| Definition | Vibrio cholerae O395 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_009457 |
| Length | 3,024,069 |
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The map label for this gene is uvrA [H]
Identifier: 147674724
GI number: 147674724
Start: 2959741
End: 2962563
Strand: Reverse
Name: uvrA [H]
Synonym: VC0395_A2812
Alternate gene names: 147674724
Gene position: 2962563-2959741 (Counterclockwise)
Preceding gene: 147673562
Following gene: 147675121
Centisome position: 97.97
GC content: 48.88
Gene sequence:
>2823_bases ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG TCGAATCACTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCATATTGAGGGGCTTTCA CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACGATTACGGAAGTGTATGACTA TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGCCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC AGATGGTAGACAAAGTATTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC CGATCCACCGAAACTCGAACTGCACAAAAAGCATACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTGGAACTTTCCGGCGGTATCGTCGTTGTCGCCCCGATGGAAGGCGAT GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAACTTGAACCACGCCTGTT CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA TTCAAGATGCCAATTTAAGTTTGGCACAAGGTGCGATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACGCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTTAAAAAACATCCTTTTG AAGGAATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTACGTGAGGAGCTGGCAAAATACATC TCCAACAAGCCTTGCAGCAGCTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGCT GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGTATTCGTCTAGCCAGTCAGATTGGTGCGGGTTTAGTCGGTGT GATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGATGCAAACCCTCACCCACTTAC GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC AGGTCAATATCTCAGTGGCGTGAAAAAAATCGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC TTAAAGGCGCAGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACAGCACTCAATGGCGCGACGACGGC GACACCTGCGCCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC GCACTCCTCGCTCCAACCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTATTTGCAGGAACACAAGAGTCT CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTTAACGTCCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAACGCTATAACCGAGAAA CACTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGATTGTCCTACATTCGTCTTGGGCAATCAGCCAC CACCTTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCGCGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA TTTTGGATGAACCAACCACGGGCCTACACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGACTGGATCATCGATTTAGGCCCCGAAGG CGGCCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT TCCTCAAGCCTTTGTTGAATTAG
Upstream 100 bases:
>100_bases TTTTGCTTTTGATACAACTGTTTTTTTATCCAGTAATTGCTTGCACTTTGTTCACGCTATGTAATACTTGCTGCACTTCG TTTAGCAAAGAGCAACCCAG
Downstream 100 bases:
>100_bases AAAAAAAGGCTAAAGTAATGAAACCAGCGAACTGTGCGCTGGTTTCTTTTTTAAGGTGAACTGCATGGCAACTTTGCTGT TAAGTGGCACTCGGTTGGAA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 940; Mature: 940
Protein sequence:
>940_residues MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLMQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN
Sequences:
>Translated_940_residues MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLMQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN >Mature_940_residues MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLMQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=80.8510638297872, Blast_Score=1588, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104347; Mature: 104347
Theoretical pI: Translated: 6.49; Mature: 6.49
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKGEHVKTLENLAAQGFIRARID CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEC GETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLS CCHHEEECCCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCH LAQGAIRGWDQKNFYYFQMLTALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYI HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE NDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYISNKPCSSCDGTRLKIEARNV CCCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE FINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS EEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEECC RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLMQTLTHLRNLGNTV CCCHHCCCCCHHHHHHHHHHCCCCEEHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCEE LVVEHDEDAIRMADHVIDIGPGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVP EEEECCCHHHHHHHHHEECCCCCCCCCCEEEECCCHHHHHCCCCCCCHHHHHCHHHHCCC EQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGVSGSGKSTLINDTFFKIAHTA CCCCCCHHHHEEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHH LNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHH RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEC GKTIDEVLDMTVEDAREFFDPVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLA CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCHHHHHHH RELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDHGNTVVVIEHNLDVIKTADWI HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEE IDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN EEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKGEHVKTLENLAAQGFIRARID CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEC GETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLS CCHHEEECCCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCH LAQGAIRGWDQKNFYYFQMLTALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYI HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE NDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYISNKPCSSCDGTRLKIEARNV CCCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE FINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS EEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEECC RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLMQTLTHLRNLGNTV CCCHHCCCCCHHHHHHHHHHCCCCEEHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCEE LVVEHDEDAIRMADHVIDIGPGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVP EEEECCCHHHHHHHHHEECCCCCCCCCCEEEECCCHHHHHCCCCCCCHHHHHCHHHHCCC EQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGVSGSGKSTLINDTFFKIAHTA CCCCCCHHHHEEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHH LNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHH RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEC GKTIDEVLDMTVEDAREFFDPVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLA CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCHHHHHHH RELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDHGNTVVVIEHNLDVIKTADWI HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEE IDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN EEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]