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The map label for this gene is engA

Identifier: 148241565

GI number: 148241565

Start: 435710

End: 437068

Strand: Direct

Name: engA

Synonym: SynRCC307_0466

Alternate gene names: 148241565

Gene position: 435710-437068 (Clockwise)

Preceding gene: 148241563

Following gene: 148241566

Centisome position: 19.58

GC content: 63.21

Gene sequence:

>1359_bases
GTGGCCCTGCCGGTGGTGGCCATCATCGGACGGCCCAACGTGGGCAAGTCCACTTTGGTGAATCGTCTGTGCCGAAGTCG
CGACGCGATCGTCCATGACGAGCCGGGTGTAACCCGCGATCGCACCTACCAAGAGGGTTTCTGGGGTGGCCGCACCTTTC
GGGTGGTGGACACCGGTGGCTTGGTCTTCGACGACGACAGTGAGTTTCTGCCGGAGATCCGCGAGCAGGCCAGCTTGGCG
ATGGCCGAAGCCTGCGTGGCCCTCGTGATCGTTGATGGCCAGCAAGGGCTCACGGCCGCCGATGAAGCCATTGCCGCTTG
GTTGCGCCAGCAGAAGTGTCCGGTGTTGTTGGGCGTCAATAAATGCGAGTCCCCTGAGCAGGGCTTGGCCATGGCGGCTG
AGTTCTGGGCGCTCGGCTTGGGCGAGCCCAAGCCCATCTCCGCGATCCATGGCGCCGGCACCGGGGACTTGCTCGATCAG
GTGCTCGACTTTTTGCCTCCGCAAGATGAAGAGGAGGCCCCTGAGCCCATTCAGATGGCCATCGTTGGGCGTCCCAACGT
TGGTAAAAGCAGCCTGCTCAACACCGTCTGTGGTGAGAACAGGGCCATCGTCAGCCCCATTCGCGGCACCACCCGCGACA
CGATTGACACCAGCATCGAGAGGGAGGGCCAGAGCTGGAAGCTTCTCGATACCGCCGGCATTCGCCGTCGCCGCAGCGTC
AACTACGGTCCGGAGTTTTTTGGCATCAACCGCAGCTTCAAAGCCATCGAGCGCAGCGATGTTTGTGTGCTGGTGATTGA
CGCCGAAGAGGGTGTCACCGAGCAGGACCAGCGCCTGGCAGGCCGCATTGAAGAGGAGGGCCGGGCCTGCCTGGTGGTGG
TCAACAAGTGGGACTTGGTGGAGAAGGACAGCCACACCATGCCGGCGATGGAGAAGGAGCTGCGCAGCAAGCTCTATTTC
CTTGAGTGGGCTCCGATGCTGTTCATCTCAGCGCTCACGGGCCAGCGGGTGGAGCGCATCTTCCCCTTGGCCGTGCTGGC
GGTGGAACAGCACCGCCGCCGCGTCACCACGGCAGTGGTCAATGAGGTGCTGCAGGAGGCCTTGAGTTGGCGTAGCCCTC
CCACCACTCGGGGCGGCCGGCAAGGGCGGCTGTATTACGGCACCCAGGTGGCAGTGCGACCACCCAGCTTCACGTTGTTC
GTCAACGAGCCCAAACTATTTGGCGACACCTACCGCCGTTACGTGGAGCGCCAGATCCGCCAGGGCCTTGGTTTTGAGGG
TTCCCCCGTGCGCCTGTTTTGGCGTGGCAAGCAACAACGGGATGCTGAACGGGATCAGGCCCGTGCTGCCAGCCGCTAA

Upstream 100 bases:

>100_bases
TTGATTATTATTCTGTGAGCGAAAAATAGTTCCAGTGGCTGAGCCCGCTTAGGGCCGGCCTGTAGGGTTTAAACAACGTA
AAAACGAGAGGAACGCAGCC

Downstream 100 bases:

>100_bases
TGGATTGGCTGCGGCAGCTCCCCCTGGGCCAGTACGTGGCTGGTCGCCGCGGTTGGCTGCGGCGTCTTGATCCCAGGCTC
AAATACGCCTGGAGCTTGGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MALPVVAIIGRPNVGKSTLVNRLCRSRDAIVHDEPGVTRDRTYQEGFWGGRTFRVVDTGGLVFDDDSEFLPEIREQASLA
MAEACVALVIVDGQQGLTAADEAIAAWLRQQKCPVLLGVNKCESPEQGLAMAAEFWALGLGEPKPISAIHGAGTGDLLDQ
VLDFLPPQDEEEAPEPIQMAIVGRPNVGKSSLLNTVCGENRAIVSPIRGTTRDTIDTSIEREGQSWKLLDTAGIRRRRSV
NYGPEFFGINRSFKAIERSDVCVLVIDAEEGVTEQDQRLAGRIEEEGRACLVVVNKWDLVEKDSHTMPAMEKELRSKLYF
LEWAPMLFISALTGQRVERIFPLAVLAVEQHRRRVTTAVVNEVLQEALSWRSPPTTRGGRQGRLYYGTQVAVRPPSFTLF
VNEPKLFGDTYRRYVERQIRQGLGFEGSPVRLFWRGKQQRDAERDQARAASR

