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The map label for this gene is mmgC [H]

Identifier: 146343641

GI number: 146343641

Start: 7148264

End: 7149403

Strand: Reverse

Name: mmgC [H]

Synonym: BRADO6881

Alternate gene names: 146343641

Gene position: 7149403-7148264 (Counterclockwise)

Preceding gene: 146343644

Following gene: 146343640

Centisome position: 95.88

GC content: 65.88

Gene sequence:

>1140_bases
ATGACGAAAAGCCCGTTCTATACGGCCGAGCACGAGGCCTTCCGCGACGTCATCAGGCGCTTTGTCGACAAGGAGATCGC
GCCATTCGCGAACGCCTGGGACGAGGCCGGCGAATTCCCGCGCACGCTGTATACGAAGGCGGCCGAGATCGGTCTGCTGG
GCCTGGGCTTTCCGGAAGAGTTCGGCGGTGTGGCCGCCGATCAGTTCATGAGGATCGTGTCGTCGCAGGAGCTGGCCAGG
GCCGGCATCGGCGGCGTCAGCGCCAGCCTGATGAGCCACAGCATCGGCGCGCCGCCGATCGCGCGCGCGGCACGGCCGGA
GGTGCGCGCGAAGGTGCTGCCGGAGATCCTGTCGGGACGCAAGATCTCGGCACTCGCGATCACCGAGCCGAGCGGCGGCT
CGGACGTCGCCAATCTCCGCACCAAGGCGGTGCGCGACGGCAATCATTACGTGGTGAGTGGCGAGAAGACGTTCATCACC
TCGGGCGTGCGCGCCGACTACATCACCGTCGCCGTGCGCACGGGTGGACCTGGGCCGGCGGGTGTCAGTCTGCTGCTCAT
TCCCGGCGACACGCCCGGGCTGACCCGCACCAGGCTGAACAAGATGGGCTGGTGGGCGTCGGATACCGCGACCCTGCATT
TCGACAATTGCCGCGTGCCGGCCGAGAACCTGATCGGCGAGGAGGGGCAGGGCTTCAAGCTGATCATGCACAATTTCAAC
AGCGAGCGGATGGGCATGGCGGCGAGCTGCACGGCGTTCGCCCGCGTCTGCCTCGACGATGCGATTGCGTATGCGAAAGA
GCGCCAGACCTTCGGCAAGCCGTTGGCGCAGCACCAGGTGATCCGGCACAAGCTGGTCGACATGGCGCAGCGCGTCGCGG
CCTCGCAGGCAATGCTGGAGATGCTGGCGTGGCGGCTCGAACAGGGTGATAATCCCGTTGCCGAGATCTGCATGATGAAG
AACCAGGCGACGCAGACGATGGCCTATTGCGCCTCCGAGGCGGTGCAGATTTTCGGCGGCGCGGGCTTCATGCGCGGCGT
CCGTGTCGAGCGGATCTATCGCGAGGTCAAGGTCAATGCGATCGGCGGCGGCACCGAGGAGATCATGAAGGACCTGGCAA
GCCGGCAGATGGGATTGTGA

Upstream 100 bases:

>100_bases
CGCTTGGCCGGGCGCGATTTCGGCAGTCAGCGCCTCGACGCAAGGCGATACCGCGGCTTCCGGTCATCCTTGCCGACGCA
GCAACCAGAGCCCGGCATCG

Downstream 100 bases:

>100_bases
CGAGTCGCGCGCCACGATCCATGGAGTTGCTCGGGCAGACGATCCCGATGCGGCCGTCCTTCGAGACGCCCGCCAAGAGG
CGGGCTCCTCAGGACGAGGG

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTKSPFYTAEHEAFRDVIRRFVDKEIAPFANAWDEAGEFPRTLYTKAAEIGLLGLGFPEEFGGVAADQFMRIVSSQELAR
AGIGGVSASLMSHSIGAPPIARAARPEVRAKVLPEILSGRKISALAITEPSGGSDVANLRTKAVRDGNHYVVSGEKTFIT
SGVRADYITVAVRTGGPGPAGVSLLLIPGDTPGLTRTRLNKMGWWASDTATLHFDNCRVPAENLIGEEGQGFKLIMHNFN
SERMGMAASCTAFARVCLDDAIAYAKERQTFGKPLAQHQVIRHKLVDMAQRVAASQAMLEMLAWRLEQGDNPVAEICMMK
NQATQTMAYCASEAVQIFGGAGFMRGVRVERIYREVKVNAIGGGTEEIMKDLASRQMGL

Sequences:

>Translated_379_residues
MTKSPFYTAEHEAFRDVIRRFVDKEIAPFANAWDEAGEFPRTLYTKAAEIGLLGLGFPEEFGGVAADQFMRIVSSQELAR
AGIGGVSASLMSHSIGAPPIARAARPEVRAKVLPEILSGRKISALAITEPSGGSDVANLRTKAVRDGNHYVVSGEKTFIT
SGVRADYITVAVRTGGPGPAGVSLLLIPGDTPGLTRTRLNKMGWWASDTATLHFDNCRVPAENLIGEEGQGFKLIMHNFN
SERMGMAASCTAFARVCLDDAIAYAKERQTFGKPLAQHQVIRHKLVDMAQRVAASQAMLEMLAWRLEQGDNPVAEICMMK
NQATQTMAYCASEAVQIFGGAGFMRGVRVERIYREVKVNAIGGGTEEIMKDLASRQMGL
>Mature_378_residues
TKSPFYTAEHEAFRDVIRRFVDKEIAPFANAWDEAGEFPRTLYTKAAEIGLLGLGFPEEFGGVAADQFMRIVSSQELARA
GIGGVSASLMSHSIGAPPIARAARPEVRAKVLPEILSGRKISALAITEPSGGSDVANLRTKAVRDGNHYVVSGEKTFITS
GVRADYITVAVRTGGPGPAGVSLLLIPGDTPGLTRTRLNKMGWWASDTATLHFDNCRVPAENLIGEEGQGFKLIMHNFNS
ERMGMAASCTAFARVCLDDAIAYAKERQTFGKPLAQHQVIRHKLVDMAQRVAASQAMLEMLAWRLEQGDNPVAEICMMKN
QATQTMAYCASEAVQIFGGAGFMRGVRVERIYREVKVNAIGGGTEEIMKDLASRQMGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=32.9787234042553, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=33.7765957446808, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=33.7765957446808, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=32.1621621621622, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=32.5136612021858, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=28.8, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=31.8302387267904, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=28.8235294117647, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=28.1501340482574, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI76496475, Length=372, Percent_Identity=32.5268817204301, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI4557235, Length=372, Percent_Identity=32.5268817204301, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI7669494, Length=344, Percent_Identity=27.3255813953488, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4503943, Length=369, Percent_Identity=26.8292682926829, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI211971008, Length=311, Percent_Identity=27.6527331189711, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI48976061, Length=311, Percent_Identity=27.6527331189711, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38505218, Length=279, Percent_Identity=25.8064516129032, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87081958, Length=374, Percent_Identity=32.3529411764706, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=28.4530386740331, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=30.1158301158301, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=33.2446808510638, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=32.0209973753281, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=32.7823691460055, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=32.258064516129, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=372, Percent_Identity=29.8387096774194, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=31.129476584022, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=369, Percent_Identity=30.3523035230352, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=32.183908045977, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=30.2197802197802, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=358, Percent_Identity=29.3296089385475, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=33.5664335664336, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=290, Percent_Identity=27.2413793103448, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=32.3275862068966, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71982178, Length=261, Percent_Identity=26.4367816091954, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=336, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=238, Percent_Identity=27.7310924369748, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=36.1702127659575, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=30.4, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21356377, Length=365, Percent_Identity=28.7671232876712, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24646207, Length=362, Percent_Identity=30.6629834254144, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=31.4285714285714, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=30.3867403314917, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI19920834, Length=289, Percent_Identity=28.3737024221453, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41056; Mature: 40924

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00698 GLYCOSYL_HYDROL_F9_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSPFYTAEHEAFRDVIRRFVDKEIAPFANAWDEAGEFPRTLYTKAAEIGLLGLGFPEE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCHH
FGGVAADQFMRIVSSQELARAGIGGVSASLMSHSIGAPPIARAARPEVRAKVLPEILSGR
HCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCC
KISALAITEPSGGSDVANLRTKAVRDGNHYVVSGEKTFITSGVRADYITVAVRTGGPGPA
CEEEEEEECCCCCCHHHHHHHHHEECCCEEEEECCCEEEECCCCEEEEEEEEECCCCCCC
GVSLLLIPGDTPGLTRTRLNKMGWWASDTATLHFDNCRVPAENLIGEEGQGFKLIMHNFN
CEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCCEEEEEECCC
SERMGMAASCTAFARVCLDDAIAYAKERQTFGKPLAQHQVIRHKLVDMAQRVAASQAMLE
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAWRLEQGDNPVAEICMMKNQATQTMAYCASEAVQIFGGAGFMRGVRVERIYREVKVNA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
IGGGTEEIMKDLASRQMGL
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKSPFYTAEHEAFRDVIRRFVDKEIAPFANAWDEAGEFPRTLYTKAAEIGLLGLGFPEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCHH
FGGVAADQFMRIVSSQELARAGIGGVSASLMSHSIGAPPIARAARPEVRAKVLPEILSGR
HCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCC
KISALAITEPSGGSDVANLRTKAVRDGNHYVVSGEKTFITSGVRADYITVAVRTGGPGPA
CEEEEEEECCCCCCHHHHHHHHHEECCCEEEEECCCEEEECCCCEEEEEEEEECCCCCCC
GVSLLLIPGDTPGLTRTRLNKMGWWASDTATLHFDNCRVPAENLIGEEGQGFKLIMHNFN
CEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCCEEEEEECCC
SERMGMAASCTAFARVCLDDAIAYAKERQTFGKPLAQHQVIRHKLVDMAQRVAASQAMLE
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAWRLEQGDNPVAEICMMKNQATQTMAYCASEAVQIFGGAGFMRGVRVERIYREVKVNA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
IGGGTEEIMKDLASRQMGL
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]