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The map label for this gene is ftsW [H]

Identifier: 146342499

GI number: 146342499

Start: 5853638

End: 5854789

Strand: Reverse

Name: ftsW [H]

Synonym: BRADO5660

Alternate gene names: 146342499

Gene position: 5854789-5853638 (Counterclockwise)

Preceding gene: 146342500

Following gene: 146342498

Centisome position: 78.52

GC content: 66.67

Gene sequence:

>1152_bases
ATGCTCTCCCGTGAAGAACGCAATCCGCTGTCGGACTGGTGGTGGACCGTCGACAAGCCGCTGCTGGGCTCGATCCTGGC
GCTGATGCTGTGCGGGGTGATCCTGTCGCTGGCGGCGAGTCCGCCGGTCGCGACTCGCATCGGGCTCGATCCGTTCCACT
TCTTCAACCGTCACGTCCTGTTCCTGTTGCCGTCCTTCGTCGTGCTGATCGGCATCTCCTTCCTGTCCCCGCGGCAGATC
CGGCGCAGTGCGCTGGTGGTGTTCGCGATCGCGATCGTGCTGATCGTGTTGACGCTCGCGATCGGCCCGGAGGTGAAGGG
CTCGCGGCGCTGGATCACGCTGGTCGGCGTCAACATCCAGGCGTCGGAAGCGGCCAAGCCGGCCTTCGTCGTCGTCGCGG
CGTGGTTGTTCTCGGAATCGGCGCGTCGGCCGGACATGCCTGCGACCACGATGGCGCTGGTGCTCTTGCTGATGCTGGTG
TCGCTCCTGGTGATGGAGCCGGATTTCGGACAGACGATGCTGATCCTGATGGTCTGGGGCTCGCTGTTCTTCATCGCCGG
CATGCGCATGATCTGGGTTGCGGGCCTCGCCGGTGCCGCGGCGGCCGGCCTGTTCGGCGCCTATCTCCTGGTCCCGCACG
TCGCCGGGCGCATCAAGCGCTTCATGAATCCGGCCTCGGGCGACACCTTCCAGGTCGACACTGCGATGGAGGCCTTCTCC
AATGGCGGCTGGTTCGGGCTCGGGCCGGGCGAGGGCATCGCCAAGCGCAGCCTGCCGGACAGCCACACCGACTTCGTCTT
CGCCGTCGCCGCCGAGGAGTTTGGCATCATCCTCTGCCTGGCGCTGGTCGCGCTGTTCGGCTTCATCGTCATCCGCACGC
TGTCGCGGGCCTATGCCAGCGAGGACGGTTTTTCGCGCTTCGCGGCCTCGGGCCTCGCGATCCTGTTCGGCATCCAGGCG
GCCATCAACATCTCGGTCAACCTGCAGCTCATCCCGGCCAAGGGCATGACCTTGCCGTTCATCTCCTATGGCGGCTCCTC
GATCGTCTCGCTGGCCTATGGCGTCGGCATGATGCTGGCGCTGACGCGGCAGCGGCCGCGGATCGAGGCCGAGGTCACGG
ATGCCGCGGGGACGCTACGCACCTACGCCTGA

Upstream 100 bases:

>100_bases
GCGCGTCACGGCTTGTCCGGGACGACAGCGAGATTCTTAACCCTTCGATAACCATCCTGGGCGCCAATGGGCTGATTCCT
TCGGCTCAGGTGGTGGCCCG

Downstream 100 bases:

>100_bases
AGGTCCAGGTCCGGCCGGCTCGCAATGTCGACACATTGCCTGTAAACAAGCCCGCATGATCTCATCTGCGCCTCTCATTC
TGCTGGCCGCCGGCGGCACC

Product: essential cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLSREERNPLSDWWWTVDKPLLGSILALMLCGVILSLAASPPVATRIGLDPFHFFNRHVLFLLPSFVVLIGISFLSPRQI
RRSALVVFAIAIVLIVLTLAIGPEVKGSRRWITLVGVNIQASEAAKPAFVVVAAWLFSESARRPDMPATTMALVLLLMLV
SLLVMEPDFGQTMLILMVWGSLFFIAGMRMIWVAGLAGAAAAGLFGAYLLVPHVAGRIKRFMNPASGDTFQVDTAMEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAAEEFGIILCLALVALFGFIVIRTLSRAYASEDGFSRFAASGLAILFGIQA
AINISVNLQLIPAKGMTLPFISYGGSSIVSLAYGVGMMLALTRQRPRIEAEVTDAAGTLRTYA

Sequences:

>Translated_383_residues
MLSREERNPLSDWWWTVDKPLLGSILALMLCGVILSLAASPPVATRIGLDPFHFFNRHVLFLLPSFVVLIGISFLSPRQI
RRSALVVFAIAIVLIVLTLAIGPEVKGSRRWITLVGVNIQASEAAKPAFVVVAAWLFSESARRPDMPATTMALVLLLMLV
SLLVMEPDFGQTMLILMVWGSLFFIAGMRMIWVAGLAGAAAAGLFGAYLLVPHVAGRIKRFMNPASGDTFQVDTAMEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAAEEFGIILCLALVALFGFIVIRTLSRAYASEDGFSRFAASGLAILFGIQA
AINISVNLQLIPAKGMTLPFISYGGSSIVSLAYGVGMMLALTRQRPRIEAEVTDAAGTLRTYA
>Mature_383_residues
MLSREERNPLSDWWWTVDKPLLGSILALMLCGVILSLAASPPVATRIGLDPFHFFNRHVLFLLPSFVVLIGISFLSPRQI
RRSALVVFAIAIVLIVLTLAIGPEVKGSRRWITLVGVNIQASEAAKPAFVVVAAWLFSESARRPDMPATTMALVLLLMLV
SLLVMEPDFGQTMLILMVWGSLFFIAGMRMIWVAGLAGAAAAGLFGAYLLVPHVAGRIKRFMNPASGDTFQVDTAMEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAAEEFGIILCLALVALFGFIVIRTLSRAYASEDGFSRFAASGLAILFGIQA
AINISVNLQLIPAKGMTLPFISYGGSSIVSLAYGVGMMLALTRQRPRIEAEVTDAAGTLRTYA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=30.5263157894737, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786853, Length=314, Percent_Identity=30.2547770700637, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41210; Mature: 41210

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSREERNPLSDWWWTVDKPLLGSILALMLCGVILSLAASPPVATRIGLDPFHFFNRHVL
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHH
FLLPSFVVLIGISFLSPRQIRRSALVVFAIAIVLIVLTLAIGPEVKGSRRWITLVGVNIQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEE
ASEAAKPAFVVVAAWLFSESARRPDMPATTMALVLLLMLVSLLVMEPDFGQTMLILMVWG
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SLFFIAGMRMIWVAGLAGAAAAGLFGAYLLVPHVAGRIKRFMNPASGDTFQVDTAMEAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHC
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAAEEFGIILCLALVALFGFIVIRTLSRAYAS
CCCEEECCCCCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGFSRFAASGLAILFGIQAAINISVNLQLIPAKGMTLPFISYGGSSIVSLAYGVGMMLA
CCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCEECEEECCCHHHHHHHHHHHHHHH
LTRQRPRIEAEVTDAAGTLRTYA
HHCCCCCCEEEEHHHCCHHHCCC
>Mature Secondary Structure
MLSREERNPLSDWWWTVDKPLLGSILALMLCGVILSLAASPPVATRIGLDPFHFFNRHVL
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHH
FLLPSFVVLIGISFLSPRQIRRSALVVFAIAIVLIVLTLAIGPEVKGSRRWITLVGVNIQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEE
ASEAAKPAFVVVAAWLFSESARRPDMPATTMALVLLLMLVSLLVMEPDFGQTMLILMVWG
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SLFFIAGMRMIWVAGLAGAAAAGLFGAYLLVPHVAGRIKRFMNPASGDTFQVDTAMEAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHC
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAAEEFGIILCLALVALFGFIVIRTLSRAYAS
CCCEEECCCCCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGFSRFAASGLAILFGIQAAINISVNLQLIPAKGMTLPFISYGGSSIVSLAYGVGMMLA
CCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCEECEEECCCHHHHHHHHHHHHHHH
LTRQRPRIEAEVTDAAGTLRTYA
HHCCCCCCEEEEHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]