Sequences:

>Translated_452_residues
MALPVVAIIGRPNVGKSTLVNRLCRSRDAIVHDEPGVTRDRTYQEGFWGGRTFRVVDTGGLVFDDDSEFLPEIREQASLA
MAEACVALVIVDGQQGLTAADEAIAAWLRQQKCPVLLGVNKCESPEQGLAMAAEFWALGLGEPKPISAIHGAGTGDLLDQ
VLDFLPPQDEEEAPEPIQMAIVGRPNVGKSSLLNTVCGENRAIVSPIRGTTRDTIDTSIEREGQSWKLLDTAGIRRRRSV
NYGPEFFGINRSFKAIERSDVCVLVIDAEEGVTEQDQRLAGRIEEEGRACLVVVNKWDLVEKDSHTMPAMEKELRSKLYF
LEWAPMLFISALTGQRVERIFPLAVLAVEQHRRRVTTAVVNEVLQEALSWRSPPTTRGGRQGRLYYGTQVAVRPPSFTLF
VNEPKLFGDTYRRYVERQIRQGLGFEGSPVRLFWRGKQQRDAERDQARAASR
>Mature_451_residues
ALPVVAIIGRPNVGKSTLVNRLCRSRDAIVHDEPGVTRDRTYQEGFWGGRTFRVVDTGGLVFDDDSEFLPEIREQASLAM
AEACVALVIVDGQQGLTAADEAIAAWLRQQKCPVLLGVNKCESPEQGLAMAAEFWALGLGEPKPISAIHGAGTGDLLDQV
LDFLPPQDEEEAPEPIQMAIVGRPNVGKSSLLNTVCGENRAIVSPIRGTTRDTIDTSIEREGQSWKLLDTAGIRRRRSVN
YGPEFFGINRSFKAIERSDVCVLVIDAEEGVTEQDQRLAGRIEEEGRACLVVVNKWDLVEKDSHTMPAMEKELRSKLYFL
EWAPMLFISALTGQRVERIFPLAVLAVEQHRRRVTTAVVNEVLQEALSWRSPPTTRGGRQGRLYYGTQVAVRPPSFTLFV
NEPKLFGDTYRRYVERQIRQGLGFEGSPVRLFWRGKQQRDAERDQARAASR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=40.1287553648069, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=40.8602150537634, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788919, Length=165, Percent_Identity=30.9090909090909, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=133, Percent_Identity=36.0902255639098, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=191, Percent_Identity=31.9371727748691, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SYNR3 (A5GR60)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001226722.1
- ProteinModelPortal:   A5GR60
- SMR:   A5GR60
- STRING:   A5GR60
- GeneID:   5157383
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_0466
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00449
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50400; Mature: 50269

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPVVAIIGRPNVGKSTLVNRLCRSRDAIVHDEPGVTRDRTYQEGFWGGRTFRVVDTGG
CCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCCCCCEEEEEECCC
LVFDDDSEFLPEIREQASLAMAEACVALVIVDGQQGLTAADEAIAAWLRQQKCPVLLGVN
EEECCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECC
KCESPEQGLAMAAEFWALGLGEPKPISAIHGAGTGDLLDQVLDFLPPQDEEEAPEPIQMA
CCCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
IVGRPNVGKSSLLNTVCGENRAIVSPIRGTTRDTIDTSIEREGQSWKLLDTAGIRRRRSV
EECCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHCCHHHCCC
NYGPEFFGINRSFKAIERSDVCVLVIDAEEGVTEQDQRLAGRIEEEGRACLVVVNKWDLV
CCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
EKDSHTMPAMEKELRSKLYFLEWAPMLFISALTGQRVERIFPLAVLAVEQHRRRVTTAVV
CCCCCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLQEALSWRSPPTTRGGRQGRLYYGTQVAVRPPSFTLFVNEPKLFGDTYRRYVERQIR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHH
QGLGFEGSPVRLFWRGKQQRDAERDQARAASR
HCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALPVVAIIGRPNVGKSTLVNRLCRSRDAIVHDEPGVTRDRTYQEGFWGGRTFRVVDTGG
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCCCCCEEEEEECCC
LVFDDDSEFLPEIREQASLAMAEACVALVIVDGQQGLTAADEAIAAWLRQQKCPVLLGVN
EEECCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECC
KCESPEQGLAMAAEFWALGLGEPKPISAIHGAGTGDLLDQVLDFLPPQDEEEAPEPIQMA
CCCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
IVGRPNVGKSSLLNTVCGENRAIVSPIRGTTRDTIDTSIEREGQSWKLLDTAGIRRRRSV
EECCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHCCHHHCCC
NYGPEFFGINRSFKAIERSDVCVLVIDAEEGVTEQDQRLAGRIEEEGRACLVVVNKWDLV
CCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
EKDSHTMPAMEKELRSKLYFLEWAPMLFISALTGQRVERIFPLAVLAVEQHRRRVTTAVV
CCCCCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLQEALSWRSPPTTRGGRQGRLYYGTQVAVRPPSFTLFVNEPKLFGDTYRRYVERQIR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHH
QGLGFEGSPVRLFWRGKQQRDAERDQARAASR
HCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA