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The map label for this gene is reg1 [H]

Identifier: 146343380

GI number: 146343380

Start: 6858369

End: 6859343

Strand: Direct

Name: reg1 [H]

Synonym: BRADO6609

Alternate gene names: 146343380

Gene position: 6858369-6859343 (Clockwise)

Preceding gene: 146343377

Following gene: 146343382

Centisome position: 91.98

GC content: 71.69

Gene sequence:

>975_bases
GTGCACCCGTCGACGGTCTCGCGCGCGCTCAGCCCGGCCATGAAGCATCTGGTCGCGACGGATGTCGCCGACCGTATCCA
GGCCGCTGCCAACGCCATCGGCTACCGGCTCAACATGGCGGCCAAGGGGTTGCGCACCGGGCGCAGCGGCCTGATCGGCG
TGCTGGCGCCCGATATCGCCGACCCCGGCTTTCCGCCGGTGCTCTCCGGCATCGCGGATCACCTCAATGCCGAGGGCTAT
GCGACGATCGTCGTCGACGTCGGCAGCAAGGGCTCGGAGCAGGATCTGGTCGATCGCCTGATCGCGCGCGGGGTCGACGG
CCTGGTGCTGGCGACGGTGAGCTTGCGCGACGATGTCGTAAAGCATTGTCTCGATGCGGCGCTGCCGGTCGTACTGGTCA
ATCGCGTCGATGGCGCGAGCCAGTTGCCATCAGCGGCCAGCGATGACGCGGCGGGCATGCGGCTTGCGGTCGAGCATCTC
GTGGCGCTCGGCCACCAGCGGATCGGCCACGTCGCCGGCCCGCAGGAGATCTCGACCGGCGCGCGCCGGCGGGCCGGCTT
CGAGGCCAGCGCCAGGGATGCGGGCCTGTCCGCCCGCCACGCGCCGGTCGAGGTCGCTGACTCCTACACGCGCGCGGCCG
GCCGCGAGGCTGCGCTGCGCCTCCTGACGCGCCGGACGCGGCCGACCGCGATCGTCGCCGCCAATGATTTGCTGGCGCTC
GGCGTCTATGACGCGCTCGCCGCCCGCGGCCTCGCCTGCCCCGGCGACGTGTCGGTGGTCGGCCACAACGACATGCCGTT
CGTCGACATGGTCTCGCCGCCGCTCACCACGGTGCGGATCGCCCAGCGCGACATGGGGGAAGCCGCAGCGCGATTGCTGC
TGGCGCGCATTGCGCGCCATGAGGTCACGGACGAGCATGTCGTGCTGGCGCCGCAGCTCATCATCCGCGGATCGACGGCG
CAGCCGCGGCCCTGA

Upstream 100 bases:

>100_bases
TCAGAGGCTGGACATGGAGCAGACATCGCGACCGGCGAGACGGCCGCAGGCAACGGCATCCGCCCGCCCGACGATCAAGG
ACGTGGCCGCCCGATGCGGC

Downstream 100 bases:

>100_bases
TCAGCGCAGACGTGCCCGCGTGATCACCTGCCCAGCGCGCGCATTCTGGTGCGCCCCCTGCCACCACGTCAGCGCGCCGT
TGACGACGACCGCGTCGATG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MHPSTVSRALSPAMKHLVATDVADRIQAAANAIGYRLNMAAKGLRTGRSGLIGVLAPDIADPGFPPVLSGIADHLNAEGY
ATIVVDVGSKGSEQDLVDRLIARGVDGLVLATVSLRDDVVKHCLDAALPVVLVNRVDGASQLPSAASDDAAGMRLAVEHL
VALGHQRIGHVAGPQEISTGARRRAGFEASARDAGLSARHAPVEVADSYTRAAGREAALRLLTRRTRPTAIVAANDLLAL
GVYDALAARGLACPGDVSVVGHNDMPFVDMVSPPLTTVRIAQRDMGEAAARLLLARIARHEVTDEHVVLAPQLIIRGSTA
QPRP

Sequences:

>Translated_324_residues
MHPSTVSRALSPAMKHLVATDVADRIQAAANAIGYRLNMAAKGLRTGRSGLIGVLAPDIADPGFPPVLSGIADHLNAEGY
ATIVVDVGSKGSEQDLVDRLIARGVDGLVLATVSLRDDVVKHCLDAALPVVLVNRVDGASQLPSAASDDAAGMRLAVEHL
VALGHQRIGHVAGPQEISTGARRRAGFEASARDAGLSARHAPVEVADSYTRAAGREAALRLLTRRTRPTAIVAANDLLAL
GVYDALAARGLACPGDVSVVGHNDMPFVDMVSPPLTTVRIAQRDMGEAAARLLLARIARHEVTDEHVVLAPQLIIRGSTA
QPRP
>Mature_324_residues
MHPSTVSRALSPAMKHLVATDVADRIQAAANAIGYRLNMAAKGLRTGRSGLIGVLAPDIADPGFPPVLSGIADHLNAEGY
ATIVVDVGSKGSEQDLVDRLIARGVDGLVLATVSLRDDVVKHCLDAALPVVLVNRVDGASQLPSAASDDAAGMRLAVEHL
VALGHQRIGHVAGPQEISTGARRRAGFEASARDAGLSARHAPVEVADSYTRAAGREAALRLLTRRTRPTAIVAANDLLAL
GVYDALAARGLACPGDVSVVGHNDMPFVDMVSPPLTTVRIAQRDMGEAAARLLLARIARHEVTDEHVVLAPQLIIRGSTA
QPRP

Specific function: Transcription repressor involved in control of expression of alpha-amylase and chitinase genes and of actinorhodin production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=317, Percent_Identity=29.9684542586751, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790194, Length=324, Percent_Identity=27.4691358024691, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=25.9375, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=29.1525423728814, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787906, Length=325, Percent_Identity=28.3076923076923, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786540, Length=324, Percent_Identity=29.6296296296296, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789202, Length=320, Percent_Identity=26.5625, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=27.7027027027027, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=28.6604361370716, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786268, Length=287, Percent_Identity=21.2543554006969, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=24.375, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789456, Length=163, Percent_Identity=28.8343558282209, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33803; Mature: 33803

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPSTVSRALSPAMKHLVATDVADRIQAAANAIGYRLNMAAKGLRTGRSGLIGVLAPDIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DPGFPPVLSGIADHLNAEGYATIVVDVGSKGSEQDLVDRLIARGVDGLVLATVSLRDDVV
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHH
KHCLDAALPVVLVNRVDGASQLPSAASDDAAGMRLAVEHLVALGHQRIGHVAGPQEISTG
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARRRAGFEASARDAGLSARHAPVEVADSYTRAAGREAALRLLTRRTRPTAIVAANDLLAL
HHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
GVYDALAARGLACPGDVSVVGHNDMPFVDMVSPPLTTVRIAQRDMGEAAARLLLARIARH
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVTDEHVVLAPQLIIRGSTAQPRP
CCCCCEEEECCHHEEECCCCCCCC
>Mature Secondary Structure
MHPSTVSRALSPAMKHLVATDVADRIQAAANAIGYRLNMAAKGLRTGRSGLIGVLAPDIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DPGFPPVLSGIADHLNAEGYATIVVDVGSKGSEQDLVDRLIARGVDGLVLATVSLRDDVV
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHH
KHCLDAALPVVLVNRVDGASQLPSAASDDAAGMRLAVEHLVALGHQRIGHVAGPQEISTG
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARRRAGFEASARDAGLSARHAPVEVADSYTRAAGREAALRLLTRRTRPTAIVAANDLLAL
HHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
GVYDALAARGLACPGDVSVVGHNDMPFVDMVSPPLTTVRIAQRDMGEAAARLLLARIARH
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVTDEHVVLAPQLIIRGSTAQPRP
CCCCCEEEECCHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9335287 [H]