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The map label for this gene is tdk

Identifier: 147674995

GI number: 147674995

Start: 764600

End: 765178

Strand: Direct

Name: tdk

Synonym: VC0395_A0736

Alternate gene names: 147674995

Gene position: 764600-765178 (Clockwise)

Preceding gene: 147674215

Following gene: 147673724

Centisome position: 25.28

GC content: 48.88

Gene sequence:

>579_bases
TTGGCTCAGATGTACTTTTATTACTCGGCAATGAATGCGGGTAAGTCGACCACCTTATTGCAATCGGCGTTTAACTACCA
AGAACGCGGCATGAACCCACTGATTTTTACCGCCGCGATCGACGATCGGTTTGGTGTTGGCAAAGTGAGTTCTCGGATTG
GGCTTGAGGCCGAAGCGCACCTTTTCCATGCCGATACCGATCTGTTGCACGTGATCGCAACATTGCATGAGGCTGAACCT
CGTCACTGTATTTTGATGGATGAGTGTCAGTTTCTCTCTAAAGAGCAGGTTTACCAACTGACCGAAGTAGTGGATAAACT
GGATATCCCTGTGCTGTGTTACGGCTTGCGTACCGATTTTCTCGGTGAGCTGTTTGAAGGCAGTAAATATCTACTCTCAT
GGGCGGATAAACTGATTGAGCTGAAAACCATTTGCCACTGTGGACGCAAAGCCAACATGGTGATCCGTACCGATGAGCAT
GGCAACGCCATCAGCGAAGGGGATCAGGTGGCGATTGGCGGTAATGATAAGTATGTTTCAGTCTGTCGCCAGCACTATAA
AGAGGCGTTGGGACGCTAA

Upstream 100 bases:

>100_bases
GTAATCAACGCCTTGCAAAGGGTGGCATTAGCCACCCTTTTTTTTAACCTGCGCGGCACGAGAGCGCAGACAGTAAAATG
ATACAAACAGGATTTCTTCT

Downstream 100 bases:

>100_bases
GCGAACCCATCTCCTTCGCGGGATAATTTGCCCGTGACTCAATAAAGAAAAAGCCAGACAGTTAATGTCTGGCTTTTTTT
ATGAATGATAATGATCAGCG

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAHLFHADTDLLHVIATLHEAEP
RHCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDFLGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEH
GNAISEGDQVAIGGNDKYVSVCRQHYKEALGR

Sequences:

>Translated_192_residues
MAQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAHLFHADTDLLHVIATLHEAEP
RHCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDFLGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEH
GNAISEGDQVAIGGNDKYVSVCRQHYKEALGR
>Mature_191_residues
AQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAHLFHADTDLLHVIATLHEAEPR
HCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDFLGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEHG
NAISEGDQVAIGGNDKYVSVCRQHYKEALGR

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=68.9473684210526, Blast_Score=290, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_VIBCH (Q9KST9)

Other databases:

- EMBL:   AE003852
- PIR:   B82232
- RefSeq:   NP_230812.1
- ProteinModelPortal:   Q9KST9
- SMR:   Q9KST9
- GeneID:   2614600
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1167
- TIGR:   VC_1167
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- ProtClustDB:   PRK04296
- BRENDA:   2.7.1.21
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21659; Mature: 21528

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAH
CCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCCCCCHHE
LFHADTDLLHVIATLHEAEPRHCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDF
EEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHH
LGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEHGNAISEGDQVAIGGNDKYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHH
VCRQHYKEALGR
HHHHHHHHHHCC
>Mature Secondary Structure 
AQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAH
CEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCCCCCHHE
LFHADTDLLHVIATLHEAEPRHCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDF
EEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHH
LGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEHGNAISEGDQVAIGGNDKYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHH
VCRQHYKEALGR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301