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The map label for this gene is kdsA [H]

Identifier: 148241384

GI number: 148241384

Start: 284750

End: 285586

Strand: Direct

Name: kdsA [H]

Synonym: SynRCC307_0285

Alternate gene names: 148241384

Gene position: 284750-285586 (Clockwise)

Preceding gene: 148241383

Following gene: 148241385

Centisome position: 12.8

GC content: 62.25

Gene sequence:

>837_bases
ATGAGCATCCCGTTCACCTTGATTGCTGGGCCCTGTGTGCTCGAAAGCCCTGAGCTGGTTTTTGACATGGCCGCCGCACT
CAAGGCCATGAGCGAGCGGCTCGGTATCCGTTTGTTGTTTAAAACCAGCTTTGACAAGGCCAACCGCAGTTCAGGCGGCA
GTTTCCGCGGTCCCGGCATGGAGCAGGGCCTTGAGGTGCTGGCCCAACTAAAGCAAGAGCTGGGAGTGCAGCTGCTGACC
GATATCCATGAGAGCCACCAGGCTGCCGTGGTGGCTCAGGTGGTGGATGTTTTGCAGATTCCTGCCTTCCTATGTCGCCA
AACCGATCTGCTTTTGGCAGCAGCTGCCGCCGTTCAAAACCCAGAGGCAGCCGCCTCGGTGGTGAATGTCAAAAAAGGGC
AATTCCTCGCCCCCTGGGACATGGCCCAGGTGGTGAGCAAGTTGCGTGAGGCCGGCCTGCAGAGCCCTGAGCAGCTCTGG
CTGACGGAGCGCGGAACCACCTTTGGCTACAACACCTTGGTGGTGGACATGCGCAGCCTGCCGCAGCTGCGCCAGCAGGG
CTGCCCTGTGATTTTTGATGCCACCCACTCGGTGCAACAGCCCGGTGGTCGCGGCAGCAGCACCGGCGGGCAGCGCGAGT
TTGTCGCTCCCTTGGCCCGAGCAGCCATGGCGGTTGGAGTTGATGGGCTGTTCATCGAGACCCACCCCGATCCGGATCAG
GCCCTGAGCGATGGGCCCAACATGGTGCCGTTGCATCGCCTCGAACCTCTGCTGGAGCAGCTATTGGCGATTCGCGCAGC
CGCCGCAGCGCAGCCGGAGGCCGTCAGCAGCCTGTGA

Upstream 100 bases:

>100_bases
CGGTCAGTGGGGAGTTGGTGGGGCTGCTGCGCTTGCATGATCTGGTGCAGGCCGGGCTGAGCCGCGCTTCAGGAACCACA
ACAGACATTCCGCAGGCGGC

Downstream 100 bases:

>100_bases
GCCGCCTCAGTCAGTCGCTACGTGGGCTTGAGTTGCTGGTGCTGGATGTGGATGGTGTCCTCACCGATGGTGGCTTGAGT
TATGCCCCCGATGGCCAGGT

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSIPFTLIAGPCVLESPELVFDMAAALKAMSERLGIRLLFKTSFDKANRSSGGSFRGPGMEQGLEVLAQLKQELGVQLLT
DIHESHQAAVVAQVVDVLQIPAFLCRQTDLLLAAAAAVQNPEAAASVVNVKKGQFLAPWDMAQVVSKLREAGLQSPEQLW
LTERGTTFGYNTLVVDMRSLPQLRQQGCPVIFDATHSVQQPGGRGSSTGGQREFVAPLARAAMAVGVDGLFIETHPDPDQ
ALSDGPNMVPLHRLEPLLEQLLAIRAAAAAQPEAVSSL

Sequences:

>Translated_278_residues
MSIPFTLIAGPCVLESPELVFDMAAALKAMSERLGIRLLFKTSFDKANRSSGGSFRGPGMEQGLEVLAQLKQELGVQLLT
DIHESHQAAVVAQVVDVLQIPAFLCRQTDLLLAAAAAVQNPEAAASVVNVKKGQFLAPWDMAQVVSKLREAGLQSPEQLW
LTERGTTFGYNTLVVDMRSLPQLRQQGCPVIFDATHSVQQPGGRGSSTGGQREFVAPLARAAMAVGVDGLFIETHPDPDQ
ALSDGPNMVPLHRLEPLLEQLLAIRAAAAAQPEAVSSL
>Mature_277_residues
SIPFTLIAGPCVLESPELVFDMAAALKAMSERLGIRLLFKTSFDKANRSSGGSFRGPGMEQGLEVLAQLKQELGVQLLTD
IHESHQAAVVAQVVDVLQIPAFLCRQTDLLLAAAAAVQNPEAAASVVNVKKGQFLAPWDMAQVVSKLREAGLQSPEQLWL
TERGTTFGYNTLVVDMRSLPQLRQQGCPVIFDATHSVQQPGGRGSSTGGQREFVAPLARAAMAVGVDGLFIETHPDPDQA
LSDGPNMVPLHRLEPLLEQLLAIRAAAAAQPEAVSSL

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=265, Percent_Identity=48.3018867924528, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29681; Mature: 29549

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPFTLIAGPCVLESPELVFDMAAALKAMSERLGIRLLFKTSFDKANRSSGGSFRGPGM
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCH
EQGLEVLAQLKQELGVQLLTDIHESHQAAVVAQVVDVLQIPAFLCRQTDLLLAAAAAVQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEAAASVVNVKKGQFLAPWDMAQVVSKLREAGLQSPEQLWLTERGTTFGYNTLVVDMRSL
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHH
PQLRQQGCPVIFDATHSVQQPGGRGSSTGGQREFVAPLARAAMAVGVDGLFIETHPDPDQ
HHHHHCCCCEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
ALSDGPNMVPLHRLEPLLEQLLAIRAAAAAQPEAVSSL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
SIPFTLIAGPCVLESPELVFDMAAALKAMSERLGIRLLFKTSFDKANRSSGGSFRGPGM
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCH
EQGLEVLAQLKQELGVQLLTDIHESHQAAVVAQVVDVLQIPAFLCRQTDLLLAAAAAVQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEAAASVVNVKKGQFLAPWDMAQVVSKLREAGLQSPEQLWLTERGTTFGYNTLVVDMRSL
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHH
PQLRQQGCPVIFDATHSVQQPGGRGSSTGGQREFVAPLARAAMAVGVDGLFIETHPDPDQ
HHHHHCCCCEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
ALSDGPNMVPLHRLEPLLEQLLAIRAAAAAQPEAVSSL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA