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The map label for this gene is lig [H]

Identifier: 146343506

GI number: 146343506

Start: 6998599

End: 6999645

Strand: Direct

Name: lig [H]

Synonym: BRADO6738

Alternate gene names: 146343506

Gene position: 6998599-6999645 (Clockwise)

Preceding gene: 146343501

Following gene: 146343507

Centisome position: 93.86

GC content: 69.44

Gene sequence:

>1047_bases
ATGACTCCCATGCGCCCGCAAGACATCCTGCTGCCCGTCCCCTCCGGCCTCTGCTGCAAGGCCGGCGGCTTCCATATCGA
TCCCGTCCGCCCGGTCGAGCGGGCGCTGATCACGCATGGCCATTCCGACCACGCCCGCGCCGGGCACGGCGCCGTGCTGG
CGACGCAGGAAACGCTGGACATCATGCGGCTGCGCTATGGCGAGAACTTTGCCGGCAGCACGCAGGCGATCGGCTATGGC
GAGGAGATCAAGCTCGGCGACGTCAAGGTCAGCTTTCACCCCGCCGGCCACGTGCTCGGCTCGGCCCAGATCAAGGTGTC
CTCGGGCGGCACCTGCATCGTCGCGTCCGGCGACTACAAGGACGCGCGCGATCCGACCTGCGCGCCGTTCGAGCTGGTGC
AATGCGACGTGTTCATCACCGAGGCGACATTCGGCCTGCCGGTGTTCCGTCACGGCGACACGGCACTCGAGGTCAACAAG
CTGCTGGCCTCGGTGGCGCTGTTTCCCGAGCGCGCGCATCTCGTCGGCGCCTACTCGCTCGGCAAGGCGCAGCGCGTGAT
CGCGCTGATCCGCGAGGCCGGCTACGACGCGCCGATCTACCTGCATGGCGCGATGGAGAAGATCACGCGCTACTATCAGC
ACAAGGGCATCCCGCTCGGCGAGCTCAGGCCGGTGAAGGGCGTCAAGAAGGCCGAGCTCGCCGGCACCATTACCTTGGCC
CCGCCGAGCGCGACCTCCGACCTGTGGACGCGGCGCTTCCCCGATCCTGTCACCGCCTTCGCCTCGGGCTGGATGCGGGT
GCGCGCCCGCGCCCGCCAGCGCGGCGTCGAGCTGCCGCTGGTGATCTCGGATCATGCCGACTGGGACGGGCTGACCGCGA
CCATCGCCGCCACCGGCGCCGGCGAGGTCTGGGTGACGCACGGACAGGAGGACGCGCTGGTGCATTGGTGTCAGACCAAG
GGGCTCACGGCGCGGCCTCTCGATCTCGTCGGCTACGGCGACGAGGAGGAGAGCGAGGTGGTGGCGTCGGAGGGGGCCGA
GGCATGA

Upstream 100 bases:

>100_bases
CATCATCGAACGAGTCATTCCAAATGATGGATGCGCGGGTCAAGCCCGCGCATGACGAGCGCAGGATGGGACCGGCTGAA
TTTTCCGACGCGAGACCTAT

Downstream 100 bases:

>100_bases
ACCGCTTCGCCGAGCTGCTCGACCGCCTCGCCTATGAGCCCGGCCGCAACAACAAGCTGCGCCTGCTGACCTCGTATTTC
CGCGAGGTCGAGGACCCCGA

Product: putative metallo-hydrolase/oxidoreductase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTPMRPQDILLPVPSGLCCKAGGFHIDPVRPVERALITHGHSDHARAGHGAVLATQETLDIMRLRYGENFAGSTQAIGYG
EEIKLGDVKVSFHPAGHVLGSAQIKVSSGGTCIVASGDYKDARDPTCAPFELVQCDVFITEATFGLPVFRHGDTALEVNK
LLASVALFPERAHLVGAYSLGKAQRVIALIREAGYDAPIYLHGAMEKITRYYQHKGIPLGELRPVKGVKKAELAGTITLA
PPSATSDLWTRRFPDPVTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTK
GLTARPLDLVGYGDEEESEVVASEGAEA

Sequences:

>Translated_348_residues
MTPMRPQDILLPVPSGLCCKAGGFHIDPVRPVERALITHGHSDHARAGHGAVLATQETLDIMRLRYGENFAGSTQAIGYG
EEIKLGDVKVSFHPAGHVLGSAQIKVSSGGTCIVASGDYKDARDPTCAPFELVQCDVFITEATFGLPVFRHGDTALEVNK
LLASVALFPERAHLVGAYSLGKAQRVIALIREAGYDAPIYLHGAMEKITRYYQHKGIPLGELRPVKGVKKAELAGTITLA
PPSATSDLWTRRFPDPVTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTK
GLTARPLDLVGYGDEEESEVVASEGAEA
>Mature_347_residues
TPMRPQDILLPVPSGLCCKAGGFHIDPVRPVERALITHGHSDHARAGHGAVLATQETLDIMRLRYGENFAGSTQAIGYGE
EIKLGDVKVSFHPAGHVLGSAQIKVSSGGTCIVASGDYKDARDPTCAPFELVQCDVFITEATFGLPVFRHGDTALEVNKL
LASVALFPERAHLVGAYSLGKAQRVIALIREAGYDAPIYLHGAMEKITRYYQHKGIPLGELRPVKGVKKAELAGTITLAP
PSATSDLWTRRFPDPVTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTKG
LTARPLDLVGYGDEEESEVVASEGAEA

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37374; Mature: 37243

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMRPQDILLPVPSGLCCKAGGFHIDPVRPVERALITHGHSDHARAGHGAVLATQETLD
CCCCCCCCEEEECCCCCEECCCCEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHHHH
IMRLRYGENFAGSTQAIGYGEEIKLGDVKVSFHPAGHVLGSAQIKVSSGGTCIVASGDYK
HHHHHCCCCCCCCCCCCCCCCEEEECEEEEEEECCCCEECCEEEEEECCCEEEEECCCCC
DARDPTCAPFELVQCDVFITEATFGLPVFRHGDTALEVNKLLASVALFPERAHLVGAYSL
CCCCCCCCCEEEEEEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHEEEEEHHH
GKAQRVIALIREAGYDAPIYLHGAMEKITRYYQHKGIPLGELRPVKGVKKAELAGTITLA
CHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEEC
PPSATSDLWTRRFPDPVTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGA
CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCC
GEVWVTHGQEDALVHWCQTKGLTARPLDLVGYGDEEESEVVASEGAEA
CCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TPMRPQDILLPVPSGLCCKAGGFHIDPVRPVERALITHGHSDHARAGHGAVLATQETLD
CCCCCCCEEEECCCCCEECCCCEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHHHH
IMRLRYGENFAGSTQAIGYGEEIKLGDVKVSFHPAGHVLGSAQIKVSSGGTCIVASGDYK
HHHHHCCCCCCCCCCCCCCCCEEEECEEEEEEECCCCEECCEEEEEECCCEEEEECCCCC
DARDPTCAPFELVQCDVFITEATFGLPVFRHGDTALEVNKLLASVALFPERAHLVGAYSL
CCCCCCCCCEEEEEEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHEEEEEHHH
GKAQRVIALIREAGYDAPIYLHGAMEKITRYYQHKGIPLGELRPVKGVKKAELAGTITLA
CHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEEC
PPSATSDLWTRRFPDPVTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGA
CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCC
GEVWVTHGQEDALVHWCQTKGLTARPLDLVGYGDEEESEVVASEGAEA
CCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA