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The map label for this gene is gmk [H]

Identifier: 148241807

GI number: 148241807

Start: 640554

End: 641120

Strand: Direct

Name: gmk [H]

Synonym: SynRCC307_0708

Alternate gene names: 148241807

Gene position: 640554-641120 (Clockwise)

Preceding gene: 148241804

Following gene: 148241810

Centisome position: 28.79

GC content: 62.96

Gene sequence:

>567_bases
GTGAGCCCAGCCCCGCATCAACCTCGCCTCACCGTTTTGAGTGGTCCCAGTGGCGTGGGCAAAGGCACCTTGGTGGGCCT
GTTGCGTCAACGCCACCCGGAGCTGTGGTTATCGGTCTCCGCCACCACCCGTGCGCCGCGCCCTGGTGAGGAGAACGGCA
TTCACTACTTCTTCCACAGCCAAGACAGCTTTCAGCAGCTCGTGGATCAAAGCGGGCTGCTGGAGTGGGCGAGCTTTGCT
GGCAATTGCTACGGAACCCCCCGTCAGCCTGTGGAGGAGCGCTTGGCTGCCGGCGTGCCCGTGCTGCTTGAGATTGAGCT
GGAGGGAGCCCGTCAGGTGCGCCAGAGCAGCCCTGATGCGTTTCAAATCTTTTTGCGCCCCCCATCGTTTGAGGAGTTGG
AGCGCCGCATTCGTGGCCGTGGCACCGACAGTGACGAGGCCATCCAACGCCGCCTCGAGCGGGCGCGCCTGGAACTGCAA
GCCGAATCAGAATTTGATGCTGTGGTGGAAAACGGTGAGCTCGATGTAGCCCTGCAGGAGCTGGAGCGCTTGATGGGCCT
GGCGTAG

Upstream 100 bases:

>100_bases
GAGTTCGTGGACCACGCCCCGCAGTGTTGTGGTGTCCTGCGGTTGCATGGCGCCTCCCTTCACGCCCTAGTTTCCACTCA
GGCCCCATCTCTGCCGCTTC

Downstream 100 bases:

>100_bases
CTCGCTGGGTTCAAGGCACAAAAAAAAGGCCCCTCAAAGGGACCTTCCTTGATTGGCTTGAAATCCTCGCTTCATAACGG
GTGGAAGAGGAGATCAGGGA

Product: guanylate kinase

Products: NA

Alternate protein names: GMP kinase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSPAPHQPRLTVLSGPSGVGKGTLVGLLRQRHPELWLSVSATTRAPRPGEENGIHYFFHSQDSFQQLVDQSGLLEWASFA
GNCYGTPRQPVEERLAAGVPVLLEIELEGARQVRQSSPDAFQIFLRPPSFEELERRIRGRGTDSDEAIQRRLERARLELQ
AESEFDAVVENGELDVALQELERLMGLA

Sequences:

>Translated_188_residues
MSPAPHQPRLTVLSGPSGVGKGTLVGLLRQRHPELWLSVSATTRAPRPGEENGIHYFFHSQDSFQQLVDQSGLLEWASFA
GNCYGTPRQPVEERLAAGVPVLLEIELEGARQVRQSSPDAFQIFLRPPSFEELERRIRGRGTDSDEAIQRRLERARLELQ
AESEFDAVVENGELDVALQELERLMGLA
>Mature_187_residues
SPAPHQPRLTVLSGPSGVGKGTLVGLLRQRHPELWLSVSATTRAPRPGEENGIHYFFHSQDSFQQLVDQSGLLEWASFAG
NCYGTPRQPVEERLAAGVPVLLEIELEGARQVRQSSPDAFQIFLRPPSFEELERRIRGRGTDSDEAIQRRLERARLELQA
ESEFDAVVENGELDVALQELERLMGLA

Specific function: Essential for recycling GMP and indirectly, cGMP [H]

COG id: COG0194

COG function: function code F; Guanylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate kinase-like domain [H]

Homologues:

Organism=Homo sapiens, GI226874831, Length=179, Percent_Identity=39.6648044692737, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI226874833, Length=179, Percent_Identity=39.6648044692737, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI4504221, Length=179, Percent_Identity=39.6648044692737, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI21389483, Length=181, Percent_Identity=29.8342541436464, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI186972120, Length=182, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI186700629, Length=182, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI186700627, Length=182, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI38570142, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI14780902, Length=184, Percent_Identity=27.7173913043478, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4505237, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI262118263, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI262118259, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI262118255, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI21361598, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI111154074, Length=159, Percent_Identity=29.559748427673, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1790080, Length=181, Percent_Identity=44.1988950276243, Blast_Score=164, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI193203132, Length=182, Percent_Identity=40.6593406593407, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17508835, Length=182, Percent_Identity=40.6593406593407, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71988041, Length=187, Percent_Identity=24.5989304812834, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71988048, Length=179, Percent_Identity=25.1396648044693, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17557440, Length=187, Percent_Identity=25.668449197861, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320662, Length=182, Percent_Identity=40.6593406593407, Blast_Score=137, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21356141, Length=182, Percent_Identity=38.4615384615385, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI221330162, Length=194, Percent_Identity=28.8659793814433, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330166, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330164, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008144
- InterPro:   IPR008145
- InterPro:   IPR020590
- InterPro:   IPR017665 [H]

Pfam domain/function: PF00625 Guanylate_kin [H]

EC number: =2.7.4.8 [H]

Molecular weight: Translated: 20968; Mature: 20837

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00856 GUANYLATE_KINASE_1 ; PS50052 GUANYLATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAPHQPRLTVLSGPSGVGKGTLVGLLRQRHPELWLSVSATTRAPRPGEENGIHYFFHS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
QDSFQQLVDQSGLLEWASFAGNCYGTPRQPVEERLAAGVPVLLEIELEGARQVRQSSPDA
CHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHCCCCE
FQIFLRPPSFEELERRIRGRGTDSDEAIQRRLERARLELQAESEFDAVVENGELDVALQE
EEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHH
LERLMGLA
HHHHHCCC
>Mature Secondary Structure 
SPAPHQPRLTVLSGPSGVGKGTLVGLLRQRHPELWLSVSATTRAPRPGEENGIHYFFHS
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
QDSFQQLVDQSGLLEWASFAGNCYGTPRQPVEERLAAGVPVLLEIELEGARQVRQSSPDA
CHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHCCCCE
FQIFLRPPSFEELERRIRGRGTDSDEAIQRRLERARLELQAESEFDAVVENGELDVALQE
EEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHH
LERLMGLA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA