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The map label for this gene is moaC

Identifier: 147675618

GI number: 147675618

Start: 585450

End: 585932

Strand: Direct

Name: moaC

Synonym: VC0395_A0546

Alternate gene names: 147675618

Gene position: 585450-585932 (Clockwise)

Preceding gene: 147673390

Following gene: 147674797

Centisome position: 19.36

GC content: 51.55

Gene sequence:

>483_bases
TTGATGAGCCAACTCACTCATATTAATGCTTCGGGTGAAGCCAATATGGTGGATGTGTCGAATAAAGCCGATACTGTCCG
TGAAGCTCGTGCCGAGGCCTATGTGCGCATGGCACCCGAAACGCTGCAACTCATCCTCTCTGGCCAGCACCATAAAGGGG
ATGTGTTTGCCACTGCGCGTATTGCGGGCATTCAAGCCGCGAAACGTACGTGGGAGCTTATTCCGCTCTGTCACCCGTTG
CTGCTTTCCAAGGTGGAAGTACAGCTTGAAGCCTTGCCAGAACAAAGCAGCGTACGCATTGAATCTCTGTGTAAACTCAG
TGGTAAAACCGGGGTGGAAATGGAAGCGCTGACGGCGGCATCGGTGGCGGCACTGACCATTTACGACATGTGCAAAGCGG
TTCAAAAAGACATCGTAATTGAGAACGTGCGATTGCTTGAAAAATCGGGCGGAAAATCGGGACACTTTAAGGTGGATGCA
TGA

Upstream 100 bases:

>100_bases
GGCGCATGCCGCACCGGTTGGACAAAAATCATTAAACAGCAATTGGATGCTTCCCATCGCCCATGTAACTTTATGCCGCA
CCTAACGGTATAGGGGAGGT

Downstream 100 bases:

>100_bases
TTAAGGTGCTGTTTTTTGCCCAAACTCGAGAGTTGGTGGAGTGCGATAGTCTGGTGGTTGACCACGCTTTTGCAACGGTA
GAAGCTTTGCGCCAACATTT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPL
LLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA

Sequences:

>Translated_160_residues
MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPL
LLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA
>Mature_160_residues
MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPL
LLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=159, Percent_Identity=81.1320754716981, Blast_Score=266, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=43.046357615894, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=61.3333333333333, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=62.043795620438, Blast_Score=160, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_VIBC3 (A5F2Q7)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F2Q7
- SMR:   A5F2Q7
- STRING:   A5F2Q7
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0546
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   VCHO345073:VC0395_A0546-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17340; Mature: 17340

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATAR
CCCCCCEECCCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHH
IAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATAR
CCCCCCEECCCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHH
IAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA