTIPIVVFDLFGSGNISRAVAGEPIGTRITSAA
CHHHHHHHHHCCCHHHHEEEEECCCCCEEEEEEECCCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AYQRVLLKLSGEALMGDQGYGIDPAIVSAIAKDVAEVVAKGTQLAIVVGGGNIFRGLKG
CHHHEEHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCCCC
SAAGMERATADYVGMLATVMNAITLQDGLERAGVPTRVQSAIAMQEVAEPYIRRKAMRHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVIFGAGCGNPFFTTDTTAALRAAEINAHVVLKATKVDGVYDKDPVRFPDAVRYEH
HCCCEEEEECCCCCCCCCCCHHHHHHHEECCEEEEEEEEEECCCCCCCCCCCCCCHHHHH
LTFQDVLANELGVMDATAIALCKDNTIPIVVFDLFGSGNISRAVAGEPIGTRITSAA
CHHHHHHHHHCCCHHHHEEEEECCCCCEEEEEEECCCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA