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The map label for this gene is yngJ [H]

Identifier: 146343640

GI number: 146343640

Start: 7146874

End: 7148043

Strand: Reverse

Name: yngJ [H]

Synonym: BRADO6880

Alternate gene names: 146343640

Gene position: 7148043-7146874 (Counterclockwise)

Preceding gene: 146343641

Following gene: 146343639

Centisome position: 95.86

GC content: 65.38

Gene sequence:

>1170_bases
ATGCTCTTCACCGCCGATCACGACGAACCGCGCCGCATCCTGCAGAAGTTCATCGCCGCCGAGATCAACCCCCATGTCGA
CGAATGGGAGGAGGCCGGCATCTTCCCCGCGCATGAGCTGTTCAAGAAGCTCGGTGACCTCGGCTTCCTCGGCCTCAACA
AGCCGGTCGAGTTCGGCGGCCAGGGACTGGACTATTCCTACGCGCTGATGATGGCGGAGGAGCTCGGCGCCATCAATTGC
GGCGCCATCCCGATGGCGATCGGGGTGCAGACCGACATGGCGACGCCGGCGCTGGCGCGGTTCGGCTCCGACACCGTGCG
CAAGGAGTTCCTGGCGCCTGCGATCTCCGGCGACTACGTCGCCTGCATCGGCGTCTCCGAGCCCGGTGCCGGCTCCGACG
TCGCCTCGATCAAGACCCAGGCGCGCGCCGATGGCGACGACTACGTCATCAATGGCGGCAAGATGTGGATCACCAACGGC
ACGCAGGCGGATTTCATCTGCCTGCTCGCCAACACCAGCGACGGCCCGGTTCACCGCAACAAGTCGCTGATCTGCGTGCC
GATGAAGAGCAGGGGCGTGCAGGTCGCGCGCAAGCTCGACAAGATGGGCATGCGCTCGTCCGACACCGCGCAGATCTTCT
TCGATAATGTGAGAGTGCCGAAGCGCAACCGCGTCGGCGAGGAGGGTATGGGCTTCACCTACCAGATGATGCAGTTCCAG
GAGGAGCGGCTGTGGGCCGGCGCGGCCTGCCTCAAGGCGCATGAGGCGATCATCAACGCGACCATCGAGTACACGCGAAA
TCGCAAGGCGTTCGGCCGCTCGATCCTCGACAACCAGGTCGTCCATTTCCGCCTCGCCGAGCTGCAGACCGAGGTCGAGC
TGCTGCGCGCGCTGACCTATCAGGCCGCCGAGGCGCTGGTGGCCGGCGAAGATGTGACGCGGCTCGCGACGATGGTGAAG
CTGAAGACGGGCCGGCTGGGCCGCGAGCTCACCGATGCCTGCCTGCAATATTGGGGCGGCATGGGCTTTATGAACGAGAC
GCCGGTCAGCCGCGCTTATCGTGATTCGCGCCTGAGCTCGATCGGCGGCGGCGCCGACGAGGTGATGCTGACGATCCTGT
GCAAGATGATGGGCACGTTGCCGGGCATGGCCAAGGCGGGGAACGCCTGA

Upstream 100 bases:

>100_bases
GACCCTCATGGTGAGGAGCGCCCCTTGGCGCGTCTCGAACCATGAGGCCGGATGGCTTCGGGGTGTACTGGGCTCGCCCG
AATTGACGAGAGGAAATGGA

Downstream 100 bases:

>100_bases
TGATCACGCTGTATCATTGCGACGGCGCCCGCTCGTTCCGCCCGCTGTGGATGCTGGAGGAGCTCGGGGCCAACTACGAA
TTGAAGATGCTGCCGTTCCC

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLFTADHDEPRRILQKFIAAEINPHVDEWEEAGIFPAHELFKKLGDLGFLGLNKPVEFGGQGLDYSYALMMAEELGAINC
GAIPMAIGVQTDMATPALARFGSDTVRKEFLAPAISGDYVACIGVSEPGAGSDVASIKTQARADGDDYVINGGKMWITNG
TQADFICLLANTSDGPVHRNKSLICVPMKSRGVQVARKLDKMGMRSSDTAQIFFDNVRVPKRNRVGEEGMGFTYQMMQFQ
EERLWAGAACLKAHEAIINATIEYTRNRKAFGRSILDNQVVHFRLAELQTEVELLRALTYQAAEALVAGEDVTRLATMVK
LKTGRLGRELTDACLQYWGGMGFMNETPVSRAYRDSRLSSIGGGADEVMLTILCKMMGTLPGMAKAGNA

Sequences:

>Translated_389_residues
MLFTADHDEPRRILQKFIAAEINPHVDEWEEAGIFPAHELFKKLGDLGFLGLNKPVEFGGQGLDYSYALMMAEELGAINC
GAIPMAIGVQTDMATPALARFGSDTVRKEFLAPAISGDYVACIGVSEPGAGSDVASIKTQARADGDDYVINGGKMWITNG
TQADFICLLANTSDGPVHRNKSLICVPMKSRGVQVARKLDKMGMRSSDTAQIFFDNVRVPKRNRVGEEGMGFTYQMMQFQ
EERLWAGAACLKAHEAIINATIEYTRNRKAFGRSILDNQVVHFRLAELQTEVELLRALTYQAAEALVAGEDVTRLATMVK
LKTGRLGRELTDACLQYWGGMGFMNETPVSRAYRDSRLSSIGGGADEVMLTILCKMMGTLPGMAKAGNA
>Mature_389_residues
MLFTADHDEPRRILQKFIAAEINPHVDEWEEAGIFPAHELFKKLGDLGFLGLNKPVEFGGQGLDYSYALMMAEELGAINC
GAIPMAIGVQTDMATPALARFGSDTVRKEFLAPAISGDYVACIGVSEPGAGSDVASIKTQARADGDDYVINGGKMWITNG
TQADFICLLANTSDGPVHRNKSLICVPMKSRGVQVARKLDKMGMRSSDTAQIFFDNVRVPKRNRVGEEGMGFTYQMMQFQ
EERLWAGAACLKAHEAIINATIEYTRNRKAFGRSILDNQVVHFRLAELQTEVELLRALTYQAAEALVAGEDVTRLATMVK
LKTGRLGRELTDACLQYWGGMGFMNETPVSRAYRDSRLSSIGGGADEVMLTILCKMMGTLPGMAKAGNA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=34.2175066312997, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI4557233, Length=368, Percent_Identity=33.1521739130435, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=31.7073170731707, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI226958414, Length=333, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=33.5106382978723, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=33.5106382978723, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=27.7333333333333, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=29.3650793650794, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=30.8605341246291, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4557235, Length=337, Percent_Identity=30.8605341246291, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI21361497, Length=384, Percent_Identity=28.6458333333333, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI38505218, Length=364, Percent_Identity=26.9230769230769, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=26.8292682926829, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=26.8292682926829, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI7669494, Length=295, Percent_Identity=26.4406779661017, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4503943, Length=295, Percent_Identity=26.4406779661017, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI87081958, Length=347, Percent_Identity=31.9884726224784, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=26.7955801104972, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=54.0106951871658, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=54.2553191489362, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=32.7272727272727, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17538396, Length=368, Percent_Identity=31.7934782608696, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=30.7086614173228, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17534899, Length=366, Percent_Identity=31.4207650273224, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=29.287598944591, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=33.2116788321168, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=29.041095890411, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=363, Percent_Identity=30.0275482093664, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=32.9059829059829, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=265, Percent_Identity=30.9433962264151, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=331, Percent_Identity=27.7945619335347, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=27.3858921161826, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=26.9896193771626, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=373, Percent_Identity=23.5924932975871, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=25.8426966292135, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=31.266846361186, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=31.5363881401617, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21355753, Length=366, Percent_Identity=32.2404371584699, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=29.9465240641711, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=32.8042328042328, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=26.9121813031161, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI19920834, Length=286, Percent_Identity=28.3216783216783, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42466; Mature: 42466

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTADHDEPRRILQKFIAAEINPHVDEWEEAGIFPAHELFKKLGDLGFLGLNKPVEFGG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCEECCCCCHHCCC
QGLDYSYALMMAEELGAINCGAIPMAIGVQTDMATPALARFGSDTVRKEFLAPAISGDYV
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCCCEE
ACIGVSEPGAGSDVASIKTQARADGDDYVINGGKMWITNGTQADFICLLANTSDGPVHRN
EEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCCCCC
KSLICVPMKSRGVQVARKLDKMGMRSSDTAQIFFDNVRVPKRNRVGEEGMGFTYQMMQFQ
CCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EERLWAGAACLKAHEAIINATIEYTRNRKAFGRSILDNQVVHFRLAELQTEVELLRALTY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QAAEALVAGEDVTRLATMVKLKTGRLGRELTDACLQYWGGMGFMNETPVSRAYRDSRLSS
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IGGGADEVMLTILCKMMGTLPGMAKAGNA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLFTADHDEPRRILQKFIAAEINPHVDEWEEAGIFPAHELFKKLGDLGFLGLNKPVEFGG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCEECCCCCHHCCC
QGLDYSYALMMAEELGAINCGAIPMAIGVQTDMATPALARFGSDTVRKEFLAPAISGDYV
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCCCEE
ACIGVSEPGAGSDVASIKTQARADGDDYVINGGKMWITNGTQADFICLLANTSDGPVHRN
EEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCCCCC
KSLICVPMKSRGVQVARKLDKMGMRSSDTAQIFFDNVRVPKRNRVGEEGMGFTYQMMQFQ
CCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EERLWAGAACLKAHEAIINATIEYTRNRKAFGRSILDNQVVHFRLAELQTEVELLRALTY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QAAEALVAGEDVTRLATMVKLKTGRLGRELTDACLQYWGGMGFMNETPVSRAYRDSRLSS
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IGGGADEVMLTILCKMMGTLPGMAKAGNA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]