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The map label for this gene is tcpS [H]

Identifier: 147673398

GI number: 147673398

Start: 386447

End: 386905

Strand: Direct

Name: tcpS [H]

Synonym: VC0395_A0359

Alternate gene names: 147673398

Gene position: 386447-386905 (Clockwise)

Preceding gene: 147674167

Following gene: 147673300

Centisome position: 12.78

GC content: 30.94

Gene sequence:

>459_bases
ATGAATATCAAACTATCATTTATTTCAATTGCTTTTCTATCGTTAAGTTTTAATGTTGCTGCTAACGAATTTGAAAAATC
TCAAGAGCACTACAAAAGTGTAACTGATTTAAAAAACAAAATCGAAATACTAGAGTTAGAAAAGAAAATAACAGAGCTGA
GTGGCGAGATTCGCAATGCAAGAATGCCAAAAATAGATAAGTCTGCACCCGTTTTATCTCCTCAGCCTGTAGTAAAATCG
TCAGAAGAATTACAAAAAAGTATCGAACATATAGAAGAAGAGCTCAAAGTGGAATTGGCTTATTTGGTTAACAATGGTCA
ACAAAAAAAATATACATTCAATCTTAATGGCAAACTTATCACATTGGTTAATGGTGATTTTGTAAATGGTTGGAAATTCA
TTGAAGACCAAAATAAAATTCAATTTTTCAAGGGCAATAAGGTAATCGATGTCAATTGA

Upstream 100 bases:

>100_bases
TATTATGAATAATAGTATGATGATTACGTCTATCTCTTTGCAAAATTCAAGTTTTAAATCCAAGTTAAATTATTACTGCT
ATTAAGGTGGGATTAGAGAA

Downstream 100 bases:

>100_bases
TATAAAGTATTTAAGTCGTATTGATATAGATCGTGAGGAGTTTTTCTTTAAAGACTCGAGATTAATGTGTAAGAAATTCG
ATGAAGAGCGTGAGGTATTA

Product: toxin co-regulated pilus biosynthesis protein S

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpS [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFFKGNKVIDVN

Sequences:

>Translated_152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFFKGNKVIDVN
>Mature_152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFFKGNKVIDVN

Specific function: The toxin coregulated pilus (TCP) is essential for successful colonization of the small intestine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm. Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020213
- ProDom:   PD091271 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17417; Mature: 17417

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNA
CCEEEHHHHHEEHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RMPKIDKSAPVLSPQPVVKSSEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEECCCCCEEEEEECCCEEE
TLVNGDFVNGWKFIEDQNKIQFFKGNKVIDVN
EEEECCCCCCEEEECCCCEEEEEECCEEEECC
>Mature Secondary Structure
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNA
CCEEEHHHHHEEHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RMPKIDKSAPVLSPQPVVKSSEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEECCCCCEEEEEECCCEEE
TLVNGDFVNGWKFIEDQNKIQFFKGNKVIDVN
EEEECCCCCCEEEECCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8097178; 10952301 [H]