Click here to switch to the map view.

The map label for this gene is ftsY [H]

Identifier: 147673157

GI number: 147673157

Start: 2531160

End: 2532323

Strand: Reverse

Name: ftsY [H]

Synonym: VC0395_A2374

Alternate gene names: 147673157

Gene position: 2532323-2531160 (Counterclockwise)

Preceding gene: 147675359

Following gene: 147675112

Centisome position: 83.74

GC content: 49.83

Gene sequence:

>1164_bases
ATGACGGAAAAAAAGAAGCGTGGCTTGTTGTCATGGCTTGGATTTGGTGACGAAGAGAAAAGCCAAACCACTGCAACGGA
TACTCAAACGCAGGATGAACCACAAAGCCAAGCCGATGTTGAAGCGGTGGCGATTCAAACGGAAACTGCGTTAACAGAAA
CAGAAACAGAAACAGAAACAGAAACAGAAACAGAAACAGCCACGGTTGAACCTGCACGTATTGTTGAACAAGAGAAACCG
ACCGAAAGTTTCTTTGCGCGCTTAAAGCGCAGTTTGAGCCGCACCAAAGCGAATATTGGCGCTGGCTTCTTTGGCCTGTT
TAAAGGCAAAAAGATTGATGATGACCTGTTCGAAGAGCTCGAAGAACAACTGCTGATTGCCGATGTCGGCATGGATACGA
CCAGCAAAATCATCGCTAATTTGACCGCCAGAGCTTCTCGCCAGCAACTGCGTGATGGGGAAGCGCTGTACGGTCTGCTG
AAAGAAGAGATGGCCGAGATTCTCTCTCAGGTCGAGCAGCCATTGGTGATCGACACTGAGAAAAAACCTTACGTGATCTT
GATGGTGGGCGTGAATGGGGTGGGTAAAACTACCACGATCGGTAAACTGGCTAAACAGTTCCAAGCGCAAGGCAAGAAAG
TGATGTTGGCAGCGGGCGATACCTTCCGTGCTGCAGCGGTTGAGCAGTTGCAAGTGTGGGGAGAGCGCAATCAAGTGCCT
GTCATCGCTCAGCATACTGGCGCCGACAGTGCCTCCGTCATTTATGATGCGATTGAAGCGGCGAAAGCGCGCGGGATTGA
CGTGGTGATTGCGGATACCGCAGGCCGTCTGCAAAACAAAAGTAACCTGATGGAAGAGCTGCGCAAGATTGTGCGCGTGA
TGAAGAAGATTGATGACAGTGCGCCACATGAAATCATGTTGACGCTGGATGCGGGTACCGGACAAAACGCGATCAGTCAG
GCCAAATTGTTTAGTGATGTAGCGCCCATCACGGGCATTACCTTAACTAAGCTTGATGGCACCGCTAAAGGTGGCGTGAT
TTTCGCGATTGCCGATCAATTCCAGATCCCAATCCGTTATATCGGTGTCGGCGAGAAAATTGACGACTTACGTCCATTTG
CAACACAAGAGTTTATCGACGCGCTATTTAGCCGCGAAGAATAA

Upstream 100 bases:

>100_bases
AGCAAAAAGTTTTCACTGCTTTGTCATTTTTTCTTTTCGGGGCCGCAATAATGGCCAAGAAAAGTCTGTATTAAAATAAA
GCGATTCAGGATAGCTCCAG

Downstream 100 bases:

>100_bases
ACCAATCTCAGTTGGCACAGTGTGCCAGCCTTGTCAGGGGGAGACGGCGTGATCAGGTTTCAGCAAGTCAGTAAAGCGTA
TCGAGGTGGACGACAAGCGC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETATVEPARIVEQEKP
TESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLL
KEEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGERNQVP
VIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQ
AKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE

Sequences:

>Translated_387_residues
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETATVEPARIVEQEKP
TESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLL
KEEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGERNQVP
VIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQ
AKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE
>Mature_386_residues
TEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETATVEPARIVEQEKPT
ESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLK
EEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGERNQVPV
IAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQA
KLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=271, Percent_Identity=32.1033210332103, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI226371618, Length=205, Percent_Identity=37.0731707317073, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI295424842, Length=333, Percent_Identity=27.9279279279279, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI23308697, Length=333, Percent_Identity=27.9279279279279, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=33.5664335664336, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1789874, Length=313, Percent_Identity=78.2747603833866, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1788963, Length=298, Percent_Identity=32.2147651006711, Blast_Score=148, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=205, Percent_Identity=31.219512195122, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=320, Percent_Identity=30, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=212, Percent_Identity=35.8490566037736, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=31.1688311688312, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17647949, Length=280, Percent_Identity=33.5714285714286, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24641198, Length=408, Percent_Identity=27.2058823529412, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 42345; Mature: 42213

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETET
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCC
ETETETATVEPARIVEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEEL
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
EEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLKEEMAEILSQVEQPLVIDTE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEECC
KKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGERNQVP
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
VIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDS
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCC
APHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRY
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEE
IGVGEKIDDLRPFATQEFIDALFSREE
EECCCCHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETET
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCC
ETETETATVEPARIVEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEEL
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
EEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLKEEMAEILSQVEQPLVIDTE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEECC
KKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGERNQVP
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
VIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDS
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCC
APHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRY
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEE
IGVGEKIDDLRPFATQEFIDALFSREE
EECCCCHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]