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The map label for this gene is menC [H]

Identifier: 147673492

GI number: 147673492

Start: 1676354

End: 1677352

Strand: Reverse

Name: menC [H]

Synonym: VC0395_A1558

Alternate gene names: 147673492

Gene position: 1677352-1676354 (Counterclockwise)

Preceding gene: 147674367

Following gene: 147675543

Centisome position: 55.47

GC content: 52.25

Gene sequence:

>999_bases
ATGCGTCATGCAACCCTCTATCGCTACCAACTGCCGATGGATAGCGGTGTCATCCTTCGCAATGAGAAACTGACTCAGCG
TGAAGGCTTTATTGTCGAACTGACCGAAAACGGCCGTACTGCACGCGGCGAGATTGCTCCACTGCCCGGCTTTAGCCGCG
AAACGCTGGAAGAAGCGGGCGTACAAGCACAAGCGCTGCTTGAGCTTTGGGTCAATAGTCAGGTTATCGATTGGGATGCA
CAGCATCCTTCGGTGGCTTTTGGTATTTCGATGGCGCACTACGAGCTAGAACAAGCGTTGCCCGCGCAAGGCAACTACTA
TGTTGCGCCGCTGTGTACGGGCGATCCTGATGAGCTGCTGCCGGTGTTGAACAACTTACCGGGGCAGAAAGTCGCTAAAG
TTAAAGTTGGACTGTATGAACCGATCCGTGATGGCATGCTCGTCAATCTGTTCTTGGAATCGATGCCGGATTTAACGCTG
CGTTTGGATGCCAACCGCGCGTGGACTCCTGCCAAAGCGCTCAAGTTTGCTCAATACGTCGCGCCGTCTTTACGCAGCCG
TATCGCCTTTCTGGAAGAGCCGTGCCAGTCGCCAAGCGAAAGCATCGCATTTTCGATTGATACAGGGATTGCGATTGCGT
GGGACGAAACCTTACAAGAAGCGGTTCGCGATGCGGATTTTGCTTTAGAGAATCTGTTAGGTGTCAAAACCATTGTCATC
AAACCAACCCTAATTGGCTCGGTGTATCGTGTAGAGGCTTTGATCGAGAAAGCCAAAGCACTTGGGCTACAAGCTGTGAT
CAGCTCTAGCTTAGAGTCGAGCTTGGGCTTGAACCAGTTAGCACGTTTAGCGCATAAACTGCTGCCTAATGAAGTACCGG
GACTGGATACGATGGGATTATTCCGAACTCAGCTCGAAACGCCTTGGCCAAATAGCTCACTGCCTGTGGTTGCCCTGCAA
GAGCAGTCAATCGTATGGCGCTCGGAATCTTCCCTGTGA

Upstream 100 bases:

>100_bases
GCGTAACCCATAATTCTTCTCAGAGCGGCGTCCTGCCGCTCTTTCTCTTTGAGCATAAACCCCGTTTATGTGGATGTATT
GGATATAGGAAGAGATCAGC

Downstream 100 bases:

>100_bases
GCCTTTGGCAGCCTTGGCTTGAGCGTGACCCCAAGCAGGTTGCGCTGAGTCATGCTGGGCAAACCCTGACTTGGCAAGTA
TTAGATAGCCAAGTAGCGCA

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRHATLYRYQLPMDSGVILRNEKLTQREGFIVELTENGRTARGEIAPLPGFSRETLEEAGVQAQALLELWVNSQVIDWDA
QHPSVAFGISMAHYELEQALPAQGNYYVAPLCTGDPDELLPVLNNLPGQKVAKVKVGLYEPIRDGMLVNLFLESMPDLTL
RLDANRAWTPAKALKFAQYVAPSLRSRIAFLEEPCQSPSESIAFSIDTGIAIAWDETLQEAVRDADFALENLLGVKTIVI
KPTLIGSVYRVEALIEKAKALGLQAVISSSLESSLGLNQLARLAHKLLPNEVPGLDTMGLFRTQLETPWPNSSLPVVALQ
EQSIVWRSESSL

Sequences:

>Translated_332_residues
MRHATLYRYQLPMDSGVILRNEKLTQREGFIVELTENGRTARGEIAPLPGFSRETLEEAGVQAQALLELWVNSQVIDWDA
QHPSVAFGISMAHYELEQALPAQGNYYVAPLCTGDPDELLPVLNNLPGQKVAKVKVGLYEPIRDGMLVNLFLESMPDLTL
RLDANRAWTPAKALKFAQYVAPSLRSRIAFLEEPCQSPSESIAFSIDTGIAIAWDETLQEAVRDADFALENLLGVKTIVI
KPTLIGSVYRVEALIEKAKALGLQAVISSSLESSLGLNQLARLAHKLLPNEVPGLDTMGLFRTQLETPWPNSSLPVVALQ
EQSIVWRSESSL
>Mature_332_residues
MRHATLYRYQLPMDSGVILRNEKLTQREGFIVELTENGRTARGEIAPLPGFSRETLEEAGVQAQALLELWVNSQVIDWDA
QHPSVAFGISMAHYELEQALPAQGNYYVAPLCTGDPDELLPVLNNLPGQKVAKVKVGLYEPIRDGMLVNLFLESMPDLTL
RLDANRAWTPAKALKFAQYVAPSLRSRIAFLEEPCQSPSESIAFSIDTGIAIAWDETLQEAVRDADFALENLLGVKTIVI
KPTLIGSVYRVEALIEKAKALGLQAVISSSLESSLGLNQLARLAHKLLPNEVPGLDTMGLFRTQLETPWPNSSLPVVALQ
EQSIVWRSESSL

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=323, Percent_Identity=56.9659442724458, Blast_Score=351, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36613; Mature: 36613

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHATLYRYQLPMDSGVILRNEKLTQREGFIVELTENGRTARGEIAPLPGFSRETLEEAG
CCCCEEEEEECCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHC
VQAQALLELWVNSQVIDWDAQHPSVAFGISMAHYELEQALPAQGNYYVAPLCTGDPDELL
CHHHHHHHHHHCCEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHH
PVLNNLPGQKVAKVKVGLYEPIRDGMLVNLFLESMPDLTLRLDANRAWTPAKALKFAQYV
HHHHCCCCCEEEEEEECCHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
APSLRSRIAFLEEPCQSPSESIAFSIDTGIAIAWDETLQEAVRDADFALENLLGVKTIVI
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEE
KPTLIGSVYRVEALIEKAKALGLQAVISSSLESSLGLNQLARLAHKLLPNEVPGLDTMGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHH
FRTQLETPWPNSSLPVVALQEQSIVWRSESSL
HHHHCCCCCCCCCCCEEEEECCEEEECCCCCC
>Mature Secondary Structure
MRHATLYRYQLPMDSGVILRNEKLTQREGFIVELTENGRTARGEIAPLPGFSRETLEEAG
CCCCEEEEEECCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHC
VQAQALLELWVNSQVIDWDAQHPSVAFGISMAHYELEQALPAQGNYYVAPLCTGDPDELL
CHHHHHHHHHHCCEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHH
PVLNNLPGQKVAKVKVGLYEPIRDGMLVNLFLESMPDLTLRLDANRAWTPAKALKFAQYV
HHHHCCCCCEEEEEEECCHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
APSLRSRIAFLEEPCQSPSESIAFSIDTGIAIAWDETLQEAVRDADFALENLLGVKTIVI
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEE
KPTLIGSVYRVEALIEKAKALGLQAVISSSLESSLGLNQLARLAHKLLPNEVPGLDTMGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHH
FRTQLETPWPNSSLPVVALQEQSIVWRSESSL
HHHHCCCCCCCCCCCEEEEECCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]