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The map label for this gene is atoS [H]

Identifier: 147673721

GI number: 147673721

Start: 640715

End: 642034

Strand: Direct

Name: atoS [H]

Synonym: VC0395_A0603

Alternate gene names: 147673721

Gene position: 640715-642034 (Clockwise)

Preceding gene: 147673821

Following gene: 147675202

Centisome position: 21.19

GC content: 45.0

Gene sequence:

>1320_bases
ATGGCAAAGAGTCGTTTATTGCTCTCTGAACTACTGGATCAACTCTCTTTTGCGCTCTGTATCGTGCGTAATGACTATGT
GATCGTCAAAGTGAATGAATATTTTGAATCACGTGTCATTTTTGATGGGGAAACCATGCAAGGGAAGAACATCCTAGAGC
TATTTCCTGAATCCGCCGATTATTTAAAGCGCAAAATTGATACGGCGCTGGTGATTGAATCCTCCAGTTTCAGCAGTTGG
GAGCAGAAACCGCATCTTTTGCCTTTCAAAAGTTCTCGCCCAGTGTCGGGCGAAGAAGAGCAGATGTATCAAAACCTCGA
AGTGATCCCGATCCACAGTGAAGATGGGACGATAGAGCATGTCTGTCTCTGTGTGTATGACGTCACGATTCAAGCGAGCC
AGCAACAGGAACTTAAGCGAGTATCGCAAAAGCTTGAAGAAGAGCATCAATCCCAAAAAGTGTTAATCAAGAAACTGGAA
GATGCACAAGGGCAATTAATTCAATCGGAAAAAATGGCCTCAATTGGTCAACTTTCTGCGGGGATCGCCCATGAAATTAA
TAACCCAGTAGGCTTTATTACCTCGAACCTACAAACGTTAAGCGACTACTTTAATAGCTTAGAGAAAGTTCTGAAAAGCA
TTACCCAGACGATTGGTCAGAGTAAAGACACGGCACTCAATGAAGCTTGTCAGAAGATCCTTAAACAAGGACAAGTAGAT
TTTATTTTGGAAGACACGGCGGAGTTGATTACCGAATCTCTCGAAGGCTCTTCACGCGTCATGTCGATTGTAAAAAACCT
CAAAGAGTTCTCACACGTTGACCGTTCAGAGTGGAGTTACGCCAATCTAGAAAACTGTATCGAATCGACGTTGAAAATCA
TCAATAACGAGATCAAGTACAACATCACGTTGGAGAAACACTACGCGGCCAATGTGCCCGATGTTTTTTGCCAGCCGATG
CAGATCAATCAGGTGTTACTCAACATATTGGTGAATGCCAGCCATGCCATCAAAGGCGAAGGGACGATCACCATTACCTT
ACAATCTGCGGGGGACGACTTTGTTGAAATACACATTCGAGACACGGGATGCGGTATTCCGGAGGAGATCCGCGAGCGTA
TTTTTGAACCCTTCTTTACCACAAAACCTGTCGGTTCGGGGACCGGATTAGGTTTATCTGTCTCCTACGGCATTATCAAT
AAGCACAATGGTACGATCAGCGTCACCAGCGAAGTCGGTAAGGGGAGCGAATTCACCATTCGTTTACCGGTGAATCCCAG
TGCCGAAGCGGTAGACAATACCGATGCCAAAGCGATGTAA

Upstream 100 bases:

>100_bases
AAGGCCTCTTTTTCTGCCAAAACCATCATCTGTTTTGCTGATAAAGAGTTAGATAAGGTATTTGCCCATCTCGACGAACT
CTTGATGTAAGGATACGAGT

Downstream 100 bases:

>100_bases
ATGGGGGCATTATGGTAGACAAACTACGCACTTCTGGCGCAGCTATGCGAGAACAAGAGAATGATTGCCATATTCCTTTT
GCTCTGTTGGCCTTTATCAA

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAKSRLLLSELLDQLSFALCIVRNDYVIVKVNEYFESRVIFDGETMQGKNILELFPESADYLKRKIDTALVIESSSFSSW
EQKPHLLPFKSSRPVSGEEEQMYQNLEVIPIHSEDGTIEHVCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLE
DAQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNEACQKILKQGQVD
FILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKYNITLEKHYAANVPDVFCQPM
QINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIRDTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIIN
KHNGTISVTSEVGKGSEFTIRLPVNPSAEAVDNTDAKAM

Sequences:

>Translated_439_residues
MAKSRLLLSELLDQLSFALCIVRNDYVIVKVNEYFESRVIFDGETMQGKNILELFPESADYLKRKIDTALVIESSSFSSW
EQKPHLLPFKSSRPVSGEEEQMYQNLEVIPIHSEDGTIEHVCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLE
DAQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNEACQKILKQGQVD
FILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKYNITLEKHYAANVPDVFCQPM
QINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIRDTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIIN
KHNGTISVTSEVGKGSEFTIRLPVNPSAEAVDNTDAKAM
>Mature_438_residues
AKSRLLLSELLDQLSFALCIVRNDYVIVKVNEYFESRVIFDGETMQGKNILELFPESADYLKRKIDTALVIESSSFSSWE
QKPHLLPFKSSRPVSGEEEQMYQNLEVIPIHSEDGTIEHVCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLED
AQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNEACQKILKQGQVDF
ILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKYNITLEKHYAANVPDVFCQPMQ
INQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIRDTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIINK
HNGTISVTSEVGKGSEFTIRLPVNPSAEAVDNTDAKAM

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=268, Percent_Identity=31.7164179104478, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=31.6981132075472, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=337, Percent_Identity=27.893175074184, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790300, Length=273, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=28.8461538461538, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=162, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=328, Percent_Identity=25.9146341463415, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786783, Length=115, Percent_Identity=32.1739130434783, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48950; Mature: 48819

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSRLLLSELLDQLSFALCIVRNDYVIVKVNEYFESRVIFDGETMQGKNILELFPESAD
CCCHHHHHHHHHHHHHHEEEEEECCEEEEEEECHHCCEEEECCCCCCCCCHHHHCCCHHH
YLKRKIDTALVIESSSFSSWEQKPHLLPFKSSRPVSGEEEQMYQNLEVIPIHSEDGTIEH
HHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCHHH
VCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLEDAQGQLIQSEKMASIGQLSA
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNEACQKILKQGQVD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEE
FILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKY
EEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
NITLEKHYAANVPDVFCQPMQINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIR
EEEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCEEEEEEE
DTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIINKHNGTISVTSEVGKGSEFTI
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEE
RLPVNPSAEAVDNTDAKAM
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKSRLLLSELLDQLSFALCIVRNDYVIVKVNEYFESRVIFDGETMQGKNILELFPESAD
CCHHHHHHHHHHHHHHEEEEEECCEEEEEEECHHCCEEEECCCCCCCCCHHHHCCCHHH
YLKRKIDTALVIESSSFSSWEQKPHLLPFKSSRPVSGEEEQMYQNLEVIPIHSEDGTIEH
HHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCHHH
VCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLEDAQGQLIQSEKMASIGQLSA
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNEACQKILKQGQVD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEE
FILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKY
EEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
NITLEKHYAANVPDVFCQPMQINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIR
EEEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCEEEEEEE
DTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIINKHNGTISVTSEVGKGSEFTI
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEE
RLPVNPSAEAVDNTDAKAM
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]