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The map label for this gene is rarA [H]

Identifier: 147673167

GI number: 147673167

Start: 668414

End: 669763

Strand: Direct

Name: rarA [H]

Synonym: VC0395_A0627

Alternate gene names: 147673167

Gene position: 668414-669763 (Clockwise)

Preceding gene: 147675332

Following gene: 147674801

Centisome position: 22.1

GC content: 52.15

Gene sequence:

>1350_bases
GTGAGTAATTACAGCTTAGATTTTTCCGGCGACGAAGATTTTCGTCCGTTAGCTGCCCGTATGCGTCCACAAACGGTGGA
GCAGTATATTGGTCAGCAACACATCTTAGGGCCGGGAAAACCGCTGCGCCGTGCATTAGAAGCGGGGCATATTCACTCGA
TGATTCTTTGGGGACCTCCGGGCACCGGAAAAACCACTTTAGCCGAAGTGGCAGCCAACTACGCCAATGCGGAAGTGGAA
CGCGTATCGGCAGTGACGTCCGGAGTCAAAGAGATCCGTGCCGCGATCGAAAAAGCGCGTGAGAACAAACTCAGTGGTCG
ACGCACTATTTTGTTTGTCGACGAAGTCCATCGCTTTAATAAATCGCAGCAAGATGCGTTTTTGCCGCATATTGAAGACG
GTACGGTCACTTTTATTGGCGCAACCACGGAAAACCCTTCTTTTGAGCTTAATAACGCGCTGCTTTCCCGCGCGCGGGTT
TATAAGCTCACCTCACTCAATCAACAAGAAATTCTGCAAGCTCTGCATCAAGCGATTGCCGATACTGAATGCGGGCTTGG
CAAAGTGGCGGCGGTATTTGCTGATAATGTTTTAGATCGCCTAGCCGAACTGGTCAATGGCGATGCGCGCATGTCGCTCA
ATTATCTTGAGCTGCTGTACGACATGGCTCGCGAAGATGATCAGGGACGCAAGCAGATTGATCTGCCTTTATTGGCTGAG
GTCGCTGGTGAAAAAGTGTCGCGCTTTGATAACAAGGGCGATATTTGGTATGACCTGATTTCCGCTGTACACAAGTCGAT
TCGAGGTTCTGATCCCGATGCGGCTCTGTATTGGGCGGCGCGGATGATTTCCGCAGGCTGTGACCCTTTGTATATCGCGC
GCCGTCTGCTCGCGATTGCCTCTGAAGATGTTGGTAATGCCGACCCGCGGGGCATGCAAGTGGCGCTTTCTGCATGGGAT
TGCTTTACCCGCGTGGGGCCTGCAGAAGGCGAGCGCGCGATTGCTCAAGCGATTGTCTACCTCGCCTGCGCACCGAAAAG
CAATGCGGTGTACACCGCGTGGAAACAAGCGCTGTCGGATGCGCATAATCTGCCTGAGTTTGAAGTACCGCCGCATCTGC
GTAATGCCCCAACGCGATTGATGAAAGATCTCGGTTATGGTGAGGAATACCGTTACGCCCATGATGAACCGGGCGCTTAT
GCTGCAGGGGAGTGCTATTTCCCACCAGAAATGAGTGGAACTCGCTACTATCAGCCTACTCAACGCGGGCTAGAAACTAA
GATTGCTGAAAAGTTAGCGTATCTGGCGGATTTGAACGCAAAAAGCCCACAAAAGCGCTATGAAAAGTAG

Upstream 100 bases:

>100_bases
ACAGCAGAAACCAAACGCTAGCGTATTTAACTACAAAGTGCCGAAAGGCGTGGAAGTTGACGATCAGCGTAACTAAATCA
GCACCAAGGAAGCGAGTCGA

Downstream 100 bases:

>100_bases
TGCCTTTTGGTTATCTTTGGCAGGGTAAATTTCAATACGCGTGGCTTTGGCTAAAAAGGAAGCACACGCGCTTTCTCGCA
ACTCTTAAAGCATAGGATTA

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNQQEILQALHQAIADTECGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALSAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAY
AAGECYFPPEMSGTRYYQPTQRGLETKIAEKLAYLADLNAKSPQKRYEK

Sequences:

>Translated_449_residues
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNQQEILQALHQAIADTECGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALSAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAY
AAGECYFPPEMSGTRYYQPTQRGLETKIAEKLAYLADLNAKSPQKRYEK
>Mature_448_residues
SNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVER
VSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVY
KLTSLNQQEILQALHQAIADTECGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAEV
AGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALSAWDC
FTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYA
AGECYFPPEMSGTRYYQPTQRGLETKIAEKLAYLADLNAKSPQKRYEK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=441, Percent_Identity=41.9501133786848, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI18426904, Length=441, Percent_Identity=37.6417233560091, Blast_Score=251, Evalue=8e-67,
Organism=Escherichia coli, GI1787119, Length=447, Percent_Identity=73.1543624161074, Blast_Score=674, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324111, Length=426, Percent_Identity=40.8450704225352, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6324039, Length=210, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 49778; Mature: 49647

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNQQEILQALHQAIA
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DTECGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SEDVGNADPRGMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYAAGECYFPPEMSGTRYYQPT
HHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHH
QRGLETKIAEKLAYLADLNAKSPQKRYEK
HHHHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure 
SNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNQQEILQALHQAIA
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DTECGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SEDVGNADPRGMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYAAGECYFPPEMSGTRYYQPT
HHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHH
QRGLETKIAEKLAYLADLNAKSPQKRYEK
HHHHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]