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The map label for this gene is dapL [H]

Identifier: 148241753

GI number: 148241753

Start: 593122

End: 594312

Strand: Direct

Name: dapL [H]

Synonym: SynRCC307_0654

Alternate gene names: 148241753

Gene position: 593122-594312 (Clockwise)

Preceding gene: 148241752

Following gene: 148241754

Centisome position: 26.66

GC content: 65.07

Gene sequence:

>1191_bases
ATGCCCATCTCTGAGCGTCTCGGGCAACTGGGCTCCGGCGTTTTTGGCCGGGTTGACGGTGAAAAACGCAGTTACCGCCT
CTCGCAGCAACAGCCGCAGCGTCCGCTGATTGATCTGTCGCTGGGGAGCTCTGATCTCAAGCCTCCCGTTCGGCTCTTGC
AGGTGATGGCCGAAGCGATCGCTGAGCCCCCCAGCAGCCGCTATTGCTTGCAGGCTGCCACCGCTCCGTTTCGCCAGGCC
GCGGCCGCCTGGCTCGAGGGGCGCTTCGGTGTGGCCGTGGATCCGGAGAAGGAAATTCTGCTGTTGGTGGGTTCCCAGGA
GGGCACCGCCCATCTGCCGTTGGCGGTGCTCAATCCCGGCGATCCGGCCTTGGTGCTGGATCCCAGCTACCCCAGCCATG
CCGGTGGGGTGGCCCTGGCTTCCGGTGAGTTGGTGCGTTTGCCGCTGTTGGCTGATCAGGGCTGGCGTCCAGCCTTTGAG
CAGCTCAGCGATGAGCAGCGGCGGCAGTTGCGTTTGTTGGTGCTGGGCTATCCCCATAACCCCACGGCCACCACGGGTTC
GCAGGAGTGGCTCGAGCAGGCCATGGCCATCGCCAAACGCAGTGATGCGGTGCTGGCCCACGACAACCCCTATGTCGATT
TGGCTCTGGAAGGGGAGGCTCCAGCGTTGCTGCGCTGTGATGGCTGGCGTGAGCGGGGCATTGAGTTTTTCTCCTTCTCC
AAAGGCTGGGGCCTGGCTGGATTTCGCCTGGCGTTTGCTGTGGGCGCTCCGGCCTTGATCGAGGCCTTGGCCCGGGTCAA
AGGGGTGGTGGATTTCAACCAGTCGCTGGCCTTGCAGGCTGGAGCCATTGCGGCACTGCAGGAGTTCCCGGATTGGCCGC
GGCAATTGTGCGATCGCTACCGCCAGCGCCGCGACCACATGGCCGAATTGCTCACGGCCGCTGGTTGGACGGTGCCCAAC
AGCTCGATGGCGCTTTACCAGTGGCTTCCCATCCCAGAACCCCTGCATGATCTCGGCAGTGAAGCGGCGGCCCAGTGGCT
GCTGCGCAGCAGTGGTGTGGCGCTCACGCCAGGGGTGGGCTTTGGCCCCAGCGGGGAAGGCTGGCTGCGGCTGGCGCTGG
TCGCCGATGAACCGGTGTTGGAGCAGGCCAGTGCACGCCTGCGGTTGGCCCTGGAGCAACGCACAATCTGA

Upstream 100 bases:

>100_bases
CAAGTGCAGGGGTTGCCGGCCTTGGTGCTGTTCCGCAATGGCCAGGAATTGGCGCGCCATGAGGGCGCCATGGCGCAGCC
CCAGTTGAAGGCCTTCTTGG

Downstream 100 bases:

>100_bases
AAATTTTCCCACGATGAGAAAACTTTGATACCCGTGCGACGCATGGTGGAAGCACTTGCATCCCCGCCATGAATCTCTGG
AGCCCTTGGTTAGATCCTGC

Product: aspartate/tyrosine/aromatic aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPISERLGQLGSGVFGRVDGEKRSYRLSQQQPQRPLIDLSLGSSDLKPPVRLLQVMAEAIAEPPSSRYCLQAATAPFRQA
AAAWLEGRFGVAVDPEKEILLLVGSQEGTAHLPLAVLNPGDPALVLDPSYPSHAGGVALASGELVRLPLLADQGWRPAFE
QLSDEQRRQLRLLVLGYPHNPTATTGSQEWLEQAMAIAKRSDAVLAHDNPYVDLALEGEAPALLRCDGWRERGIEFFSFS
KGWGLAGFRLAFAVGAPALIEALARVKGVVDFNQSLALQAGAIAALQEFPDWPRQLCDRYRQRRDHMAELLTAAGWTVPN
SSMALYQWLPIPEPLHDLGSEAAAQWLLRSSGVALTPGVGFGPSGEGWLRLALVADEPVLEQASARLRLALEQRTI

Sequences:

