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The map label for this gene is holB [H]

Identifier: 148241354

GI number: 148241354

Start: 253771

End: 254703

Strand: Direct

Name: holB [H]

Synonym: SynRCC307_0255

Alternate gene names: 148241354

Gene position: 253771-254703 (Clockwise)

Preceding gene: 148241353

Following gene: 148241358

Centisome position: 11.41

GC content: 63.02

Gene sequence:

>933_bases
GTGAGTGAGGCGCTGTTCGCCGGAATCGAAGGGCAGCAGCAGGCCCTTGAGCTGCTCACTGCTGCTTTGAATCAGCAGCG
CCTGGCCCCGGCTTATCTGTTTGCCGGGCCCGATGGCGTGGGGCGCTCCTTAACGGCCCGCCGTTTTCTCGAAGGCCTTT
GCGCTGGTGGCGCGCAGCCCGATCCGGACTTGCGACGCAGGCTGCAACAGGGCAACCATCCCGATTTGATCTGGGTGGAG
CCCACCTATTTGGAGAAAGGCGAGCGCATCACGGCGACGGAAGCCAAAGAGCGTGGCTTGAGCAAGAAAACCCTGCCCCA
GATCCGCTTGGAGCAGATCCGTGAAGTCAGCCGTTTTTTGGCGCGGCCGCCCCTGGATGCCAGCCGCTCCATGGTCGTGA
TTGAGCAGGCTGAGGCGATGGCTGAGTCTGCAGCCAATGCCCTGCTGAAAACCTTGGAGGAGCCTGGCCAGGGCCTGCTT
GTGTTGATCACCGCAGCCCCCGAGCGCCTGTTGGCCACGATCTTGAGCCGTTGTCAGCGCATCCCCTTTAAGCCATTGCC
GGCTCACACGATGCTGCAGCTGGTGGGCGGCGCCCAAGACGATCCCCCGGCGCTGGTGGATTTAGCGGCTGGGTCCCCTG
GCGCCTTGCTTTTGTGGCGTGAGCGTTGGGCCGAACTGCCGCCTGAGCTGTTGGCCCAGCTGCAGCAACTCCCCACCCAG
CCGATCGATGCGCTCACTTTGGCCCGTGAGGTGTGTGAAGCGCTCGACACCGAGCAGCAGCTCTGGTTATTGCAGTGGTG
GCAATGGCACCTTTGGCGCCAGCAAGCCCAAGACAACGTGCAGCGGAGGCTGACCAAGCTGCGCCGCCATTTGGTTGGAC
ACGTTCAACCGCGGTTGGCTTGGGAAGTGGCCTTGCTGGATCTGATCGCCTAA

Upstream 100 bases:

>100_bases
GCCAGCGGCCGCTTTGGCGGCGGGTGGATGCCTCGCTTCCCCCTGAGCAGGTGCATCAGCAGGTGCAGCACTTGGTGCGT
GAGGGTTTGGAGTTGGCCCT

Downstream 100 bases:

>100_bases
GCGATCTGCTCGAGGTTGCCCTGGCGCTCGGCGCGGAACTCTTTCATCACGCGGCTGGAGTCATCGAGGTTGGCTCCACT
GGGAAGCTCCAGGCAATAGC

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSEALFAGIEGQQQALELLTAALNQQRLAPAYLFAGPDGVGRSLTARRFLEGLCAGGAQPDPDLRRRLQQGNHPDLIWVE
PTYLEKGERITATEAKERGLSKKTLPQIRLEQIREVSRFLARPPLDASRSMVVIEQAEAMAESAANALLKTLEEPGQGLL
VLITAAPERLLATILSRCQRIPFKPLPAHTMLQLVGGAQDDPPALVDLAAGSPGALLLWRERWAELPPELLAQLQQLPTQ
PIDALTLAREVCEALDTEQQLWLLQWWQWHLWRQQAQDNVQRRLTKLRRHLVGHVQPRLAWEVALLDLIA

Sequences:

>Translated_310_residues
MSEALFAGIEGQQQALELLTAALNQQRLAPAYLFAGPDGVGRSLTARRFLEGLCAGGAQPDPDLRRRLQQGNHPDLIWVE
PTYLEKGERITATEAKERGLSKKTLPQIRLEQIREVSRFLARPPLDASRSMVVIEQAEAMAESAANALLKTLEEPGQGLL
VLITAAPERLLATILSRCQRIPFKPLPAHTMLQLVGGAQDDPPALVDLAAGSPGALLLWRERWAELPPELLAQLQQLPTQ
PIDALTLAREVCEALDTEQQLWLLQWWQWHLWRQQAQDNVQRRLTKLRRHLVGHVQPRLAWEVALLDLIA
>Mature_309_residues
SEALFAGIEGQQQALELLTAALNQQRLAPAYLFAGPDGVGRSLTARRFLEGLCAGGAQPDPDLRRRLQQGNHPDLIWVEP
TYLEKGERITATEAKERGLSKKTLPQIRLEQIREVSRFLARPPLDASRSMVVIEQAEAMAESAANALLKTLEEPGQGLLV
LITAAPERLLATILSRCQRIPFKPLPAHTMLQLVGGAQDDPPALVDLAAGSPGALLLWRERWAELPPELLAQLQQLPTQP
IDALTLAREVCEALDTEQQLWLLQWWQWHLWRQQAQDNVQRRLTKLRRHLVGHVQPRLAWEVALLDLIA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=187, Percent_Identity=29.9465240641711, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 34651; Mature: 34519

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALFAGIEGQQQALELLTAALNQQRLAPAYLFAGPDGVGRSLTARRFLEGLCAGGAQP
CCCCHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
DPDLRRRLQQGNHPDLIWVEPTYLEKGERITATEAKERGLSKKTLPQIRLEQIREVSRFL
CHHHHHHHHCCCCCCEEEECCHHHHCCCEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ARPPLDASRSMVVIEQAEAMAESAANALLKTLEEPGQGLLVLITAAPERLLATILSRCQR
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHC
IPFKPLPAHTMLQLVGGAQDDPPALVDLAAGSPGALLLWRERWAELPPELLAQLQQLPTQ
CCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCC
PIDALTLAREVCEALDTEQQLWLLQWWQWHLWRQQAQDNVQRRLTKLRRHLVGHVQPRLA
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
WEVALLDLIA
HHHHHHHHHC
>Mature Secondary Structure 
SEALFAGIEGQQQALELLTAALNQQRLAPAYLFAGPDGVGRSLTARRFLEGLCAGGAQP
CCCHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
DPDLRRRLQQGNHPDLIWVEPTYLEKGERITATEAKERGLSKKTLPQIRLEQIREVSRFL
CHHHHHHHHCCCCCCEEEECCHHHHCCCEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ARPPLDASRSMVVIEQAEAMAESAANALLKTLEEPGQGLLVLITAAPERLLATILSRCQR
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHC
IPFKPLPAHTMLQLVGGAQDDPPALVDLAAGSPGALLLWRERWAELPPELLAQLQQLPTQ
CCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCC
PIDALTLAREVCEALDTEQQLWLLQWWQWHLWRQQAQDNVQRRLTKLRRHLVGHVQPRLA
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
WEVALLDLIA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]