Click here to switch to the map view.

The map label for this gene is moaB [H]

Identifier: 147673390

GI number: 147673390

Start: 584930

End: 585442

Strand: Direct

Name: moaB [H]

Synonym: VC0395_A0545

Alternate gene names: 147673390

Gene position: 584930-585442 (Clockwise)

Preceding gene: 147674357

Following gene: 147675618

Centisome position: 19.34

GC content: 49.71

Gene sequence:

>513_bases
ATGGGTCACGCAGAAAGCAAATTTCAAGCAGCAAACATCGCCGTTTTAACCGTGTCAGATACGCGCACGGAAGAAAACGA
TACCTCAGGCCGTTACTTGGCAGAGCAGCTTCAAGAAGCTGGCCATACACTGGCAGATAAACAGATCGTGATTGACGATA
TGTACAAAATCCGTGCGGTGGTTTCACAGTGGATTGCGGATGAAACCATCCAAGCGATTCTGATCACCGGTGGCACTGGG
TTTACGTCACGTGACAGCACACCTGAAGCACTTAAGCCTCTGTTTGATAAAGAAGTGGAAGGTTTTGGCGAGCTGTTTCG
CATGGTCTCTTTTGAAGAGATTGGCACCTCGACCATTCAATCGCGCGCGGTTGCGGGGTTTGCTAACCACACGGTGATTT
TTGCTATGCCGGGTTCGACTGGCGCATGCCGCACCGGTTGGACAAAAATCATTAAACAGCAATTGGATGCTTCCCATCGC
CCATGTAACTTTATGCCGCACCTAACGGTATAG

Upstream 100 bases:

>100_bases
ATTCGGGTGTGACGCCGCATTTAGCCTCGATTGGCGGCTGAGTTTCTACCGATAATCTGACCTCACCATTGAGGTTTAAC
CATTTTGAAAAGGTGAACAA

Downstream 100 bases:

>100_bases
GGGAGGTTTGATGAGCCAACTCACTCATATTAATGCTTCGGGTGAAGCCAATATGGTGGATGTGTCGAATAAAGCCGATA
CTGTCCGTGAAGCTCGTGCC

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MGHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAVVSQWIADETIQAILITGGTG
FTSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQSRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHR
PCNFMPHLTV

Sequences:

>Translated_170_residues
MGHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAVVSQWIADETIQAILITGGTG
FTSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQSRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHR
PCNFMPHLTV
>Mature_169_residues
GHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAVVSQWIADETIQAILITGGTGF
TSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQSRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHRP
CNFMPHLTV

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=132, Percent_Identity=35.6060606060606, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI66932975, Length=132, Percent_Identity=35.6060606060606, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787000, Length=168, Percent_Identity=64.8809523809524, Blast_Score=229, Evalue=8e-62,
Organism=Drosophila melanogaster, GI17136978, Length=149, Percent_Identity=35.5704697986577, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=149, Percent_Identity=35.5704697986577, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18637; Mature: 18506

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAV
CCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHH
VSQWIADETIQAILITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQ
HHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHRPCNFMPHLTV
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAV
CCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHH
VSQWIADETIQAILITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQ
HHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHRPCNFMPHLTV
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]