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The map label for this gene is gst [H]

Identifier: 146343488

GI number: 146343488

Start: 6975787

End: 6976401

Strand: Direct

Name: gst [H]

Synonym: BRADO6720

Alternate gene names: 146343488

Gene position: 6975787-6976401 (Clockwise)

Preceding gene: 146343482

Following gene: 146343495

Centisome position: 93.55

GC content: 62.11

Gene sequence:

>615_bases
ATGAAGCTTTATTATTCACCCGGCGCCTGCTCGCTGTCGCCCCATATCGCCCTGCTCGAAGCCGGCCTGCCCTATGATCT
GGTCAAGGTCGATCTGCGCGCCAAGACCCTGGAAAATGGCGACGATTATCTGAAGGTCAATCCGAAGGGCCAGGTGCCGG
CCCTGGGGCTGCCCAGCGGCGAAATCGTGACCGAGGGCCCGGTCATTGTCCAGATGATCGCCGACCAGGCCAAGGACAAG
GGCCTGGCCCCGGCGCGCGACAGCGGCGAGCGCTACAAGCTCCTGGAGTGGCTGAACTTCATCACCTCGGAGCTGCACAA
GAATTTCGGCCCGATGTTCTCGCCGGTGCTCGCCGACGACGCCAAGGCGTTCTTCAAGGACCGCGTGATGGGCAAGTTCA
AATACATCGACAGCCAGCTCGCCGGCCGCGACTATCTGATGGGCAGCCATTTCACCGTCGCCGACGGCTATCTGTTCACG
ATCCTGACCTGGGCGGACCGGATGAAGTTCGATCTGTCAGGAATGCCCAATCTCGTCGCCTACAAGAACCGGGTCGCGGC
GCGCCCGAAGGTGCAGGAAGCGCTGACGAAGGAAGGGCTGATGAAGGCGGGGTGA

Upstream 100 bases:

>100_bases
TGACGATTCCATGCAAATGCATTTAAGGGCGCAATGCATTCAGAGCGGATGAACCGCCCGGTCGGTTCCACCCAAAACGG
TCTCAAGGAGGGAATACAGG

Downstream 100 bases:

>100_bases
GTTCGCTTTTGATCGGCGATTTCTGGCACACTGCCGCAAAACCCTCAGTGTCATCCCCGCGAAAGCGGGGATCCATAACC
ACAGGGTGAAGTGTGTCGCG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKLYYSPGACSLSPHIALLEAGLPYDLVKVDLRAKTLENGDDYLKVNPKGQVPALGLPSGEIVTEGPVIVQMIADQAKDK
GLAPARDSGERYKLLEWLNFITSELHKNFGPMFSPVLADDAKAFFKDRVMGKFKYIDSQLAGRDYLMGSHFTVADGYLFT
ILTWADRMKFDLSGMPNLVAYKNRVAARPKVQEALTKEGLMKAG

Sequences:

>Translated_204_residues
MKLYYSPGACSLSPHIALLEAGLPYDLVKVDLRAKTLENGDDYLKVNPKGQVPALGLPSGEIVTEGPVIVQMIADQAKDK
GLAPARDSGERYKLLEWLNFITSELHKNFGPMFSPVLADDAKAFFKDRVMGKFKYIDSQLAGRDYLMGSHFTVADGYLFT
ILTWADRMKFDLSGMPNLVAYKNRVAARPKVQEALTKEGLMKAG
>Mature_204_residues
MKLYYSPGACSLSPHIALLEAGLPYDLVKVDLRAKTLENGDDYLKVNPKGQVPALGLPSGEIVTEGPVIVQMIADQAKDK
GLAPARDSGERYKLLEWLNFITSELHKNFGPMFSPVLADDAKAFFKDRVMGKFKYIDSQLAGRDYLMGSHFTVADGYLFT
ILTWADRMKFDLSGMPNLVAYKNRVAARPKVQEALTKEGLMKAG

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=200, Percent_Identity=48.5, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1787726, Length=206, Percent_Identity=28.1553398058252, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864594, Length=186, Percent_Identity=27.9569892473118, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22563; Mature: 22563

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYSPGACSLSPHIALLEAGLPYDLVKVDLRAKTLENGDDYLKVNPKGQVPALGLPSG
CEEEECCCCCCCCCCEEEEECCCCHHHEEEEHHHHHCCCCCCEEEECCCCCCCCCCCCCC
EIVTEGPVIVQMIADQAKDKGLAPARDSGERYKLLEWLNFITSELHKNFGPMFSPVLADD
CEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKAFFKDRVMGKFKYIDSQLAGRDYLMGSHFTVADGYLFTILTWADRMKFDLSGMPNLVA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCHHHHHHHHHHHHEECCCCCCHHHH
YKNRVAARPKVQEALTKEGLMKAG
HHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLYYSPGACSLSPHIALLEAGLPYDLVKVDLRAKTLENGDDYLKVNPKGQVPALGLPSG
CEEEECCCCCCCCCCEEEEECCCCHHHEEEEHHHHHCCCCCCEEEECCCCCCCCCCCCCC
EIVTEGPVIVQMIADQAKDKGLAPARDSGERYKLLEWLNFITSELHKNFGPMFSPVLADD
CEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKAFFKDRVMGKFKYIDSQLAGRDYLMGSHFTVADGYLFTILTWADRMKFDLSGMPNLVA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCHHHHHHHHHHHHEECCCCCCHHHH
YKNRVAARPKVQEALTKEGLMKAG
HHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]