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The map label for this gene is manC [H]

Identifier: 148241748

GI number: 148241748

Start: 588202

End: 589653

Strand: Direct

Name: manC [H]

Synonym: SynRCC307_0649

Alternate gene names: 148241748

Gene position: 588202-589653 (Clockwise)

Preceding gene: 148241747

Following gene: 148241749

Centisome position: 26.44

GC content: 64.26

Gene sequence:

>1452_bases
ATGCCCAAGACCTCTGCATTGCTGCCGGTGATCCTTTGTGGTGGCACGGGCACCCGCCTGTGGCCCCTATCGCGGGCGAG
TTACCCCAAGCAGTATTGGGCCCTGGCCCATAACGCCGAAGACACGCTGCTGCAGCTCACCCAACGGCGCCTCGAAGGCT
TGCCGGGTCTGGGCTCACCGATCTTGATCTGCAACGAAGACCACCGCTTCATCGTGGCCGAGCAGATGCGCCAGCTCGGG
GTGGAGCCGGAGTCGATCTTGCTGGAGCCCATGGGCCGCAACACCGCTCCGGCGGTGTGTGTGGCGGCGTTGCGGGCTAC
CGCTCGCGGTGAAGACCCCTTGCTGCTGGTGCTGGCGGCTGATCACGTCATCCGTGAGCCCGAGAAGTTCCGCGCCACGG
TGGAAGCCGGGATTCCGGCGGCGGAAGCGGGCCGGCTGGTGACCTTTGGCATCGTGCCCACGGCCCCGGAAACGGGCTAC
GGCTACATCGAATCGGCTGAGGCCCTCAATGCCTCCTCGCCGGTGCCGATTGCCCGCTTTGTGGAGAAGCCTGATCGCGC
CACCGCCGAGCAGTTTTTGGCCAGTGGCCGTTTCACTTGGAACAGCGGCATGTTCCTGTTCCGCGCCAGCGCCATGCTCG
CCGAACTCGAGCGCCTGGCCCCTGAATTGGTGAGCTGCTGCCGCTCGGCCCTGGAGCACGACACCCCCGACTTGCAGTTC
TTGCGGCTTGATCGTGAGGCCTTTGCCCAATGCCCTTCGGTGGCTCTCGATGTGGCTGTGATGGAGCGCACGCCGCTGGG
TTCGGTGTTGCCGCTTGATGCCGGTTGGAGTGATGTGGGCAGCTGGAGTGCCCTATGGGAAACCGCTGATCAAGACGAGA
ACGGCAACGTCTTGCGCGGTCGCGTGATCTCGGAAGGCAGCCGCAACTGTTATCTGCGCAGTGAGCACCGCCTGGTGGTG
GGCCTGGGCGTTGAAAACCTGGTGGTGGTGGAAACCGATGACGCCGTGTTGATCGCTGAGCGCAGCCAGGCGCAAAACGT
CAAAGCGATCGTTCAGCAGCTCGAAGCCGACGGCAGCTCAGAAGGCAAAGCCCACCGGCGCATCTACCGGCCTTGGGGCC
ACTACACCTCCATCGTTGAGGGCAGCCGCTGGCAGGTGAAGCGCATTTCGGTGAAGCCTGGCGCCAGCCTGTCGCTGCAG
ATGCACCACCACCGCGCCGAGCATTGGGTGGTGGTGCGCGGCACGGCCCTGGTGGAGAAGAATGGAGTGGAGGAGCTGAT
TGGTGAAAACCAGAGCACCTACATCCCCTTAGGGGCGCAGCATCGCCTCAGCAACCCGGGCAAGATCCCGGTGGAGATGA
TCGAGATCCAAAGCGGCGCCTACCTTGGTGAAGACGACATCGTCCGCCTCGAAGATGTCTACGGCCGCTCGACGGCCGTA
AGCCGTGCCTGA

Upstream 100 bases:

>100_bases
TTGCAGCAGCGTGGCCAGGCCTTAGCGGCCTCCGGTGTGGAATCCACCTGGCGCCTGCCCAACCTCGAGCGATACTGAGC
GCCCCCGTTCGGCTAGGTCC

Downstream 100 bases:

>100_bases
AGCCGCTGGATTTCTTGCTGCTGCCAGCACGCCGCACGGGTTAATCACCCTGCTGGTGTTTGCCGTTTCGCTGGTTCTGT
TCATCAGCGGTTGGTTGGCG

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MPKTSALLPVILCGGTGTRLWPLSRASYPKQYWALAHNAEDTLLQLTQRRLEGLPGLGSPILICNEDHRFIVAEQMRQLG
VEPESILLEPMGRNTAPAVCVAALRATARGEDPLLLVLAADHVIREPEKFRATVEAGIPAAEAGRLVTFGIVPTAPETGY
GYIESAEALNASSPVPIARFVEKPDRATAEQFLASGRFTWNSGMFLFRASAMLAELERLAPELVSCCRSALEHDTPDLQF
LRLDREAFAQCPSVALDVAVMERTPLGSVLPLDAGWSDVGSWSALWETADQDENGNVLRGRVISEGSRNCYLRSEHRLVV
GLGVENLVVVETDDAVLIAERSQAQNVKAIVQQLEADGSSEGKAHRRIYRPWGHYTSIVEGSRWQVKRISVKPGASLSLQ
MHHHRAEHWVVVRGTALVEKNGVEELIGENQSTYIPLGAQHRLSNPGKIPVEMIEIQSGAYLGEDDIVRLEDVYGRSTAV
SRA

Sequences:

>Translated_483_residues
MPKTSALLPVILCGGTGTRLWPLSRASYPKQYWALAHNAEDTLLQLTQRRLEGLPGLGSPILICNEDHRFIVAEQMRQLG
VEPESILLEPMGRNTAPAVCVAALRATARGEDPLLLVLAADHVIREPEKFRATVEAGIPAAEAGRLVTFGIVPTAPETGY
GYIESAEALNASSPVPIARFVEKPDRATAEQFLASGRFTWNSGMFLFRASAMLAELERLAPELVSCCRSALEHDTPDLQF
LRLDREAFAQCPSVALDVAVMERTPLGSVLPLDAGWSDVGSWSALWETADQDENGNVLRGRVISEGSRNCYLRSEHRLVV
GLGVENLVVVETDDAVLIAERSQAQNVKAIVQQLEADGSSEGKAHRRIYRPWGHYTSIVEGSRWQVKRISVKPGASLSLQ
MHHHRAEHWVVVRGTALVEKNGVEELIGENQSTYIPLGAQHRLSNPGKIPVEMIEIQSGAYLGEDDIVRLEDVYGRSTAV
SRA
>Mature_482_residues
PKTSALLPVILCGGTGTRLWPLSRASYPKQYWALAHNAEDTLLQLTQRRLEGLPGLGSPILICNEDHRFIVAEQMRQLGV
EPESILLEPMGRNTAPAVCVAALRATARGEDPLLLVLAADHVIREPEKFRATVEAGIPAAEAGRLVTFGIVPTAPETGYG
YIESAEALNASSPVPIARFVEKPDRATAEQFLASGRFTWNSGMFLFRASAMLAELERLAPELVSCCRSALEHDTPDLQFL
RLDREAFAQCPSVALDVAVMERTPLGSVLPLDAGWSDVGSWSALWETADQDENGNVLRGRVISEGSRNCYLRSEHRLVVG
LGVENLVVVETDDAVLIAERSQAQNVKAIVQQLEADGSSEGKAHRRIYRPWGHYTSIVEGSRWQVKRISVKPGASLSLQM
HHHRAEHWVVVRGTALVEKNGVEELIGENQSTYIPLGAQHRLSNPGKIPVEMIEIQSGAYLGEDDIVRLEDVYGRSTAVS
RA

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=477, Percent_Identity=55.9748427672956, Blast_Score=526, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 52896; Mature: 52765

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTSALLPVILCGGTGTRLWPLSRASYPKQYWALAHNAEDTLLQLTQRRLEGLPGLGSP
CCCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
ILICNEDHRFIVAEQMRQLGVEPESILLEPMGRNTAPAVCVAALRATARGEDPLLLVLAA
EEEECCCCCEEHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
DHVIREPEKFRATVEAGIPAAEAGRLVTFGIVPTAPETGYGYIESAEALNASSPVPIARF
CHHHCCCHHHHHHHHCCCCCHHCCCEEEEEEECCCCCCCCCCEECHHHCCCCCCCCHHHH
VEKPDRATAEQFLASGRFTWNSGMFLFRASAMLAELERLAPELVSCCRSALEHDTPDLQF
HCCCCHHHHHHHHHCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LRLDREAFAQCPSVALDVAVMERTPLGSVLPLDAGWSDVGSWSALWETADQDENGNVLRG
EEECHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEE
RVISEGSRNCYLRSEHRLVVGLGVENLVVVETDDAVLIAERSQAQNVKAIVQQLEADGSS
EEECCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCC
EGKAHRRIYRPWGHYTSIVEGSRWQVKRISVKPGASLSLQMHHHRAEHWVVVRGTALVEK
CCCHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEEEEEEEECC
NGVEELIGENQSTYIPLGAQHRLSNPGKIPVEMIEIQSGAYLGEDDIVRLEDVYGRSTAV
CCHHHHHCCCCCEEEECCCHHCCCCCCCCCEEEEEEECCCEECCCCCEEEHHHCCCCHHC
SRA
CCC
>Mature Secondary Structure 
PKTSALLPVILCGGTGTRLWPLSRASYPKQYWALAHNAEDTLLQLTQRRLEGLPGLGSP
CCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
ILICNEDHRFIVAEQMRQLGVEPESILLEPMGRNTAPAVCVAALRATARGEDPLLLVLAA
EEEECCCCCEEHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
DHVIREPEKFRATVEAGIPAAEAGRLVTFGIVPTAPETGYGYIESAEALNASSPVPIARF
CHHHCCCHHHHHHHHCCCCCHHCCCEEEEEEECCCCCCCCCCEECHHHCCCCCCCCHHHH
VEKPDRATAEQFLASGRFTWNSGMFLFRASAMLAELERLAPELVSCCRSALEHDTPDLQF
HCCCCHHHHHHHHHCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LRLDREAFAQCPSVALDVAVMERTPLGSVLPLDAGWSDVGSWSALWETADQDENGNVLRG
EEECHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEE
RVISEGSRNCYLRSEHRLVVGLGVENLVVVETDDAVLIAERSQAQNVKAIVQQLEADGSS
EEECCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCC
EGKAHRRIYRPWGHYTSIVEGSRWQVKRISVKPGASLSLQMHHHRAEHWVVVRGTALVEK
CCCHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEEEEEEEECC
NGVEELIGENQSTYIPLGAQHRLSNPGKIPVEMIEIQSGAYLGEDDIVRLEDVYGRSTAV
CCHHHHHCCCCCEEEECCCHHCCCCCCCCCEEEEEEECCCEECCCCCEEEHHHCCCCHHC
SRA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]