Click here to switch to the map view.

The map label for this gene is cysC [H]

Identifier: 147675279

GI number: 147675279

Start: 2292340

End: 2292987

Strand: Reverse

Name: cysC [H]

Synonym: VC0395_A2135

Alternate gene names: 147675279

Gene position: 2292987-2292340 (Counterclockwise)

Preceding gene: 147673489

Following gene: 147673985

Centisome position: 75.82

GC content: 53.4

Gene sequence:

>648_bases
ATGAGTAAGCAAGCAGATAGCCTGCGCTTTGAACAAGATGCCAAGCTAGAGAATGTGGTGTGGCATCGTCATGCGGTGGA
TAAAGCGCAACGTGCGGCACTGAAACAGCAGCGCCCTGCGGTACTCTGGTTTACCGGTTTATCGGGTGCGGGCAAATCGA
CCGTGGCAGGGGCGCTTGAGAACCGTTTAGCGGCGCTTGGGTATCACACTTATCTGCTGGATGGTGATAACGTGCGCCAC
GGTTTGTGTAGCGATCTCGGCTTTTCTGAGCAGGATAGACGGGAAAACATTCGCCGCATTGGTGAGCTTGCCAAACTGAT
GGCGGATGCGGGTTTGATTGTGCTGACCGCGTTTATTTCACCCCATCGCGCTGAGCGCCAAATGGTGCGTGACTTGTTGC
CAAATGGCGAGTTTCTAGAGGTGTACGTCAACACATCACTCGATGTGTGCGAAGCGCGTGACCCGAAAGGCTTGTACAAA
AAGGCGCGCGCCGGAGAAATTCGCCAATTTACTGGGATTGATTCCGCCTATGAAGCGCCGCTCAATCCGGATATCGATTT
ACCGGTGGGTGAAAAAAGCGTGGATGAGTTGGTGGCGCAGTGCCTTCAGGCGTTAGCAGAGCGTCATATCATTCAACGTT
GGGTATAA

Upstream 100 bases:

>100_bases
TCAGCCTTTGAACTTGAGCTCAATGCCTTGGTGCGTAAGCACTTCCCACATTGGCAAGCGATTGATTTAAGCCGCTTAGG
TAAAGCGTGAGTGAGGATGG

Downstream 100 bases:

>100_bases
CTCTTTAGATTCAAAATAAACCAAAAGCGACCGTCCGGTCGCTTTTTTGATCTCTTTATTGAGGGCATGTCATCAGACGG
TGTGGTGAATCGAGCTGCTG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSKQADSLRFEQDAKLENVVWHRHAVDKAQRAALKQQRPAVLWFTGLSGAGKSTVAGALENRLAALGYHTYLLDGDNVRH
GLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLTAFISPHRAERQMVRDLLPNGEFLEVYVNTSLDVCEARDPKGLYK
KARAGEIRQFTGIDSAYEAPLNPDIDLPVGEKSVDELVAQCLQALAERHIIQRWV

Sequences:

>Translated_215_residues
MSKQADSLRFEQDAKLENVVWHRHAVDKAQRAALKQQRPAVLWFTGLSGAGKSTVAGALENRLAALGYHTYLLDGDNVRH
GLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLTAFISPHRAERQMVRDLLPNGEFLEVYVNTSLDVCEARDPKGLYK
KARAGEIRQFTGIDSAYEAPLNPDIDLPVGEKSVDELVAQCLQALAERHIIQRWV
>Mature_214_residues
SKQADSLRFEQDAKLENVVWHRHAVDKAQRAALKQQRPAVLWFTGLSGAGKSTVAGALENRLAALGYHTYLLDGDNVRHG
LCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLTAFISPHRAERQMVRDLLPNGEFLEVYVNTSLDVCEARDPKGLYKK
ARAGEIRQFTGIDSAYEAPLNPDIDLPVGEKSVDELVAQCLQALAERHIIQRWV

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=203, Percent_Identity=49.2610837438424, Blast_Score=187, Evalue=5e-48,
Organism=Homo sapiens, GI34447231, Length=209, Percent_Identity=46.88995215311, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI62912492, Length=209, Percent_Identity=46.88995215311, Blast_Score=187, Evalue=8e-48,
Organism=Escherichia coli, GI1789107, Length=196, Percent_Identity=67.3469387755102, Blast_Score=264, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17542422, Length=200, Percent_Identity=51, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6322852, Length=198, Percent_Identity=47.4747474747475, Blast_Score=188, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24667032, Length=222, Percent_Identity=41.8918918918919, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667028, Length=222, Percent_Identity=41.8918918918919, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667036, Length=222, Percent_Identity=41.8918918918919, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667040, Length=216, Percent_Identity=42.5925925925926, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI116007838, Length=202, Percent_Identity=43.5643564356436, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24667044, Length=202, Percent_Identity=43.5643564356436, Blast_Score=167, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 24004; Mature: 23872

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQADSLRFEQDAKLENVVWHRHAVDKAQRAALKQQRPAVLWFTGLSGAGKSTVAGALE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
NRLAALGYHTYLLDGDNVRHGLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLTAFIS
HHHHHHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
PHRAERQMVRDLLPNGEFLEVYVNTSLDVCEARDPKGLYKKARAGEIRQFTGIDSAYEAP
CCHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCCHHHHHHHHCCCHHHHHCCCHHHCCC
LNPDIDLPVGEKSVDELVAQCLQALAERHIIQRWV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKQADSLRFEQDAKLENVVWHRHAVDKAQRAALKQQRPAVLWFTGLSGAGKSTVAGALE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
NRLAALGYHTYLLDGDNVRHGLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLTAFIS
HHHHHHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
PHRAERQMVRDLLPNGEFLEVYVNTSLDVCEARDPKGLYKKARAGEIRQFTGIDSAYEAP
CCHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCCHHHHHHHHCCCHHHHHCCCHHHCCC
LNPDIDLPVGEKSVDELVAQCLQALAERHIIQRWV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]