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The map label for this gene is fixC [H]

Identifier: 146342232

GI number: 146342232

Start: 5589870

End: 5591177

Strand: Reverse

Name: fixC [H]

Synonym: BRADO5384

Alternate gene names: 146342232

Gene position: 5591177-5589870 (Counterclockwise)

Preceding gene: 146342233

Following gene: 146342231

Centisome position: 74.98

GC content: 63.84

Gene sequence:

>1308_bases
ATGATCGAGGAACGTTTCGACGCGATCGTCGTGGGCGCCGGCATGGCCGGCAATGCGGCTGCGCTGACCATGGCCCAGCG
CGGCATGAAGGTCTTGCAGCTCGAGCGCGGCGAGTATTCCGGCTCGAAGAACGTGCAGGGCGCCATTCTCTATGCCGACA
TGCTCGAGAAGCTGATCCCGGATTTCCGCGAGGAAGCGCCGCTGGAGCGGCACCTCGTCGAGCAGCGCTTCTGGATGCTC
GACGACAAGTCCCATGTCGGCCTGCACTACAAGTCGGACGACTTCAACGAGGAGAAGCCGAACCGCTACACCATCATCCG
CGCCCAGTTCGACAAATGGTTCTCGTCCAAGGTCAAGGAAGCCGGCGCCACCGTGCTGTGCGAGACCACGGTGACGGAGC
TGGCGCAGGACGCCTATGGCAAGGTGATCGGCGTCAAGACCGACCGCCGCGACGGTGAGATCCATGCCGACGTGGTCGTG
CTGGCCGAGGGCGTCAACGGCCTGCTCGGTACACGCGCCGGCTTGCGCGAGCGGCCGAAGCCGGAGAACGTCGCGCTCGC
GGTCAAGGAGATGCACTTCCTGCCGCGCGAGACCATCGAGGCCCGCTTCAACCTCAAGGGCGACGAGGGCGCGGTCATCG
AGGCCGCAGGGACGATCTCCCGCGGCATGACCGGCATGGGCTTCATCTACTCCAACAAGGAGTGCATCTCGCTTGGTATC
GGCTGCCTCGTGTCCGACTTCCAGAAGACCGGCGAGACGCCTTATGGATTGCTGGAGCGCTTCAAGCAGCATCCGTCGGT
CGCGCCGCTGATCGAGGGCTCCGAGGTGAAGGAGTACTCGGCGCATCTGATTCCTGAGGGCGGCTACAACGCGATCCCGC
AGCTCTGCGGCGACGGCTGGGTCGTGGTCGGCGACGCCGCCCAGCTCAACAACGCGATCCACCGCGAAGGCTCCAACCTC
GCCATGACCTCAGGGCGCATCGCCGCCGAGGCGATCTTCCAGGTCAAGTCGCGCCGCGATCCGATGACCAAGGAGAACCT
CGCGCTCTACAAGAAGATGCTGGAAGAGTCCTTCGTCATCAAGGATCTGAAGAAGTACAAGGACATGCCGGCGCTGCTGC
ACAACCAGTCGCAGAACTTCTTCCTCACCTATCCGCAGCTGGTCTCCAAGGCGATGCAGAACTTCGTGCGCGTGGACGGC
ACGCCGAAGAAGGAGAAGGAGAGCAGCATGCTGCGGTCCTTCGTGAGTGCGAGGTCGTGGACGGGCCTGTTCGGCGATGC
CTTCAAGTTCGCCCGGGCGTGGCGCTAA

Upstream 100 bases:

>100_bases
GCGATCCGGCTGCTGCCGGCGCTCACCGAAGCATTCCGCGCGCGGCTGTCGCCGCATTCGCGCGACCGCATCGCAAGCTA
GGCACCAGAGGAGCAGGGCA

Downstream 100 bases:

>100_bases
TCGGTGAATGAACTAAGCAATCGAAGCGAGGGAGATCAGAGATGAGCACGGACGTTGCAGTCAGGGTCGAAGACAAACTG
TTCTACAATCGCTACCAGGT

Product: flavoprotein-ubiquinone oxidoreductase FixC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIEERFDAIVVGAGMAGNAAALTMAQRGMKVLQLERGEYSGSKNVQGAILYADMLEKLIPDFREEAPLERHLVEQRFWML
DDKSHVGLHYKSDDFNEEKPNRYTIIRAQFDKWFSSKVKEAGATVLCETTVTELAQDAYGKVIGVKTDRRDGEIHADVVV
LAEGVNGLLGTRAGLRERPKPENVALAVKEMHFLPRETIEARFNLKGDEGAVIEAAGTISRGMTGMGFIYSNKECISLGI
GCLVSDFQKTGETPYGLLERFKQHPSVAPLIEGSEVKEYSAHLIPEGGYNAIPQLCGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAEAIFQVKSRRDPMTKENLALYKKMLEESFVIKDLKKYKDMPALLHNQSQNFFLTYPQLVSKAMQNFVRVDG
TPKKEKESSMLRSFVSARSWTGLFGDAFKFARAWR

Sequences:

>Translated_435_residues
MIEERFDAIVVGAGMAGNAAALTMAQRGMKVLQLERGEYSGSKNVQGAILYADMLEKLIPDFREEAPLERHLVEQRFWML
DDKSHVGLHYKSDDFNEEKPNRYTIIRAQFDKWFSSKVKEAGATVLCETTVTELAQDAYGKVIGVKTDRRDGEIHADVVV
LAEGVNGLLGTRAGLRERPKPENVALAVKEMHFLPRETIEARFNLKGDEGAVIEAAGTISRGMTGMGFIYSNKECISLGI
GCLVSDFQKTGETPYGLLERFKQHPSVAPLIEGSEVKEYSAHLIPEGGYNAIPQLCGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAEAIFQVKSRRDPMTKENLALYKKMLEESFVIKDLKKYKDMPALLHNQSQNFFLTYPQLVSKAMQNFVRVDG
TPKKEKESSMLRSFVSARSWTGLFGDAFKFARAWR
>Mature_435_residues
MIEERFDAIVVGAGMAGNAAALTMAQRGMKVLQLERGEYSGSKNVQGAILYADMLEKLIPDFREEAPLERHLVEQRFWML
DDKSHVGLHYKSDDFNEEKPNRYTIIRAQFDKWFSSKVKEAGATVLCETTVTELAQDAYGKVIGVKTDRRDGEIHADVVV
LAEGVNGLLGTRAGLRERPKPENVALAVKEMHFLPRETIEARFNLKGDEGAVIEAAGTISRGMTGMGFIYSNKECISLGI
GCLVSDFQKTGETPYGLLERFKQHPSVAPLIEGSEVKEYSAHLIPEGGYNAIPQLCGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAEAIFQVKSRRDPMTKENLALYKKMLEESFVIKDLKKYKDMPALLHNQSQNFFLTYPQLVSKAMQNFVRVDG
TPKKEKESSMLRSFVSARSWTGLFGDAFKFARAWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=406, Percent_Identity=26.3546798029557, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI1786227, Length=415, Percent_Identity=39.0361445783133, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1787991, Length=440, Percent_Identity=38.8636363636364, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI87082155, Length=384, Percent_Identity=36.71875, Blast_Score=229, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI25144720, Length=393, Percent_Identity=24.4274809160305, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324932, Length=416, Percent_Identity=26.4423076923077, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24652256, Length=403, Percent_Identity=26.0545905707196, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 48484; Mature: 48484

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEERFDAIVVGAGMAGNAAALTMAQRGMKVLQLERGEYSGSKNVQGAILYADMLEKLIP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHH
DFREEAPLERHLVEQRFWMLDDKSHVGLHYKSDDFNEEKPNRYTIIRAQFDKWFSSKVKE
HHHHCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGATVLCETTVTELAQDAYGKVIGVKTDRRDGEIHADVVVLAEGVNGLLGTRAGLRERPK
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHCCCCCCCCCC
PENVALAVKEMHFLPRETIEARFNLKGDEGAVIEAAGTISRGMTGMGFIYSNKECISLGI
CCHHHHHHHHHHHCCHHHHHHEEECCCCCCCEEEECCHHHCCCCCCEEEECCCHHHHHHH
GCLVSDFQKTGETPYGLLERFKQHPSVAPLIEGSEVKEYSAHLIPEGGYNAIPQLCGDGW
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCC
VVVGDAAQLNNAIHREGSNLAMTSGRIAAEAIFQVKSRRDPMTKENLALYKKMLEESFVI
EEECCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPALLHNQSQNFFLTYPQLVSKAMQNFVRVDGTPKKEKESSMLRSFVSARSW
HHHHHHCCCHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
TGLFGDAFKFARAWR
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MIEERFDAIVVGAGMAGNAAALTMAQRGMKVLQLERGEYSGSKNVQGAILYADMLEKLIP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHH
DFREEAPLERHLVEQRFWMLDDKSHVGLHYKSDDFNEEKPNRYTIIRAQFDKWFSSKVKE
HHHHCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGATVLCETTVTELAQDAYGKVIGVKTDRRDGEIHADVVVLAEGVNGLLGTRAGLRERPK
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHCCCCCCCCCC
PENVALAVKEMHFLPRETIEARFNLKGDEGAVIEAAGTISRGMTGMGFIYSNKECISLGI
CCHHHHHHHHHHHCCHHHHHHEEECCCCCCCEEEECCHHHCCCCCCEEEECCCHHHHHHH
GCLVSDFQKTGETPYGLLERFKQHPSVAPLIEGSEVKEYSAHLIPEGGYNAIPQLCGDGW
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCC
VVVGDAAQLNNAIHREGSNLAMTSGRIAAEAIFQVKSRRDPMTKENLALYKKMLEESFVI
EEECCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPALLHNQSQNFFLTYPQLVSKAMQNFVRVDGTPKKEKESSMLRSFVSARSW
HHHHHHCCCHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
TGLFGDAFKFARAWR
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]