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The map label for this gene is hlyB [H]

Identifier: 147674542

GI number: 147674542

Start: 1201076

End: 1203097

Strand: Reverse

Name: hlyB [H]

Synonym: VC0395_A1141

Alternate gene names: 147674542

Gene position: 1203097-1201076 (Counterclockwise)

Preceding gene: 147675224

Following gene: 147673302

Centisome position: 39.78

GC content: 47.68

Gene sequence:

>2022_bases
ATGGCTTTGACAAAAAATTTATCCTTAACCCAAACACTCGGTGCGGTGTTTCTATGCATAACCATACTGATGATTAGCTT
ATCTGTCACCAGTTTACGTGGCATAGAGCGGGTTGGCGCTCAGTTTAATCAACTGTCTGAACAAGCTTTGCCCTTTGCGC
TTAATAATGCAGCGTTAACGCAAAATTTTCTCGAACAAGTGAAGTACCTAGGTTATGGCACTCGTAGCCAATCTGAGCAA
GAGCTCAATCAAGTGCTCAATGAATGGCAAAAGCTGGATGCTCAAGCGGGAGATGAAATAACAAGATTGCAGCAGAACGT
ACAATTGCTCTCTAGCGCTGAAGCGGTTCAACAAGCCGAGCAGTTACAGCGAGAGATCCTTCATTTTCAACAGCTAGCCC
AATCGATTCTCAAACTTCAACAACTGCAATTGAGTAAAACAGCACAAATCAGTGAGCAAGCGAAACAATTTCGTTATGGC
TTGAGTTCAATCGGACCTGAAATGGGCCGTATCGCCTCGTTTTTAGCGGTGGATAACCCAGAAGCCATGGATGCAGCGAA
CCGATTTACCGCCAGTGCCAGCGCAATGGAAAGTGCTTTTTTATTGCTGTTTATCGAAGAAGAGATGTCAGCAGCGCAAA
AATACCGCCAAGAGTTAAAAAATCGGGTAGCGGGATTGGAACTGGCGTTTGATGACTTCAAAGAGTGGTACCCAGAAATT
AAAGATTACGCGAGCTTAACTGCCCCCTATGAAATGGTGTTAGCAGGCTTTCAAGCGCAAGCCGTGATAGAGCAGATCAT
TAATAAACTGGAAGACGCGCAACAACAAAATAAGGATTTTGCAAGCGCTGCAGAGGTTGCGCAGCAACTTGTCACGCAGC
TCAATCAGTGGTCAACATTGGCTCAACAACACATTGTGCAGGGTAAGCAAGAGGTAACATCAACCATTTCTGCCGTCACC
CTCACACAGCAAATCAGCGGCACTCTCTTGGTGCTGGCGATTTTGGCGGTGTGGTTTGGCTTGCGCCGTTGGATAGGGCG
AGCGCTGAACAACATCACTCGTCATCTCGCGCAGTTAACACAACATAAGCTTAACCACAGATTAGATTTAGTCGGGCCGC
AAGATTTTCAAAATGTCGCAGCGCAACTCAATCAAGTGATCGTATCAACGCATGAGTCGCTCGCATTAGTCACGCGCAAC
TGCGAAACGCTCTACCAAACGGCTGAGCTGAGCCATGGTTCCGCAGAACAATCAAACCAAAGCTTAGCGGCGCAAAATCA
AGCCTTGTTGACCATGGCTGCAACCATTAATCAACTGGATGCATCAATTCGCGAAATCGCCGGAGTGAGTCACGATTCGT
ACACGGATTCTGTGGAAGCGGCGGAACATTCCGCGCAAGGTGTGAAGGTGATAGAGCAGAATCAGCAGCGTTTACAAGCA
TTAGAAACCACCTTAGCGGTTAATGATGCGGCGATGTCTGAACTCAATCAGCGCGTAACCAGTATTCGTGAAATGGTGGA
TATGATCAGTGGCATTGCCGATAGCACCAATTTGTTAGCGCTGAATGCGGCGATTGAAGCCGCACGAGCCGGAGAGCAAG
GGCGCGGTTTTGCCGTAGTGGCTGACGAAGTTCGTAAATTGGCCAGTGATACCAGTAAACAGACCACCAATATTCGTGAC
ATGATGAATGAGTTGGTGACTGCGGCCAGTAAATCACGCCAAGCGGTGGATGAATCGCGTAAAGAGATGGTCACCGCCCT
ACAATCGAGTGAAGAAGTAAAAAGTACCTTTATGCAGATTGAGCGTGCAGTGGCACATATTCGCACTCGAGTCGAGCAGA
TCACTCAAGCGACCGAAGAACAAAAGCGAGCCACGGCGGATGTAAACAAAGCGGTAGCGCAAATTTCCGAACAAGGGCAA
GAAACCAAACGTCAGTTGGATGCCATGTTGGAAAGCGCGGAACAAGTCGCAGAGATTGCTGGTCATCAACAAGCGATGTT
GCATAAGTATGAGTTGAACTGA

Upstream 100 bases:

>100_bases
GACCGTCAACATGAGTCACCTTATTGACAAAAAAATGAAATAAAACTGAAACAGCCACTACCTACCATGGCGTCGACTCT
CAAACCTAAGACGCATTTAC

Downstream 100 bases:

>100_bases
TTTAACGTTCGCGAAACGGTTGAGTCAGCATTTTATCCAGCCACTGTTCTCGTGCTTGACGAAACAGTGGCAAGCCAATC
TTCATTCGCTCATGGCCCAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MALTKNLSLTQTLGAVFLCITILMISLSVTSLRGIERVGAQFNQLSEQALPFALNNAALTQNFLEQVKYLGYGTRSQSEQ
ELNQVLNEWQKLDAQAGDEITRLQQNVQLLSSAEAVQQAEQLQREILHFQQLAQSILKLQQLQLSKTAQISEQAKQFRYG
LSSIGPEMGRIASFLAVDNPEAMDAANRFTASASAMESAFLLLFIEEEMSAAQKYRQELKNRVAGLELAFDDFKEWYPEI
KDYASLTAPYEMVLAGFQAQAVIEQIINKLEDAQQQNKDFASAAEVAQQLVTQLNQWSTLAQQHIVQGKQEVTSTISAVT
LTQQISGTLLVLAILAVWFGLRRWIGRALNNITRHLAQLTQHKLNHRLDLVGPQDFQNVAAQLNQVIVSTHESLALVTRN
CETLYQTAELSHGSAEQSNQSLAAQNQALLTMAATINQLDASIREIAGVSHDSYTDSVEAAEHSAQGVKVIEQNQQRLQA
LETTLAVNDAAMSELNQRVTSIREMVDMISGIADSTNLLALNAAIEAARAGEQGRGFAVVADEVRKLASDTSKQTTNIRD
MMNELVTAASKSRQAVDESRKEMVTALQSSEEVKSTFMQIERAVAHIRTRVEQITQATEEQKRATADVNKAVAQISEQGQ
ETKRQLDAMLESAEQVAEIAGHQQAMLHKYELN

Sequences:

>Translated_673_residues
MALTKNLSLTQTLGAVFLCITILMISLSVTSLRGIERVGAQFNQLSEQALPFALNNAALTQNFLEQVKYLGYGTRSQSEQ
ELNQVLNEWQKLDAQAGDEITRLQQNVQLLSSAEAVQQAEQLQREILHFQQLAQSILKLQQLQLSKTAQISEQAKQFRYG
LSSIGPEMGRIASFLAVDNPEAMDAANRFTASASAMESAFLLLFIEEEMSAAQKYRQELKNRVAGLELAFDDFKEWYPEI
KDYASLTAPYEMVLAGFQAQAVIEQIINKLEDAQQQNKDFASAAEVAQQLVTQLNQWSTLAQQHIVQGKQEVTSTISAVT
LTQQISGTLLVLAILAVWFGLRRWIGRALNNITRHLAQLTQHKLNHRLDLVGPQDFQNVAAQLNQVIVSTHESLALVTRN
CETLYQTAELSHGSAEQSNQSLAAQNQALLTMAATINQLDASIREIAGVSHDSYTDSVEAAEHSAQGVKVIEQNQQRLQA
LETTLAVNDAAMSELNQRVTSIREMVDMISGIADSTNLLALNAAIEAARAGEQGRGFAVVADEVRKLASDTSKQTTNIRD
MMNELVTAASKSRQAVDESRKEMVTALQSSEEVKSTFMQIERAVAHIRTRVEQITQATEEQKRATADVNKAVAQISEQGQ
ETKRQLDAMLESAEQVAEIAGHQQAMLHKYELN
>Mature_672_residues
ALTKNLSLTQTLGAVFLCITILMISLSVTSLRGIERVGAQFNQLSEQALPFALNNAALTQNFLEQVKYLGYGTRSQSEQE
LNQVLNEWQKLDAQAGDEITRLQQNVQLLSSAEAVQQAEQLQREILHFQQLAQSILKLQQLQLSKTAQISEQAKQFRYGL
SSIGPEMGRIASFLAVDNPEAMDAANRFTASASAMESAFLLLFIEEEMSAAQKYRQELKNRVAGLELAFDDFKEWYPEIK
DYASLTAPYEMVLAGFQAQAVIEQIINKLEDAQQQNKDFASAAEVAQQLVTQLNQWSTLAQQHIVQGKQEVTSTISAVTL
TQQISGTLLVLAILAVWFGLRRWIGRALNNITRHLAQLTQHKLNHRLDLVGPQDFQNVAAQLNQVIVSTHESLALVTRNC
ETLYQTAELSHGSAEQSNQSLAAQNQALLTMAATINQLDASIREIAGVSHDSYTDSVEAAEHSAQGVKVIEQNQQRLQAL
ETTLAVNDAAMSELNQRVTSIREMVDMISGIADSTNLLALNAAIEAARAGEQGRGFAVVADEVRKLASDTSKQTTNIRDM
MNELVTAASKSRQAVDESRKEMVTALQSSEEVKSTFMQIERAVAHIRTRVEQITQATEEQKRATADVNKAVAQISEQGQE
TKRQLDAMLESAEQVAEIAGHQQAMLHKYELN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=314, Percent_Identity=28.6624203821656, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=29.0969899665552, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI2367378, Length=309, Percent_Identity=28.1553398058252, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788194, Length=338, Percent_Identity=27.5147928994083, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=234, Percent_Identity=29.4871794871795, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74398; Mature: 74267

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHCCC
>Mature Secondary Structure 
ALTKNLSLTQTLGAVFLCITILMISLSVTSLRGIERVGAQFNQLSEQALPFALNNAALT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QNFLEQVKYLGYGTRSQSEQELNQVLNEWQKLDAQAGDEITRLQQNVQLLSSAEAVQQAE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QLQREILHFQQLAQSILKLQQLQLSKTAQISEQAKQFRYGLSSIGPEMGRIASFLAVDNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
EAMDAANRFTASASAMESAFLLLFIEEEMSAAQKYRQELKNRVAGLELAFDDFKEWYPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDYASLTAPYEMVLAGFQAQAVIEQIINKLEDAQQQNKDFASAAEVAQQLVTQLNQWSTL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AQQHIVQGKQEVTSTISAVTLTQQISGTLLVLAILAVWFGLRRWIGRALNNITRHLAQLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHKLNHRLDLVGPQDFQNVAAQLNQVIVSTHESLALVTRNCETLYQTAELSHGSAEQSNQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SLAAQNQALLTMAATINQLDASIREIAGVSHDSYTDSVEAAEHSAQGVKVIEQNQQRLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
LETTLAVNDAAMSELNQRVTSIREMVDMISGIADSTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEHH
ADEVRKLASDTSKQTTNIRDMMNELVTAASKSRQAVDESRKEMVTALQSSEEVKSTFMQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAVAHIRTRVEQITQATEEQKRATADVNKAVAQISEQGQETKRQLDAMLESAEQVAEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHQQAMLHKYELN
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]