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The map label for this gene is dadA

Identifier: 147674088

GI number: 147674088

Start: 333080

End: 334345

Strand: Reverse

Name: dadA

Synonym: VC0395_A0313

Alternate gene names: 147674088

Gene position: 334345-333080 (Counterclockwise)

Preceding gene: 147675694

Following gene: 147673424

Centisome position: 11.06

GC content: 51.11

Gene sequence:

>1266_bases
ATGATGGAAGTTTTGGTTTTAGGCAGTGGTGTGGTCGGATTAACCAGCGCTTGGTATCTTGCGCAGGCAGGCCATGATGT
CACCGTCGTCGATCGCCAACCACGTGGCGCCGAAGAAACCAGCTTTGCGAACGCAGGGCAAATCTCCTATGGCTACTCTT
CCCCTTGGGCTGCGCCGGGCATTCCGCAAAAAGCGCTAAAATGGATGCTGGAAAAACATGCACCACTCAAAATCCAACCC
TCGCTTGATCCTGCATTACTGAGCTGGATGGGCAAAATGCTGCTCAACTGCCAGTTGTCGCGCTACCAAGTTAACAAATC
GCGGATGTTGGCGATTGCCAACTATAGCCGCGAGTGTTTAAAAGCGCTCAATCAAACCTATTCGCTCGATTACCAAGGCC
GCCAACGCGGTACTTTGCAGGTATTTCGTGATGAAAAGCAGTTAACCGCGATTGAAAAAGACATGCAGCTTCTGGCGCAA
AGTGGCGTACGTTTTGAGTTACTGAATGTCGCCCAGTGTCTGACTCATGAACCGGGGCTCGCCCCTGTGCAGGAAAAACT
GGTGGGCGGCCTATGGCTGCCGGATGACGAAACGGGCGATTATTACTTGTTTTGCCAACAGTTAACCGAACTGGCCAAGC
AACAGGGTGTACGTTTTCATTTTGACTGCCACATTCAGCAACTGGTTTGTGAGGGCAAAAAGATCATCGGTGTCCAAACC
GATTTAGGCTTGCTCAAAGCGGATGCTTATGTAGTCGCATTGGGCAGTTATTCGACCTCATTGCTTAAACCGCTGGGGAT
TGAAATTCCTGTCTACCCAGTAAAAGGATACTCGTTAACCTTACCGATTATTGATGAAAAATTTGCGCCGCAATCGACCG
TGATGGATGAAACCTATAAGGTTGCACTGACTCGCTTTTCCGATCGGATCCGCGTGGCGGGAACGGCTGAGTTAGCGGGT
TTTGATCCAGCGATTCCAGAAGCACGTAAAGCGACGATTGAGATGGTCGCGCGTGATTTGTTTCCGCACGGCGGCGATTT
TGCAAAAGGGCAATTCTGGACCGGTTTTCGTCCCATGACTCCCGATGGCACACCAATCATCGGTGCCACTCCCTATACCA
ATCTCTATACAAATACTGGGCATGGCACACTGGGATGGACCATGGCTTGCGGATCCGCCAGTATTCTGGCCGATGTGCTC
ACCCATGGCGAAAGCCCGCTCAGCCGTTTGGGGCTAGATCTGTTCCGTTATCCGAAAGCATCTTAA

Upstream 100 bases:

>100_bases
GGACTTGCTTTTAGTTTTACTAAAGGGTGGTGATAATTTTTATCGATTGTTAATGAAAAGTAAACCTCCGAAACTGAGCC
GAAAATGAAGCAAGGAGTCA

Downstream 100 bases:

>100_bases
ATGCGCGGCTTTTTGGCTCTGCCTGCAGGAGCATGGCAGAGTCATCTCTCACAATCCGCACGCCATCCGCACGCCATCCG
CAGTGTAAAACTCCAATAAG

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS

Sequences:

>Translated_421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS
>Mature_421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787438, Length=419, Percent_Identity=53.9379474940334, Blast_Score=477, Evalue=1e-136,
Organism=Drosophila melanogaster, GI28571104, Length=328, Percent_Identity=26.219512195122, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA_VIBC3 (A5F3D0)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F3D0
- STRING:   A5F3D0
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0313
- eggNOG:   COG0665
- HOGENOM:   HBG729204
- OMA:   PITDESQ
- ProtClustDB:   PRK00711
- BioCyc:   VCHO345073:VC0395_A0313-MONOMER
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 46328; Mature: 46328

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
IPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECL
CCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCHHHEECCCHHEEEEHHHHHHHH
KALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGL
HHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
APVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
CHHHHHHHCCEECCCCCCCCEEEHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEEEEC
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYK
CCCCEECCEEEEEECCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHH
VALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMT
HHHHHHCCCEEEEEEHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
PDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKA
CCCCEEECCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHCHHHHCCCCC
S
C
>Mature Secondary Structure
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
IPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECL
CCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCHHHEECCCHHEEEEHHHHHHHH
KALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGL
HHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
APVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
CHHHHHHHCCEECCCCCCCCEEEHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEEEEC
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYK
CCCCEECCEEEEEECCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHH
VALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMT
HHHHHHCCCEEEEEEHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
PDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKA
CCCCEEECCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHCHHHHCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA