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The map label for this gene is vllY [H]

Identifier: 146342433

GI number: 146342433

Start: 5775453

End: 5777324

Strand: Reverse

Name: vllY [H]

Synonym: BRADO5592

Alternate gene names: 146342433

Gene position: 5777324-5775453 (Counterclockwise)

Preceding gene: 146342434

Following gene: 146342432

Centisome position: 77.48

GC content: 66.03

Gene sequence:

>1872_bases
ATGAACCAGCGCTCGATCGCAACGGTCTCCATCTCAGGTGCCCTCGACGAGAAGCTCAAGGCGATCGCCGCGGCCGGCTT
CGAACTGGTCGAGATCTTCGAAAACGATCTCGTCGCGTTCGGGATGCGGCCGCGGGAGATCGGGCAGATGTGCCGCGACC
TCGGGCTCGCGATCTGCGCCTATCAGCCGTTCCGCGATTTCGAGGGCATGCCGGAGCCGCAGCGCGCCCGCAACTTTATC
CGCGCCGAGCGCAAGTTCGACCTGATGCAGGAGCTCGGCACCGATCTGCTGCTGATCTGCAGCAACGTTTCGCCGCTGTC
GCTCGGCGGCATCGATCGCGCCGCCGCAGATTTCCATGAGCTCGGCGAGCGCGCCGCCAAGCGCGGCCTGCGCGTCGGCT
ACGAGGCGCTGGCCTGGGGCCGCCACGTCCACGACTATCGCGATGCGTGGGAGATCGTGCGCCGCGCCGATCACAAGGCG
ATCGGCGTCATCCTCGACAGCTTCCATGCGCTGGCCCCGTCGCTGCCGACCAATGCGATCCGCGCCATTCCCGCCGACAA
GATCTTCCTGGTGCAGTTGGCCGACGCGCCCAAGCTCGAGCTGGACGTGCTGTCCTGGAGCCGGCATTTCCGCAGCTTCC
CGGGGCAGGGCGACCTGCCCGTGGGCGACTTCATGGAGGCGGTCGCCGCGACCGGCTATTCCGGGCCGCTGTCGCTGGAG
ATCTTCAACGACCAGTTCCGCGCCGGCTCGGCACCGCGCACCGCGCTCGATGGCATGCGCTCGCTGCTGCTGCTGCAGGA
CGATCTTGCCGGGAAGATTCCGGCATCGTCCGCCGCACGCTTCGAGCCGCGCGTGAGAAGCCACGGCATCGGCTTCGTCG
AATTCGCCGTCAGCGAGGACAAAGCGGAATCGCTTGCGACGTTGTTCAGCCAACTCGGCTTCCGCAACACCGGGCGGCAT
CGTAGCAAGGCGGTGCAGCGCTGGTCGCAAGGCGCGATCGAGCTGGTGATCAATTGTGAGCCGGCGAGCTTCGCGCATTC
GCATTACGTCACGCACGGTCCCGGTGTCTGCGCGCTGGCGTTGGACGTCGACAGCGCCGACCGCGCGATGGCCCGGGCGC
AATCCTTGAAGACACGCACGTTCACGCAGCCGGTCGGTCCGGGCGAACTGGAGATTCCCGCGATCCACGGCGTCGGCGGC
AGCCTGCTGTATTTCCTCGACACCCACGGTCGCCATTGGGACGTCGACTTCGAGGCTGTCCCGAGCGACAAGGCAGCCGA
TCGCCTCCTCGCCGTCGATCACATCGCGCAATCGATGCCGCACGAGGAAATGCTGTCCTGGCTGCTGTTCTATGCCGGGA
TCATCGACTTCTCGCGCCTGCCGCAGATGGAGATCGCCGACCCACGCGGTCTCGTGCAGAGCCAGGCGATCGTCAACGGC
GATCGCAGCCTGCGCTTCATCCTCAACGGCTCCACGGCGACGCGCACGCTGTCGTCACGCTTCATCTCGGAGTTTTTCGG
CTCCGGCGTGCAGCACATCGCCTTCTCCTGCGATGACATCTTTGCAGCGGTGGCCGAGATGCGCGCCCGTGGGGCGGGCT
TTCTCGACATCCCCGACAATTACTACGACGATCTCGAAGCCAAATACGATCTGGCGCCCGAGACGATCGCCGCGCTCCGC
GGCAACGAGATCCTCTACGACCGCGACGGCGACGCCGAGTTCTTCCAGGTCTACACCCACATCTTCGAGGAGCGCTTCTT
CTTCGAGATCGTCCAGCGCCGCAACTACCAGGGTTTTGGCGCCCCCAATGCCGCGATCCGGCTCGCGGCGCAAGCACGCG
AGGTCCGGCCGGATACGATGCCGCGGCTTTAG

Upstream 100 bases:

>100_bases
AGCTCGGCCGCACCCGGATCGTCGACAAGGCTGATCGCGTGCTGGCCGATCCGCGCATCGGACAGCTGTTCCTGGGCGGC
GCGATGGAGGAGACGGCGGC

Downstream 100 bases:

>100_bases
AAGCCCCTGGGCTCAGTGATAAAACAAGAAAACATCGGGAGAAAACATGACGCGGATGAATTGGCGGCTGGCCTGCATGG
CCATGCTGATGGGCGCATGG

Product: putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter)

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MNQRSIATVSISGALDEKLKAIAAAGFELVEIFENDLVAFGMRPREIGQMCRDLGLAICAYQPFRDFEGMPEPQRARNFI
RAERKFDLMQELGTDLLLICSNVSPLSLGGIDRAAADFHELGERAAKRGLRVGYEALAWGRHVHDYRDAWEIVRRADHKA
IGVILDSFHALAPSLPTNAIRAIPADKIFLVQLADAPKLELDVLSWSRHFRSFPGQGDLPVGDFMEAVAATGYSGPLSLE
IFNDQFRAGSAPRTALDGMRSLLLLQDDLAGKIPASSAARFEPRVRSHGIGFVEFAVSEDKAESLATLFSQLGFRNTGRH
RSKAVQRWSQGAIELVINCEPASFAHSHYVTHGPGVCALALDVDSADRAMARAQSLKTRTFTQPVGPGELEIPAIHGVGG
SLLYFLDTHGRHWDVDFEAVPSDKAADRLLAVDHIAQSMPHEEMLSWLLFYAGIIDFSRLPQMEIADPRGLVQSQAIVNG
DRSLRFILNGSTATRTLSSRFISEFFGSGVQHIAFSCDDIFAAVAEMRARGAGFLDIPDNYYDDLEAKYDLAPETIAALR
GNEILYDRDGDAEFFQVYTHIFEERFFFEIVQRRNYQGFGAPNAAIRLAAQAREVRPDTMPRL

Sequences:

>Translated_623_residues
MNQRSIATVSISGALDEKLKAIAAAGFELVEIFENDLVAFGMRPREIGQMCRDLGLAICAYQPFRDFEGMPEPQRARNFI
RAERKFDLMQELGTDLLLICSNVSPLSLGGIDRAAADFHELGERAAKRGLRVGYEALAWGRHVHDYRDAWEIVRRADHKA
IGVILDSFHALAPSLPTNAIRAIPADKIFLVQLADAPKLELDVLSWSRHFRSFPGQGDLPVGDFMEAVAATGYSGPLSLE
IFNDQFRAGSAPRTALDGMRSLLLLQDDLAGKIPASSAARFEPRVRSHGIGFVEFAVSEDKAESLATLFSQLGFRNTGRH
RSKAVQRWSQGAIELVINCEPASFAHSHYVTHGPGVCALALDVDSADRAMARAQSLKTRTFTQPVGPGELEIPAIHGVGG
SLLYFLDTHGRHWDVDFEAVPSDKAADRLLAVDHIAQSMPHEEMLSWLLFYAGIIDFSRLPQMEIADPRGLVQSQAIVNG
DRSLRFILNGSTATRTLSSRFISEFFGSGVQHIAFSCDDIFAAVAEMRARGAGFLDIPDNYYDDLEAKYDLAPETIAALR
GNEILYDRDGDAEFFQVYTHIFEERFFFEIVQRRNYQGFGAPNAAIRLAAQAREVRPDTMPRL
>Mature_623_residues
MNQRSIATVSISGALDEKLKAIAAAGFELVEIFENDLVAFGMRPREIGQMCRDLGLAICAYQPFRDFEGMPEPQRARNFI
RAERKFDLMQELGTDLLLICSNVSPLSLGGIDRAAADFHELGERAAKRGLRVGYEALAWGRHVHDYRDAWEIVRRADHKA
IGVILDSFHALAPSLPTNAIRAIPADKIFLVQLADAPKLELDVLSWSRHFRSFPGQGDLPVGDFMEAVAATGYSGPLSLE
IFNDQFRAGSAPRTALDGMRSLLLLQDDLAGKIPASSAARFEPRVRSHGIGFVEFAVSEDKAESLATLFSQLGFRNTGRH
RSKAVQRWSQGAIELVINCEPASFAHSHYVTHGPGVCALALDVDSADRAMARAQSLKTRTFTQPVGPGELEIPAIHGVGG
SLLYFLDTHGRHWDVDFEAVPSDKAADRLLAVDHIAQSMPHEEMLSWLLFYAGIIDFSRLPQMEIADPRGLVQSQAIVNG
DRSLRFILNGSTATRTLSSRFISEFFGSGVQHIAFSCDDIFAAVAEMRARGAGFLDIPDNYYDDLEAKYDLAPETIAALR
GNEILYDRDGDAEFFQVYTHIFEERFFFEIVQRRNYQGFGAPNAAIRLAAQAREVRPDTMPRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI285002264, Length=285, Percent_Identity=27.3684210526316, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4504477, Length=285, Percent_Identity=27.3684210526316, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17555220, Length=282, Percent_Identity=25.886524822695, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17550752, Length=197, Percent_Identity=30.9644670050761, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667510, Length=321, Percent_Identity=26.1682242990654, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356105, Length=274, Percent_Identity=26.2773722627737, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 68962; Mature: 68962

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRSIATVSISGALDEKLKAIAAAGFELVEIFENDLVAFGMRPREIGQMCRDLGLAICA
CCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHCC
YQPFRDFEGMPEPQRARNFIRAERKFDLMQELGTDLLLICSNVSPLSLGGIDRAAADFHE
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
LGERAAKRGLRVGYEALAWGRHVHDYRDAWEIVRRADHKAIGVILDSFHALAPSLPTNAI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RAIPADKIFLVQLADAPKLELDVLSWSRHFRSFPGQGDLPVGDFMEAVAATGYSGPLSLE
HCCCCCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
IFNDQFRAGSAPRTALDGMRSLLLLQDDLAGKIPASSAARFEPRVRSHGIGFVEFAVSED
EECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCCEEEEECCHH
KAESLATLFSQLGFRNTGRHRSKAVQRWSQGAIELVINCEPASFAHSHYVTHGPGVCALA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCEECCCCEEEEE
LDVDSADRAMARAQSLKTRTFTQPVGPGELEIPAIHGVGGSLLYFLDTHGRHWDVDFEAV
EECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECEEECCCCCEEEEEECCCCEECCCCEEC
PSDKAADRLLAVDHIAQSMPHEEMLSWLLFYAGIIDFSRLPQMEIADPRGLVQSQAIVNG
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
DRSLRFILNGSTATRTLSSRFISEFFGSGVQHIAFSCDDIFAAVAEMRARGAGFLDIPDN
CCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
YYDDLEAKYDLAPETIAALRGNEILYDRDGDAEFFQVYTHIFEERFFFEIVQRRNYQGFG
HHHCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APNAAIRLAAQAREVRPDTMPRL
CCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNQRSIATVSISGALDEKLKAIAAAGFELVEIFENDLVAFGMRPREIGQMCRDLGLAICA
CCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHCC
YQPFRDFEGMPEPQRARNFIRAERKFDLMQELGTDLLLICSNVSPLSLGGIDRAAADFHE
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
LGERAAKRGLRVGYEALAWGRHVHDYRDAWEIVRRADHKAIGVILDSFHALAPSLPTNAI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RAIPADKIFLVQLADAPKLELDVLSWSRHFRSFPGQGDLPVGDFMEAVAATGYSGPLSLE
HCCCCCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
IFNDQFRAGSAPRTALDGMRSLLLLQDDLAGKIPASSAARFEPRVRSHGIGFVEFAVSED
EECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCCEEEEECCHH
KAESLATLFSQLGFRNTGRHRSKAVQRWSQGAIELVINCEPASFAHSHYVTHGPGVCALA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCEECCCCEEEEE
LDVDSADRAMARAQSLKTRTFTQPVGPGELEIPAIHGVGGSLLYFLDTHGRHWDVDFEAV
EECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECEEECCCCCEEEEEECCCCEECCCCEEC
PSDKAADRLLAVDHIAQSMPHEEMLSWLLFYAGIIDFSRLPQMEIADPRGLVQSQAIVNG
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
DRSLRFILNGSTATRTLSSRFISEFFGSGVQHIAFSCDDIFAAVAEMRARGAGFLDIPDN
CCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
YYDDLEAKYDLAPETIAALRGNEILYDRDGDAEFFQVYTHIFEERFFFEIVQRRNYQGFG
HHHCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APNAAIRLAAQAREVRPDTMPRL
CCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA