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The map label for this gene is nadA

Identifier: 147674242

GI number: 147674242

Start: 1527658

End: 1528719

Strand: Reverse

Name: nadA

Synonym: VC0395_A1426

Alternate gene names: 147674242

Gene position: 1528719-1527658 (Counterclockwise)

Preceding gene: 147673656

Following gene: 147674034

Centisome position: 50.55

GC content: 46.7

Gene sequence:

>1062_bases
ATGAGCCACATACTCGATACTATAAATACAGTTTATCCCTTTCCCCCAAAACCTATCCCTCTTAGGGATGAGGAAAAGCA
AGCTTATATCGCTGAGATCAAACAACTCTTAATTGAGAAAGATGCGGTGTTGATTGCTCATTACTATACGGATCCTGAAA
TTCAAGCGCTTGCTGAATCGACAGGTGGGTTTGTGGGTGACTCGCTAGAGATGGCAAAATTTGGCAACCGCTATCCAGCC
ACAACCTTAATTATTGCGGGCGTACGTTTCATGGGAGAGTCAGCAAAGATTTTGACCCCAGAAAAACGCATCTTAATGCC
GACGCTCGAAGCGGAGTGCTCCCTCGATCTTGGTTGCCCAGCAGACAAGTTCACTGAGTTTTGCGATGCACACCCTGATC
ATACGGTAGTCGTGTATGCCAATACGTCAGCGGCGGTGAAAGCGCGTGCCGACTGGGTAGTGACATCAAGCATTGCTCTG
GAAATTGTTGAGCACTTAGATTCTGAGGGTAAACCTATTATTTGGGGTCCAGATCGACACTTAGGTGCTTATATTGCTAA
GAAAACGGGCGCAGACATGCTGTTATGGCAGGGCGAATGTGTCGTGCATGATGAGTTTTCTGCTGATGCTCTGCGTAAGA
TGAAGGCACTTTATCCTGATGCTGCGATTTTGGTTCATCCTGAATCGCCTGCGAGTGTTGTTGAATTGGCGGATGCGGTA
GGCTCAACAAGCCAACTCATTAAAGCGGCTAAGACATTACCACAGCAGAAAATGATTGTTGCTACGGATAAAGGAATTTT
CTTTAAAATGCAGCAAATGGTTCCCGAGAAGGAGCTGATTGAAGCTCCAACCGCAGGTGCGGGAGCGACTTGCCGTAGTT
GTGCGCATTGTCCTTGGATGGCGATGAATGGCCTTCAGGCTATTGCACAAGCACTGCGTGAAGGTGGCAAACAGCATGAA
ATTTTTGTGGATGAAGCGCTGAGAGTGAAATCACTTATCCCGCTTAATCGTATGTTGGATTTCGCTGAACAACTGAATTT
AAAAGTGAAAGGCAACGCGTAA

Upstream 100 bases:

>100_bases
ACACATTATTTCTCCCTCCTTGTTTAGGGCATTCAATTTTGCTTGCTGCTGGCTAGGGTGTACAATGCGCCGTCTATGGA
AGTTGTGTAGAGCAAGAGCA

Downstream 100 bases:

>100_bases
GTAAGCTGTCTGTTGTGCTGAAAATAGACATGCCCATCGAAAAAAAAACGGGCATGTCTAGCAAACATGATGGCTACTGA
GCTTCAGCTAACGTGACACC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAESTGGFVGDSLEMAKFGNRYPA
TTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEGKPIIWGPDRHLGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAV
GSTSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLQAIAQALREGGKQHE
IFVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA

Sequences:

>Translated_353_residues
MSHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAESTGGFVGDSLEMAKFGNRYPA
TTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEGKPIIWGPDRHLGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAV
GSTSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLQAIAQALREGGKQHE
IFVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA
>Mature_352_residues
SHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAESTGGFVGDSLEMAKFGNRYPAT
TLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALE
IVEHLDSEGKPIIWGPDRHLGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAVG
STSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLQAIAQALREGGKQHEI
FVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=70.2312138728324, Blast_Score=532, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_VIBC3 (A5F769)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F769
- SMR:   A5F769
- STRING:   A5F769
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1426
- eggNOG:   COG0379
- HOGENOM:   HBG291157
- OMA:   IAHPECE
- ProtClustDB:   PRK09375
- BioCyc:   VCHO345073:VC0395_A1426-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00567
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 38609; Mature: 38478

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: BINDING 47-47 BINDING 68-68 BINDING 139-139 BINDING 156-156 BINDING 226-226 BINDING 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAES
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRYPATTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCP
CCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKPIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCCH
LGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAV
HHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLQAIAQALREGGKQHEIFVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAES
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRYPATTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCP
CCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKPIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCCH
LGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAV
HHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLQAIAQALREGGKQHEIFVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA