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The map label for this gene is grxD [H]

Identifier: 147673099

GI number: 147673099

Start: 1755698

End: 1756030

Strand: Reverse

Name: grxD [H]

Synonym: VC0395_A1631

Alternate gene names: 147673099

Gene position: 1756030-1755698 (Counterclockwise)

Preceding gene: 147675696

Following gene: 147675446

Centisome position: 58.07

GC content: 48.05

Gene sequence:

>333_bases
ATGGAAACTATTGACAAAATCAAACAGCAAATCGCCGAGAACCCGATTCTGCTTTATATGAAAGGCTCACCGAAACTGCC
AAGCTGTGGTTTCTCTTCGCAAGCCGCACAAGCTCTGATGGCTTGTGGTGAGAAGTTTGCTTATGTAGATATCCTACAAA
ACCCAGACATCCGTGCAGAGTTGCCGGTTTACGCGCAGTGGCCAACGTTTCCACAACTGTGGATTGAAGGCGAGCTGATT
GGCGGTTGTGACATCATGCTGGAAATGTTCCAAAAGGGTGAACTGCAAACTCTGGTAAAAGAAGCGGCTGCTCGCTCAGC
AAGCCAAGAGTAA

Upstream 100 bases:

>100_bases
GCCAAGTCGAGCGTATATCCATATTGAGAATATGCTTTTTATTCTCGGTTATTCCTTTAGAATGTGCCCATATTTGATGA
CATCCATTAACGAGGAAGCG

Downstream 100 bases:

>100_bases
TACTGGTTAAATTTACAGTTTTCCTTGATTTCATAAGGCCACATTGAGTAATGTGGCCTTAATTTTATCTCGTCAGCGAT
TTCCATGACCCGGTTATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
METIDKIKQQIAENPILLYMKGSPKLPSCGFSSQAAQALMACGEKFAYVDILQNPDIRAELPVYAQWPTFPQLWIEGELI
GGCDIMLEMFQKGELQTLVKEAAARSASQE

Sequences:

>Translated_110_residues
METIDKIKQQIAENPILLYMKGSPKLPSCGFSSQAAQALMACGEKFAYVDILQNPDIRAELPVYAQWPTFPQLWIEGELI
GGCDIMLEMFQKGELQTLVKEAAARSASQE
>Mature_110_residues
METIDKIKQQIAENPILLYMKGSPKLPSCGFSSQAAQALMACGEKFAYVDILQNPDIRAELPVYAQWPTFPQLWIEGELI
GGCDIMLEMFQKGELQTLVKEAAARSASQE

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42516576, Length=98, Percent_Identity=36.734693877551, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI95113651, Length=97, Percent_Identity=40.2061855670103, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787943, Length=108, Percent_Identity=78.7037037037037, Blast_Score=189, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17556042, Length=102, Percent_Identity=30.3921568627451, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988153, Length=84, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988159, Length=75, Percent_Identity=42.6666666666667, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=107, Percent_Identity=39.2523364485981, Blast_Score=91, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320303, Length=87, Percent_Identity=40.2298850574713, Blast_Score=84, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321022, Length=74, Percent_Identity=47.2972972972973, Blast_Score=84, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24642023, Length=101, Percent_Identity=40.5940594059406, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921242, Length=96, Percent_Identity=36.4583333333333, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12223; Mature: 12223

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIDKIKQQIAENPILLYMKGSPKLPSCGFSSQAAQALMACGEKFAYVDILQNPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
LPVYAQWPTFPQLWIEGELIGGCDIMLEMFQKGELQTLVKEAAARSASQE
CCEEECCCCCCCEEECCCEECHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
METIDKIKQQIAENPILLYMKGSPKLPSCGFSSQAAQALMACGEKFAYVDILQNPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
LPVYAQWPTFPQLWIEGELIGGCDIMLEMFQKGELQTLVKEAAARSASQE
CCEEECCCCCCCEEECCCEECHHHHHHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]