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The map label for this gene is cobU [H]

Identifier: 146341792

GI number: 146341792

Start: 5111827

End: 5112360

Strand: Direct

Name: cobU [H]

Synonym: BRADO4911

Alternate gene names: 146341792

Gene position: 5111827-5112360 (Clockwise)

Preceding gene: 146341783

Following gene: 146341793

Centisome position: 68.55

GC content: 67.98

Gene sequence:

>534_bases
ATGCCCCCTGCTCCGCCCCCCGACCTGCCGCGCCTCACCCTGGTGCTCGGCGGCGCGCGCTCGGGCAAGAGTCGCCACGC
CGAGGCGCTGATCACCGCGCAGGCGCCGCCCTGGATCTATGTTGCGACTGCGCAGGCGTTCGATGCCGAGATGACCGAGC
GCATCGCCCAACACAAGGCACGCCGCGCCGAGGGATGGCAGACGCGCGAGACGACGCAGGATCTCGCAGGTCTCATCCGC
GCATGCGCGGAGCATCGCGCGCCGATCTTGATCGATTGCCTGACGCTGTGGCTCAGCAATGTGATGCTCGCCGACAGGAA
TGTTCCAGCGGCTTGCGCGGACCTGATCGATACGCTCGGCACTGCGCGTGGCCCGATCGTCGCCGTCTCCAACGAGGTCG
GTCTCGGCATCGTGCCGGACAACGCGCTGGCACGCGCCTTTCGCGATGCCCAGGGCCGATTGAACCAGGACGTCGCAGCC
GTTGCGGATCGCGTGATCCTGATGACGGCCGGGCTGCCGCTCATCTTGAAGTGA

Upstream 100 bases:

>100_bases
GGTCGAAGACCCGCACCGTGTTCCCTAAATCTCTCCTTTCGGAGAACCGTCATCTGTTAGATACGGGTCGCGCCAAAGCC
CGTCAATCGGAATCGTTCCC

Downstream 100 bases:

>100_bases
AGAGGACGAACCGATGACAGAGAACGACGACGACGCGCGTCACAAGGCCAAGATGGAGAATCGCAAGGCGGTTCAGGATG
CCGAGGTCGCCTCGAAGACG

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MPPAPPPDLPRLTLVLGGARSGKSRHAEALITAQAPPWIYVATAQAFDAEMTERIAQHKARRAEGWQTRETTQDLAGLIR
ACAEHRAPILIDCLTLWLSNVMLADRNVPAACADLIDTLGTARGPIVAVSNEVGLGIVPDNALARAFRDAQGRLNQDVAA
VADRVILMTAGLPLILK

Sequences:

>Translated_177_residues
MPPAPPPDLPRLTLVLGGARSGKSRHAEALITAQAPPWIYVATAQAFDAEMTERIAQHKARRAEGWQTRETTQDLAGLIR
ACAEHRAPILIDCLTLWLSNVMLADRNVPAACADLIDTLGTARGPIVAVSNEVGLGIVPDNALARAFRDAQGRLNQDVAA
VADRVILMTAGLPLILK
>Mature_176_residues
PPAPPPDLPRLTLVLGGARSGKSRHAEALITAQAPPWIYVATAQAFDAEMTERIAQHKARRAEGWQTRETTQDLAGLIRA
CAEHRAPILIDCLTLWLSNVMLADRNVPAACADLIDTLGTARGPIVAVSNEVGLGIVPDNALARAFRDAQGRLNQDVAAV
ADRVILMTAGLPLILK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=39.2265193370166, Blast_Score=119, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18910; Mature: 18779

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAPPPDLPRLTLVLGGARSGKSRHAEALITAQAPPWIYVATAQAFDAEMTERIAQHKA
CCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHH
RRAEGWQTRETTQDLAGLIRACAEHRAPILIDCLTLWLSNVMLADRNVPAACADLIDTLG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
TARGPIVAVSNEVGLGIVPDNALARAFRDAQGRLNQDVAAVADRVILMTAGLPLILK
CCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure 
PPAPPPDLPRLTLVLGGARSGKSRHAEALITAQAPPWIYVATAQAFDAEMTERIAQHKA
CCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHH
RRAEGWQTRETTQDLAGLIRACAEHRAPILIDCLTLWLSNVMLADRNVPAACADLIDTLG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
TARGPIVAVSNEVGLGIVPDNALARAFRDAQGRLNQDVAAVADRVILMTAGLPLILK
CCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]