>Translated_396_residues
MPISERLGQLGSGVFGRVDGEKRSYRLSQQQPQRPLIDLSLGSSDLKPPVRLLQVMAEAIAEPPSSRYCLQAATAPFRQA
AAAWLEGRFGVAVDPEKEILLLVGSQEGTAHLPLAVLNPGDPALVLDPSYPSHAGGVALASGELVRLPLLADQGWRPAFE
QLSDEQRRQLRLLVLGYPHNPTATTGSQEWLEQAMAIAKRSDAVLAHDNPYVDLALEGEAPALLRCDGWRERGIEFFSFS
KGWGLAGFRLAFAVGAPALIEALARVKGVVDFNQSLALQAGAIAALQEFPDWPRQLCDRYRQRRDHMAELLTAAGWTVPN
SSMALYQWLPIPEPLHDLGSEAAAQWLLRSSGVALTPGVGFGPSGEGWLRLALVADEPVLEQASARLRLALEQRTI
>Mature_395_residues
PISERLGQLGSGVFGRVDGEKRSYRLSQQQPQRPLIDLSLGSSDLKPPVRLLQVMAEAIAEPPSSRYCLQAATAPFRQAA
AAWLEGRFGVAVDPEKEILLLVGSQEGTAHLPLAVLNPGDPALVLDPSYPSHAGGVALASGELVRLPLLADQGWRPAFEQ
LSDEQRRQLRLLVLGYPHNPTATTGSQEWLEQAMAIAKRSDAVLAHDNPYVDLALEGEAPALLRCDGWRERGIEFFSFSK
GWGLAGFRLAFAVGAPALIEALARVKGVVDFNQSLALQAGAIAALQEFPDWPRQLCDRYRQRRDHMAELLTAAGWTVPNS
SMALYQWLPIPEPLHDLGSEAAAQWLLRSSGVALTPGVGFGPSGEGWLRLALVADEPVLEQASARLRLALEQRTI

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=20.1550387596899, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=20.1550387596899, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI95147551, Length=390, Percent_Identity=20.2564102564103, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI169881279, Length=390, Percent_Identity=20.2564102564103, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788722, Length=349, Percent_Identity=35.243553008596, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=28.0612244897959, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=333, Percent_Identity=24.3243243243243, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=333, Percent_Identity=24.3243243243243, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=345, Percent_Identity=21.7391304347826, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=22.2506393861893, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=22.2506393861893, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=22.2506393861893, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=22.2506393861893, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 42989; Mature: 42857

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISERLGQLGSGVFGRVDGEKRSYRLSQQQPQRPLIDLSLGSSDLKPPVRLLQVMAEAI
CCHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
AEPPSSRYCLQAATAPFRQAAAAWLEGRFGVAVDPEKEILLLVGSQEGTAHLPLAVLNPG
CCCCCCCEEHHHHCCHHHHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCC
DPALVLDPSYPSHAGGVALASGELVRLPLLADQGWRPAFEQLSDEQRRQLRLLVLGYPHN
CCEEEECCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEECCCC
PTATTGSQEWLEQAMAIAKRSDAVLAHDNPYVDLALEGEAPALLRCDGWRERGIEFFSFS
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEEEECCCHHCCCEEEEEC
KGWGLAGFRLAFAVGAPALIEALARVKGVVDFNQSLALQAGAIAALQEFPDWPRQLCDRY
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RQRRDHMAELLTAAGWTVPNSSMALYQWLPIPEPLHDLGSEAAAQWLLRSSGVALTPGVG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCC
FGPSGEGWLRLALVADEPVLEQASARLRLALEQRTI
CCCCCCCEEEEEEEECCHHHHHHHHHHEEHHHHCCC
>Mature Secondary Structure 
PISERLGQLGSGVFGRVDGEKRSYRLSQQQPQRPLIDLSLGSSDLKPPVRLLQVMAEAI
CHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
AEPPSSRYCLQAATAPFRQAAAAWLEGRFGVAVDPEKEILLLVGSQEGTAHLPLAVLNPG
CCCCCCCEEHHHHCCHHHHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCC
DPALVLDPSYPSHAGGVALASGELVRLPLLADQGWRPAFEQLSDEQRRQLRLLVLGYPHN
CCEEEECCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEECCCC
PTATTGSQEWLEQAMAIAKRSDAVLAHDNPYVDLALEGEAPALLRCDGWRERGIEFFSFS
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEEEECCCHHCCCEEEEEC
KGWGLAGFRLAFAVGAPALIEALARVKGVVDFNQSLALQAGAIAALQEFPDWPRQLCDRY
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RQRRDHMAELLTAAGWTVPNSSMALYQWLPIPEPLHDLGSEAAAQWLLRSSGVALTPGVG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCC
FGPSGEGWLRLALVADEPVLEQASARLRLALEQRTI
CCCCCCCEEEEEEEECCHHHHHHHHHHEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA