Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 146342431

GI number: 146342431

Start: 5772899

End: 5773822

Strand: Direct

Name: yafC [H]

Synonym: BRADO5590

Alternate gene names: 146342431

Gene position: 5772899-5773822 (Clockwise)

Preceding gene: 146342429

Following gene: 146342446

Centisome position: 77.42

GC content: 68.07

Gene sequence:

>924_bases
ATGGATAAATTGGACATTAGCCTCGTCAACATGCGCAGCTTCGTTCGGGTGGCCGAACGCGGCAGCCTGTCAGCGGTGGC
GCGTGAGCTCGGAGTCGGCCAATCCACCATCTCGCGCCATCTGCAGGAGCTGGAGGAGGCGATCGGCGTCCCGCTGCTCA
GCCGCACCACCCGCCGCGTGACCCTGACCGACGAAGGCAGCCGGTATTACGCGAACTGCGTCCAGATCCTCCGCCTGGTC
GAACAGGCCGGTGACGAGGCGCGCGGCGCGCGTGGCGCCGCCAGCGGCACGATCCGGATCTCCTGTACGGCGGCCTTCGG
CATCCTGCACATTACACGGCTCGTCTTCGCCTTCCAGGATCGCTACCCGGACATTGCGATCGATCTCAATCTCACCGACG
AGCGCATCGACCTTGTGCGCGAGGGTGTCGACATCGCGCTGCGCCTGGCTCCGCTCACCGACAGCTCGCTCAAGCTGCGG
TCGCTCGGCTACTCGCACCGGCTGCTGGTCGCTTCGCCCGACTACCTGGCGAAGCGCGGCACGCCGCGCACGCCGCAGGA
GCTGATCGGCCACGACGGCATCCGCATGACCAATGTCGCCGGCAGCGACGTCCTCGTCGTCATCGGACCCGGCGGCGAGC
GCCACGAGGTGCCGTTCAGGGGCTGCTTCCGCACCAATCATGGACTGGGTGTTCGCGAAGCCGTGCTGGCCGGGCGCGGC
ATCGGCGGCAGCCACGCATGGCTCGTCCACGACCTGATCGCGGCCGGCAGGCTTACGGTAATCCTGCCCGACCACCGTCT
GCCGTCGACTCCCCTCAACATGCTGATCGTGCCGGAGCGCGCCGGCATCGCGCGCGTGCGGCTGCTGATCGACTATCTCG
CCGAGGAGATCGTCCGGCTGCCGGGCATCCGCCCGGAGCCATGA

Upstream 100 bases:

>100_bases
GGACGTTCATGGCTTGGATCCTTTGCTGGAAACAGCCGGAACATAGACGCGCACCGATTTATCCGCTACATGACGTATAT
TGATAATACTATGCTGTATT

Downstream 100 bases:

>100_bases
TCCAAAGGCGACCGTTCAGAAGCCCTTGAAGGGTGAGCCGAGCTGGTCGAACAGCCGGATGCGATCGAGCTGCGGCACAG
GTCCGACGCCCACCTTGTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDKLDISLVNMRSFVRVAERGSLSAVARELGVGQSTISRHLQELEEAIGVPLLSRTTRRVTLTDEGSRYYANCVQILRLV
EQAGDEARGARGAASGTIRISCTAAFGILHITRLVFAFQDRYPDIAIDLNLTDERIDLVREGVDIALRLAPLTDSSLKLR
SLGYSHRLLVASPDYLAKRGTPRTPQELIGHDGIRMTNVAGSDVLVVIGPGGERHEVPFRGCFRTNHGLGVREAVLAGRG
IGGSHAWLVHDLIAAGRLTVILPDHRLPSTPLNMLIVPERAGIARVRLLIDYLAEEIVRLPGIRPEP

Sequences:

>Translated_307_residues
MDKLDISLVNMRSFVRVAERGSLSAVARELGVGQSTISRHLQELEEAIGVPLLSRTTRRVTLTDEGSRYYANCVQILRLV
EQAGDEARGARGAASGTIRISCTAAFGILHITRLVFAFQDRYPDIAIDLNLTDERIDLVREGVDIALRLAPLTDSSLKLR
SLGYSHRLLVASPDYLAKRGTPRTPQELIGHDGIRMTNVAGSDVLVVIGPGGERHEVPFRGCFRTNHGLGVREAVLAGRG
IGGSHAWLVHDLIAAGRLTVILPDHRLPSTPLNMLIVPERAGIARVRLLIDYLAEEIVRLPGIRPEP
>Mature_307_residues
MDKLDISLVNMRSFVRVAERGSLSAVARELGVGQSTISRHLQELEEAIGVPLLSRTTRRVTLTDEGSRYYANCVQILRLV
EQAGDEARGARGAASGTIRISCTAAFGILHITRLVFAFQDRYPDIAIDLNLTDERIDLVREGVDIALRLAPLTDSSLKLR
SLGYSHRLLVASPDYLAKRGTPRTPQELIGHDGIRMTNVAGSDVLVVIGPGGERHEVPFRGCFRTNHGLGVREAVLAGRG
IGGSHAWLVHDLIAAGRLTVILPDHRLPSTPLNMLIVPERAGIARVRLLIDYLAEEIVRLPGIRPEP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=34.1379310344828, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=32.3232323232323, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=27.719298245614, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=28.6689419795222, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=27.4834437086093, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=30.794701986755, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=27.9310344827586, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI157672245, Length=157, Percent_Identity=33.1210191082803, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=25.78125, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI145693105, Length=206, Percent_Identity=25.2427184466019, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=148, Percent_Identity=30.4054054054054, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788706, Length=200, Percent_Identity=26.5, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=151, Percent_Identity=29.1390728476821, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33543; Mature: 33543

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLDISLVNMRSFVRVAERGSLSAVARELGVGQSTISRHLQELEEAIGVPLLSRTTRRV
CCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEEE
TLTDEGSRYYANCVQILRLVEQAGDEARGARGAASGTIRISCTAAFGILHITRLVFAFQD
EEECCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC
RYPDIAIDLNLTDERIDLVREGVDIALRLAPLTDSSLKLRSLGYSHRLLVASPDYLAKRG
CCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCEEEEECCHHHHHCC
TPRTPQELIGHDGIRMTNVAGSDVLVVIGPGGERHEVPFRGCFRTNHGLGVREAVLAGRG
CCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHEEECCCCCCHHHHHHHCCC
IGGSHAWLVHDLIAAGRLTVILPDHRLPSTPLNMLIVPERAGIARVRLLIDYLAEEIVRL
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
PGIRPEP
CCCCCCC
>Mature Secondary Structure
MDKLDISLVNMRSFVRVAERGSLSAVARELGVGQSTISRHLQELEEAIGVPLLSRTTRRV
CCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEEE
TLTDEGSRYYANCVQILRLVEQAGDEARGARGAASGTIRISCTAAFGILHITRLVFAFQD
EEECCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC
RYPDIAIDLNLTDERIDLVREGVDIALRLAPLTDSSLKLRSLGYSHRLLVASPDYLAKRG
CCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCEEEEECCHHHHHCC
TPRTPQELIGHDGIRMTNVAGSDVLVVIGPGGERHEVPFRGCFRTNHGLGVREAVLAGRG
CCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHEEECCCCCCHHHHHHHCCC
IGGSHAWLVHDLIAAGRLTVILPDHRLPSTPLNMLIVPERAGIARVRLLIDYLAEEIVRL
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
PGIRPEP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]