Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 146342413

GI number: 146342413

Start: 5756374

End: 5757873

Strand: Reverse

Name: degP [H]

Synonym: BRADO5572

Alternate gene names: 146342413

Gene position: 5757873-5756374 (Counterclockwise)

Preceding gene: 146342414

Following gene: 146342408

Centisome position: 77.22

GC content: 67.6

Gene sequence:

>1500_bases
ATGACCGCAACCCTTGCTTTCCGCCGTCGACTGCGTCCGATCCTGACTGCGGCAGTGCTCGCCGCGGGCTGGGCGCTCGT
GCCGGCGCCGGCCTCGGCGCGGGGGCCGGAAGGGATCGCCGATGTCGCCGAAAAGGTGATCGATGCCGTCGTCAACATCT
CGACCTCGCAGACCGTCGAGGCCAAGGGCGGTGGAGGCGAGGGCCGCGGCGCCAATCCGCAGGTGCCGCCGGGCTCGCCG
TTCGAGGAGTTCTTCGACGACTTCTTCAAGAACCGCCGCGGTCCGGGCGGCCGAGGCGGCGCCGACAATTCGCCCCGCCG
CACCAACTCGCTCGGCTCCGGCTTCATCGTCGACGACAGCGGCATCGTGGTCACCAACAACCACGTCATCGCCGATGCCG
ACGAGATCAACGTGATCATGAACGACGGCACCAAGATCAAGGCCGAGCTGGTCGGCGTCGACAAGAAGACTGACCTCGCG
GTGCTGAAGTTCAAGCCGCCGCGGCAGCTCACCGTGGTCAAGTTCGGCGATTCCGACAAGCTCCGGCTCGGCGACTGGGT
GGTCGCGATCGGGAACCCGTTCAGCCTCGGCGGCACCGTCACCGCCGGCATCGTCTCGGCCAAGAACCGCGACATCTCGT
CGGGCCCCTATGACAGCTACATCCAGACCGACGCCGCCATCAACCGCGGCAATTCCGGCGGCCCGCTGTTCAACCTCGAC
GGCGAGGTCATCGGCGTCAACACGCTGATCATTTCGCCCTCGGGCGGCTCGATCGGCATCGGCTTCGCCGTGCCCTCGAA
GACCGTCGCCGGCGTCGTCGACCAGCTGCGCCAGTTCGGCGAACTGCGCCGCGGCTGGCTCGGCGTGCGCATCCAGGGCG
TCACCGACGAGATCGCCGAGAGCCTCAACATCAAGCCGGCGCGCGGCGCGCTGGTCGCCGGCGTCGACGACAAGGGCCCG
GCCAAGCCGGCCGGCATCGAGCCGGGCGACGTCGTCGTCAAGTTCGACGGCCACGACATCAAAGAGCCGAAGGACCTGTC
GCGCATCGTCGCCGACACCGCGGTCGGCAAGGAGGTCGACGTCGTCGTCATCCGCAAAGGCCAGGAGCAGACGCTCAAGG
TCAAGCTCGGCCGGCTCGAGGACAACGAGAAGGTTCAGCAGGCGGCGATCAAGAAGGACGAGCCGGCGGAGAAGCCGGTG
ACCCAGAAGGCGCTCGGGCTCGATCTTGCTGCTTTGTCGAAGGATCTGCGCACCCGCTACAAGATCAAGGACAGCGTCAA
GGGCGTCGTCGTCACCGGCGTCGACCAGGCCTCCGACGCCGCCGAGAAGCGGCTGTCGCCCGGCGACGTGATCGTCGAGG
TCGCCCAGGAGGCGGTCACCTCCGGCGCCGACATCAAGAAGCGCGTCGACCAGCTCAAGAAGGACGGCAAGAAGTCGGTG
CTGCTGCTGGTGTCCAACGCCGACGGCGAACTGCGCTTCGTGGCGCTGAGCTTGCAGTAG

Upstream 100 bases:

>100_bases
AATGATGAATCGGGCGCCGCGCGCCGGCGCGCTTGCGTCGCTGCCCGGTTCCGGCGCACTGTACCCGTTGAATTTTCCGC
CTTTTCTGGAGATCCGCCCG

Downstream 100 bases:

>100_bases
GGGCGCGGTCTTTCGTTCCAAACGCGGCTGCGTAGGGTGGGCAAAGGTGCGCCCACGTCTACGCGTGTTGTCTCTATCTC
TCACGCGCCGTGCCCACCAT

Product: putative Serine protease do-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTATLAFRRRLRPILTAAVLAAGWALVPAPASARGPEGIADVAEKVIDAVVNISTSQTVEAKGGGGEGRGANPQVPPGSP
FEEFFDDFFKNRRGPGGRGGADNSPRRTNSLGSGFIVDDSGIVVTNNHVIADADEINVIMNDGTKIKAELVGVDKKTDLA
VLKFKPPRQLTVVKFGDSDKLRLGDWVVAIGNPFSLGGTVTAGIVSAKNRDISSGPYDSYIQTDAAINRGNSGGPLFNLD
GEVIGVNTLIISPSGGSIGIGFAVPSKTVAGVVDQLRQFGELRRGWLGVRIQGVTDEIAESLNIKPARGALVAGVDDKGP
AKPAGIEPGDVVVKFDGHDIKEPKDLSRIVADTAVGKEVDVVVIRKGQEQTLKVKLGRLEDNEKVQQAAIKKDEPAEKPV
TQKALGLDLAALSKDLRTRYKIKDSVKGVVVTGVDQASDAAEKRLSPGDVIVEVAQEAVTSGADIKKRVDQLKKDGKKSV
LLLVSNADGELRFVALSLQ

Sequences:

>Translated_499_residues
MTATLAFRRRLRPILTAAVLAAGWALVPAPASARGPEGIADVAEKVIDAVVNISTSQTVEAKGGGGEGRGANPQVPPGSP
FEEFFDDFFKNRRGPGGRGGADNSPRRTNSLGSGFIVDDSGIVVTNNHVIADADEINVIMNDGTKIKAELVGVDKKTDLA
VLKFKPPRQLTVVKFGDSDKLRLGDWVVAIGNPFSLGGTVTAGIVSAKNRDISSGPYDSYIQTDAAINRGNSGGPLFNLD
GEVIGVNTLIISPSGGSIGIGFAVPSKTVAGVVDQLRQFGELRRGWLGVRIQGVTDEIAESLNIKPARGALVAGVDDKGP
AKPAGIEPGDVVVKFDGHDIKEPKDLSRIVADTAVGKEVDVVVIRKGQEQTLKVKLGRLEDNEKVQQAAIKKDEPAEKPV
TQKALGLDLAALSKDLRTRYKIKDSVKGVVVTGVDQASDAAEKRLSPGDVIVEVAQEAVTSGADIKKRVDQLKKDGKKSV
LLLVSNADGELRFVALSLQ
>Mature_498_residues
TATLAFRRRLRPILTAAVLAAGWALVPAPASARGPEGIADVAEKVIDAVVNISTSQTVEAKGGGGEGRGANPQVPPGSPF
EEFFDDFFKNRRGPGGRGGADNSPRRTNSLGSGFIVDDSGIVVTNNHVIADADEINVIMNDGTKIKAELVGVDKKTDLAV
LKFKPPRQLTVVKFGDSDKLRLGDWVVAIGNPFSLGGTVTAGIVSAKNRDISSGPYDSYIQTDAAINRGNSGGPLFNLDG
EVIGVNTLIISPSGGSIGIGFAVPSKTVAGVVDQLRQFGELRRGWLGVRIQGVTDEIAESLNIKPARGALVAGVDDKGPA
KPAGIEPGDVVVKFDGHDIKEPKDLSRIVADTAVGKEVDVVVIRKGQEQTLKVKLGRLEDNEKVQQAAIKKDEPAEKPVT
QKALGLDLAALSKDLRTRYKIKDSVKGVVVTGVDQASDAAEKRLSPGDVIVEVAQEAVTSGADIKKRVDQLKKDGKKSVL
LLVSNADGELRFVALSLQ

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=259, Percent_Identity=37.4517374517375, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI4506141, Length=277, Percent_Identity=35.7400722021661, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI24308541, Length=257, Percent_Identity=38.5214007782101, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI7019477, Length=289, Percent_Identity=37.0242214532872, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1786356, Length=484, Percent_Identity=36.7768595041322, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789629, Length=466, Percent_Identity=35.6223175965665, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789630, Length=272, Percent_Identity=38.9705882352941, Blast_Score=163, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646839, Length=286, Percent_Identity=34.965034965035, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52475; Mature: 52344

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLAFRRRLRPILTAAVLAAGWALVPAPASARGPEGIADVAEKVIDAVVNISTSQTVE
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
AKGGGGEGRGANPQVPPGSPFEEFFDDFFKNRRGPGGRGGADNSPRRTNSLGSGFIVDDS
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCC
GIVVTNNHVIADADEINVIMNDGTKIKAELVGVDKKTDLAVLKFKPPRQLTVVKFGDSDK
CEEEECCEEEECCCCEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCC
LRLGDWVVAIGNPFSLGGTVTAGIVSAKNRDISSGPYDSYIQTDAAINRGNSGGPLFNLD
EEECCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCHHCCHHHHCCCCCCCCEEECC
GEVIGVNTLIISPSGGSIGIGFAVPSKTVAGVVDQLRQFGELRRGWLGVRIQGVTDEIAE
CCEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHH
SLNIKPARGALVAGVDDKGPAKPAGIEPGDVVVKFDGHDIKEPKDLSRIVADTAVGKEVD
HCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVIRKGQEQTLKVKLGRLEDNEKVQQAAIKKDEPAEKPVTQKALGLDLAALSKDLRTRY
EEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHH
KIKDSVKGVVVTGVDQASDAAEKRLSPGDVIVEVAQEAVTSGADIKKRVDQLKKDGKKSV
HHHCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
LLLVSNADGELRFVALSLQ
EEEEECCCCCEEEEEEEEC
>Mature Secondary Structure 
TATLAFRRRLRPILTAAVLAAGWALVPAPASARGPEGIADVAEKVIDAVVNISTSQTVE
CCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
AKGGGGEGRGANPQVPPGSPFEEFFDDFFKNRRGPGGRGGADNSPRRTNSLGSGFIVDDS
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCC
GIVVTNNHVIADADEINVIMNDGTKIKAELVGVDKKTDLAVLKFKPPRQLTVVKFGDSDK
CEEEECCEEEECCCCEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCC
LRLGDWVVAIGNPFSLGGTVTAGIVSAKNRDISSGPYDSYIQTDAAINRGNSGGPLFNLD
EEECCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCHHCCHHHHCCCCCCCCEEECC
GEVIGVNTLIISPSGGSIGIGFAVPSKTVAGVVDQLRQFGELRRGWLGVRIQGVTDEIAE
CCEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHH
SLNIKPARGALVAGVDDKGPAKPAGIEPGDVVVKFDGHDIKEPKDLSRIVADTAVGKEVD
HCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVIRKGQEQTLKVKLGRLEDNEKVQQAAIKKDEPAEKPVTQKALGLDLAALSKDLRTRY
EEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHH
KIKDSVKGVVVTGVDQASDAAEKRLSPGDVIVEVAQEAVTSGADIKKRVDQLKKDGKKSV
HHHCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
LLLVSNADGELRFVALSLQ
EEEEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]