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The map label for this gene is htpG [H]

Identifier: 146343100

GI number: 146343100

Start: 6537491

End: 6539359

Strand: Reverse

Name: htpG [H]

Synonym: BRADO6296

Alternate gene names: 146343100

Gene position: 6539359-6537491 (Counterclockwise)

Preceding gene: 146343101

Following gene: 146343098

Centisome position: 87.7

GC content: 65.33

Gene sequence:

>1869_bases
ATGACCGACACCGCCACCGTTAGCCATTCCTTCCAGGCCGAAGTCTCCGAGTTGCTGCACCTGATGGTGCACTCGGTCTA
CTCCGAGACCGACATCTTTTTACGCGAATTGATTTCGAACGCCTCCGACGCCTGTGACAAGCTGCGCTACGAGGCGATCG
CCAGGCCGGAGCTGATCGGCGACGGCGAGCCGCCGCAGATCCGCATCATTCCCGACAAGGCAGCCACCACCCTGACCATC
GCCGACAGCGGCATCGGCATGGACCGCCATGAGCTGATCGACCATCTCGGCACCATTGCCCGCTCCGGGACCAAGGCGTT
CGTGCAGAAGCTCGCCGAGGCCAAGGACGGCACCGGCCTGATCGGCCAGTTCGGCGTTGGCTTCTACTCCGCCTTCATGG
TCGCCGACCGCATCACCGTGATCAGCCGCCGCGCCGGCGGCAGCGAAGTCTGGACCTGGACCTCGTCGGGCGGCGCCGGC
TTCGAGGTCGCACCGGCCTCCGAGGAGGACGCCCAGCGGGTCACGCGTGGCACCGAGATCGTGCTGCACCTCAAGGACGA
CGCCAAGAAATATCTCGAGACTTATGAGATCGAGCGCATCGTCACCGCCTATTCCGACAACATCCAGTTCCCGATCATGC
TAGTGCAGGCCGAGGGCGAGCCGCGCCAGATCAACTCGGCGAGCGCGCTGTGGCAGCGGTCGAAGTCGGAGCTGTCGGCC
GAAGACTACGCCAAGGCCTACAAGTCGATCGCCAACGCCTTCGACGAACCGGCGATGACGCTGCACTATCGCGCCGAGGG
CCGCTACTCCTACGCTGTGCTGCTGTTTGCGCCCTCGACCAAGCCGTTCGACCTGTTCGAGCCGGCGCGCAAGGGCAAGG
TCAAGCTCTATGTCCGTCGCGTCTTCATCACTGACGACGCCGATCTGATGCCGGCGTACTTGCGCTTCATCCGCGGCGTG
ATCGACAGCGAGGATCTTCCGCTGAATCTGTCGCGCGAGATGCTGCAGAACAATCCGCAGCTGGCGCAGATCCGCAAGGC
GGTGACGACGCGCGTGATCAGCGAGCTGGAGCAGCTTGCCGAGAAGGACGCGGCCAACTTCGACAAGATCTGGGACGCGT
TCGGCGCTGTCATCAAGGAAGGCCTCTACGAGGATTTCGAGCGCCGTGACAAGCTGCTGGCGCTGTCGCGCTTCACGACC
ACCTCGGGCGAGCGGCGCCCGCTGAAGCAGTATGTCGAGGGGCTCAAGGAGAACCAGACCGAGATCTACTTCCTGGTCGG
CGACAGCATCGAGCGGTTGAAGTCCAATCCGCGGCTGGAGGCCGCAAAGGCGCGCGGCGTCGAGGTGCTCTTGCTGACGG
ATCCGGTCGATGCGTTCTGGACCTCGGCGCGGCTGGAGTTCGACGGCAAGCCGCTGAAGTCGCTGAGCCAGGGCGACATC
AATTTCGATCCGATCCCGGTCACCGAGAAAGAGGCCGAGGACGAGGCCAAGCCGGCTGCCGACGAGGCCAACACGATCGC
GCTGATCAAGGCGAGCCTCGGTGACCACGTCACCGACGTGAAGGTCTCGACCCGGCTGACCACCAGCGCCTCGTGCCTGG
TGGCCGGCAGCCATGGGCCGGACCGCGAGCTGGAGCGCATTCTCTCGCAGCAGGCACGCGGCGCCCGCACCAAGCCGATC
CTAGAGATCAACCTGCGCCATCCGCTGGTGGTCGCCGTCGCCAAGGCGGCGGCCGACAAGGCCAAGGTCGACGATCTCTC
GTTCCTGCTGCTCGAGCAGGCGCAGATCCTCGACGGCGAACTGCCGGAGGATCCGGCGGCGTTCGCGGCGCGGCTCAACC
GGCTCGTGCTGCAGGGCGTGGCCGCGTGA

Upstream 100 bases:

>100_bases
AACGAGCATTGGCAGGGGGCGATCGAAGGCTTGATCGACGCCGTCGCCGCGCTATATCGACGGTCTCACCTTCATTGCAA
GCACGGGCCAACGCACGACG

Downstream 100 bases:

>100_bases
GACGGACTACGGCAGGCGCCGCCGCTATCGGGTGGCGCTCGCCTGCGCGGCGACGATCTTGCGCCAGCGCATCACCTCGG
CCCGGTAGGTCGAGGCATAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MTDTATVSHSFQAEVSELLHLMVHSVYSETDIFLRELISNASDACDKLRYEAIARPELIGDGEPPQIRIIPDKAATTLTI
ADSGIGMDRHELIDHLGTIARSGTKAFVQKLAEAKDGTGLIGQFGVGFYSAFMVADRITVISRRAGGSEVWTWTSSGGAG
FEVAPASEEDAQRVTRGTEIVLHLKDDAKKYLETYEIERIVTAYSDNIQFPIMLVQAEGEPRQINSASALWQRSKSELSA
EDYAKAYKSIANAFDEPAMTLHYRAEGRYSYAVLLFAPSTKPFDLFEPARKGKVKLYVRRVFITDDADLMPAYLRFIRGV
IDSEDLPLNLSREMLQNNPQLAQIRKAVTTRVISELEQLAEKDAANFDKIWDAFGAVIKEGLYEDFERRDKLLALSRFTT
TSGERRPLKQYVEGLKENQTEIYFLVGDSIERLKSNPRLEAAKARGVEVLLLTDPVDAFWTSARLEFDGKPLKSLSQGDI
NFDPIPVTEKEAEDEAKPAADEANTIALIKASLGDHVTDVKVSTRLTTSASCLVAGSHGPDRELERILSQQARGARTKPI
LEINLRHPLVVAVAKAAADKAKVDDLSFLLLEQAQILDGELPEDPAAFAARLNRLVLQGVAA

Sequences:

>Translated_622_residues
MTDTATVSHSFQAEVSELLHLMVHSVYSETDIFLRELISNASDACDKLRYEAIARPELIGDGEPPQIRIIPDKAATTLTI
ADSGIGMDRHELIDHLGTIARSGTKAFVQKLAEAKDGTGLIGQFGVGFYSAFMVADRITVISRRAGGSEVWTWTSSGGAG
FEVAPASEEDAQRVTRGTEIVLHLKDDAKKYLETYEIERIVTAYSDNIQFPIMLVQAEGEPRQINSASALWQRSKSELSA
EDYAKAYKSIANAFDEPAMTLHYRAEGRYSYAVLLFAPSTKPFDLFEPARKGKVKLYVRRVFITDDADLMPAYLRFIRGV
IDSEDLPLNLSREMLQNNPQLAQIRKAVTTRVISELEQLAEKDAANFDKIWDAFGAVIKEGLYEDFERRDKLLALSRFTT
TSGERRPLKQYVEGLKENQTEIYFLVGDSIERLKSNPRLEAAKARGVEVLLLTDPVDAFWTSARLEFDGKPLKSLSQGDI
NFDPIPVTEKEAEDEAKPAADEANTIALIKASLGDHVTDVKVSTRLTTSASCLVAGSHGPDRELERILSQQARGARTKPI
LEINLRHPLVVAVAKAAADKAKVDDLSFLLLEQAQILDGELPEDPAAFAARLNRLVLQGVAA
>Mature_621_residues
TDTATVSHSFQAEVSELLHLMVHSVYSETDIFLRELISNASDACDKLRYEAIARPELIGDGEPPQIRIIPDKAATTLTIA
DSGIGMDRHELIDHLGTIARSGTKAFVQKLAEAKDGTGLIGQFGVGFYSAFMVADRITVISRRAGGSEVWTWTSSGGAGF
EVAPASEEDAQRVTRGTEIVLHLKDDAKKYLETYEIERIVTAYSDNIQFPIMLVQAEGEPRQINSASALWQRSKSELSAE
DYAKAYKSIANAFDEPAMTLHYRAEGRYSYAVLLFAPSTKPFDLFEPARKGKVKLYVRRVFITDDADLMPAYLRFIRGVI
DSEDLPLNLSREMLQNNPQLAQIRKAVTTRVISELEQLAEKDAANFDKIWDAFGAVIKEGLYEDFERRDKLLALSRFTTT
SGERRPLKQYVEGLKENQTEIYFLVGDSIERLKSNPRLEAAKARGVEVLLLTDPVDAFWTSARLEFDGKPLKSLSQGDIN
FDPIPVTEKEAEDEAKPAADEANTIALIKASLGDHVTDVKVSTRLTTSASCLVAGSHGPDRELERILSQQARGARTKPIL
EINLRHPLVVAVAKAAADKAKVDDLSFLLLEQAQILDGELPEDPAAFAARLNRLVLQGVAA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=679, Percent_Identity=35.640648011782, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI155722983, Length=639, Percent_Identity=35.3677621283255, Blast_Score=352, Evalue=5e-97,
Organism=Homo sapiens, GI154146191, Length=413, Percent_Identity=36.5617433414044, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI20149594, Length=413, Percent_Identity=38.0145278450363, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI153792590, Length=413, Percent_Identity=36.5617433414044, Blast_Score=243, Evalue=4e-64,
Organism=Escherichia coli, GI1786679, Length=632, Percent_Identity=43.1962025316456, Blast_Score=477, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=38.6329866270431, Blast_Score=434, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=35.2154531946508, Blast_Score=374, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI115535205, Length=641, Percent_Identity=33.3853354134165, Blast_Score=308, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=427, Percent_Identity=37.2365339578454, Blast_Score=261, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6323840, Length=678, Percent_Identity=38.6430678466077, Blast_Score=431, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325016, Length=417, Percent_Identity=38.3693045563549, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21357739, Length=684, Percent_Identity=33.3333333333333, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24586016, Length=644, Percent_Identity=34.1614906832298, Blast_Score=334, Evalue=1e-91,
Organism=Drosophila melanogaster, GI17647529, Length=416, Percent_Identity=37.5, Blast_Score=258, Evalue=1e-68,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 68732; Mature: 68600

