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The map label for this gene is dtd

Identifier: 147673087

GI number: 147673087

Start: 2468624

End: 2469058

Strand: Reverse

Name: dtd

Synonym: VC0395_A2313

Alternate gene names: 147673087

Gene position: 2469058-2468624 (Counterclockwise)

Preceding gene: 147674039

Following gene: 147675114

Centisome position: 81.65

GC content: 51.03

Gene sequence:

>435_bases
GTGATAGCACTGATCCAACGAGTAAGTGAAGCCGCAGTACGGGTTGATGGTGAAGTGGTCGGCGCAATTGATAAGGGACT
TTTAGTGCTACTCGGTGTCGAACGTGAAGATGATGAAGCGAAAGCCAAGCGATTGGTTGAGCGAGTGACCAGCTATCGAG
TGTTTGAAGATAGCGAAGGTAAGATGAATCTGAGCGTGAAAGATGTGGGTGGCAGTGTGTTAGTGGTGTCGCAATTTACG
CTGCCAGCTGACACCAAAAAAGGGACTCGTGCTGGATTTTCGCGCGGCGCTGCCCCACAAGAGGCTGAGCGGTTATATGA
TTATTTCTCTGACCTGTGTGCCCAGATTTTGCCAACCGAGCGCGGCCGTTTTGCGGCGGATATGAAAGTGTCACTGATCA
ATGATGGGCCGGTGACGTTTTGGCTACAGGCTTAA

Upstream 100 bases:

>100_bases
CTGCTTTGGGCGAGCGTGAACACTGGAGTGACTCACAAGACATGCTACACTTTGCACCATTACCAAAGAATGAAAAAGAA
TGAAGTAGAGGAAAAACAGA

Downstream 100 bases:

>100_bases
TTTGCCTCGTGTTACCAAATGAATAACCAAGCGTGTCTTGCGTAAGGTAAGGCACCTGTTCAGGGATTGAGTATGTTTAA
ACTTATTACGCCGACCACGG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MIALIQRVSEAAVRVDGEVVGAIDKGLLVLLGVEREDDEAKAKRLVERVTSYRVFEDSEGKMNLSVKDVGGSVLVVSQFT
LPADTKKGTRAGFSRGAAPQEAERLYDYFSDLCAQILPTERGRFAADMKVSLINDGPVTFWLQA

Sequences:

>Translated_144_residues
MIALIQRVSEAAVRVDGEVVGAIDKGLLVLLGVEREDDEAKAKRLVERVTSYRVFEDSEGKMNLSVKDVGGSVLVVSQFT
LPADTKKGTRAGFSRGAAPQEAERLYDYFSDLCAQILPTERGRFAADMKVSLINDGPVTFWLQA
>Mature_144_residues
MIALIQRVSEAAVRVDGEVVGAIDKGLLVLLGVEREDDEAKAKRLVERVTSYRVFEDSEGKMNLSVKDVGGSVLVVSQFT
LPADTKKGTRAGFSRGAAPQEAERLYDYFSDLCAQILPTERGRFAADMKVSLINDGPVTFWLQA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=39.0728476821192, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=68.0555555555556, Blast_Score=201, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=42.6573426573427, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=39.1891891891892, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=38.0952380952381, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_VIBC3 (A5F4Q7)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F4Q7
- SMR:   A5F4Q7
- STRING:   A5F4Q7
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2313
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   VCHO345073:VC0395_A2313-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15737; Mature: 15737

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSEAAVRVDGEVVGAIDKGLLVLLGVEREDDEAKAKRLVERVTSYRVFEDSEG
CHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEECCCC
KMNLSVKDVGGSVLVVSQFTLPADTKKGTRAGFSRGAAPQEAERLYDYFSDLCAQILPTE
EEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RGRFAADMKVSLINDGPVTFWLQA
CCCEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSEAAVRVDGEVVGAIDKGLLVLLGVEREDDEAKAKRLVERVTSYRVFEDSEG
CHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEECCCC
KMNLSVKDVGGSVLVVSQFTLPADTKKGTRAGFSRGAAPQEAERLYDYFSDLCAQILPTE
EEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RGRFAADMKVSLINDGPVTFWLQA
CCCEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA