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The map label for this gene is trxA [H]

Identifier: 148241752

GI number: 148241752

Start: 592803

End: 593135

Strand: Direct

Name: trxA [H]

Synonym: SynRCC307_0653

Alternate gene names: 148241752

Gene position: 592803-593135 (Clockwise)

Preceding gene: 148241751

Following gene: 148241753

Centisome position: 26.64

GC content: 63.36

Gene sequence:

>333_bases
GTGCCGCCTCCAGTGACTGTCCACAGCCTCAGTGATGCCAACTTCCAGGCCGAGGTGATGGAGTATTCCGGACTGGTATT
GGTGGATGTGTGGGCCACCTGGTGCGGCCCCTGCCGCCTGATGGCGCCGTTGATGGATTGGGCCGCCAGCACCTATGGCG
ATGGCCTCAAGGTGGGCAAGTTGGAGGCTGACCCCAATCCCACCAGCCGCGATGCTCTGCAAGTGCAGGGGTTGCCGGCC
TTGGTGCTGTTCCGCAATGGCCAGGAATTGGCGCGCCATGAGGGCGCCATGGCGCAGCCCCAGTTGAAGGCCTTCTTGGA
TGCCCATCTCTGA

Upstream 100 bases:

>100_bases
CTGCCCAGCAGGCCCAGGTCGATGAGGAGCTCGAGTCGCTGAAGCGCTCGATCGATCAGCTCTAACGCCCGGCCAGCTGC
CTAGGATCAGTCCTGTTTGA

Downstream 100 bases:

>100_bases
GCGTCTCGGGCAACTGGGCTCCGGCGTTTTTGGCCGGGTTGACGGTGAAAAACGCAGTTACCGCCTCTCGCAGCAACAGC
CGCAGCGTCCGCTGATTGAT

Product: thioredoxin

Products: NA

Alternate protein names: Trx-2 [H]

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MPPPVTVHSLSDANFQAEVMEYSGLVLVDVWATWCGPCRLMAPLMDWAASTYGDGLKVGKLEADPNPTSRDALQVQGLPA
LVLFRNGQELARHEGAMAQPQLKAFLDAHL

Sequences:

>Translated_110_residues
MPPPVTVHSLSDANFQAEVMEYSGLVLVDVWATWCGPCRLMAPLMDWAASTYGDGLKVGKLEADPNPTSRDALQVQGLPA
LVLFRNGQELARHEGAMAQPQLKAFLDAHL
>Mature_109_residues
PPPVTVHSLSDANFQAEVMEYSGLVLVDVWATWCGPCRLMAPLMDWAASTYGDGLKVGKLEADPNPTSRDALQVQGLPAL
VLFRNGQELARHEGAMAQPQLKAFLDAHL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=43.2692307692308, Blast_Score=102, Evalue=8e-24,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11945; Mature: 11814

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPPVTVHSLSDANFQAEVMEYSGLVLVDVWATWCGPCRLMAPLMDWAASTYGDGLKVGK
CCCCCEEECCCCCCCCEEEHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCEEEEE
LEADPNPTSRDALQVQGLPALVLFRNGQELARHEGAMAQPQLKAFLDAHL
EECCCCCCCCCEEEECCCCEEEEEECCHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PPPVTVHSLSDANFQAEVMEYSGLVLVDVWATWCGPCRLMAPLMDWAASTYGDGLKVGK
CCCCEEECCCCCCCCEEEHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCEEEEE
LEADPNPTSRDALQVQGLPALVLFRNGQELARHEGAMAQPQLKAFLDAHL
EECCCCCCCCCEEEECCCCEEEEEECCHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492494; 11759840; 8590004 [H]