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTATVSHSFQAEVSELLHLMVHSVYSETDIFLRELISNASDACDKLRYEAIARPELIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
DGEPPQIRIIPDKAATTLTIADSGIGMDRHELIDHLGTIARSGTKAFVQKLAEAKDGTGL
CCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
IGQFGVGFYSAFMVADRITVISRRAGGSEVWTWTSSGGAGFEVAPASEEDAQRVTRGTEI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHCCCEE
VLHLKDDAKKYLETYEIERIVTAYSDNIQFPIMLVQAEGEPRQINSASALWQRSKSELSA
EEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCH
EDYAKAYKSIANAFDEPAMTLHYRAEGRYSYAVLLFAPSTKPFDLFEPARKGKVKLYVRR
HHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEE
VFITDDADLMPAYLRFIRGVIDSEDLPLNLSREMLQNNPQLAQIRKAVTTRVISELEQLA
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKDAANFDKIWDAFGAVIKEGLYEDFERRDKLLALSRFTTTSGERRPLKQYVEGLKENQT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
EIYFLVGDSIERLKSNPRLEAAKARGVEVLLLTDPVDAFWTSARLEFDGKPLKSLSQGDI
EEEEEECCCHHHHHCCCCEEHHHCCCCEEEEEECCHHHHHCCCEEEECCCCHHHHCCCCC
NFDPIPVTEKEAEDEAKPAADEANTIALIKASLGDHVTDVKVSTRLTTSASCLVAGSHGP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEECCCCC
DRELERILSQQARGARTKPILEINLRHPLVVAVAKAAADKAKVDDLSFLLLEQAQILDGE
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
LPEDPAAFAARLNRLVLQGVAA
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDTATVSHSFQAEVSELLHLMVHSVYSETDIFLRELISNASDACDKLRYEAIARPELIG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
DGEPPQIRIIPDKAATTLTIADSGIGMDRHELIDHLGTIARSGTKAFVQKLAEAKDGTGL
CCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
IGQFGVGFYSAFMVADRITVISRRAGGSEVWTWTSSGGAGFEVAPASEEDAQRVTRGTEI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHCCCEE
VLHLKDDAKKYLETYEIERIVTAYSDNIQFPIMLVQAEGEPRQINSASALWQRSKSELSA
EEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCH
EDYAKAYKSIANAFDEPAMTLHYRAEGRYSYAVLLFAPSTKPFDLFEPARKGKVKLYVRR
HHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEE
VFITDDADLMPAYLRFIRGVIDSEDLPLNLSREMLQNNPQLAQIRKAVTTRVISELEQLA
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKDAANFDKIWDAFGAVIKEGLYEDFERRDKLLALSRFTTTSGERRPLKQYVEGLKENQT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
EIYFLVGDSIERLKSNPRLEAAKARGVEVLLLTDPVDAFWTSARLEFDGKPLKSLSQGDI
EEEEEECCCHHHHHCCCCEEHHHCCCCEEEEEECCHHHHHCCCEEEECCCCHHHHCCCCC
NFDPIPVTEKEAEDEAKPAADEANTIALIKASLGDHVTDVKVSTRLTTSASCLVAGSHGP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEECCCCC
DRELERILSQQARGARTKPILEINLRHPLVVAVAKAAADKAKVDDLSFLLLEQAQILDGE
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
LPEDPAAFAARLNRLVLQGVAA
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]