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The map label for this gene is cobK [H]

Identifier: 146341783

GI number: 146341783

Start: 5101813

End: 5102586

Strand: Direct

Name: cobK [H]

Synonym: BRADO4902

Alternate gene names: 146341783

Gene position: 5101813-5102586 (Clockwise)

Preceding gene: 146341779

Following gene: 146341792

Centisome position: 68.42

GC content: 69.51

Gene sequence:

>774_bases
ATGCGCATTCTCATACTCGGCGGTACCACCGAGGCGTCCGAGTTGGCACAGCTCCTGGCCGGCGACCGCCGGTTCGACAC
GACGCTGTCGCTCGCCGGCCGCACGTCCACGCCACGGCCGCAGCCGCTGCCGACCCGCATCGGCGGCTTTGGCGGCATCG
CCGGGCTGGAAGCGTGGCTGCGCGATCATGCTGTCGACGCCGTGATCGACGCGACCCATCCTTACGCCGACCAGATCTCG
CGGCATGCCGTTGCGGCCTGCACCGCGCTGTCTCTGCCGCTGGCCTCGATCCAACGCGCGGAATGGCATCGCCAGGCGGG
CGACAATTGGATCGAGGTCGCCAGCGCGGAGACCGCTGTCGGTGCGCTCGGGTCCGAAGCTTCGCGCGTGTTTCTCAGTC
TCGGCCGCCTCGAGCTCGCGGCCTTCGCCGCGGCGCCGCAGCATCACTACATCGCGCGCACGATCGATCCGCCCGGCGAC
ATCGCGCTGCCGCCCGACATCCGTTTCATCAGGGACCGCGGACCGTTCGATCGGGCGAAGGAGCACGCCTTCTTGGCGGA
GGAGCGCATCGCTGTCGTGGTGTCGAAGAATTCCGGCGGAGCGGCGACCTATCCGAAGATCGCGGCCGCGCGACAGCTCG
GCATTCCCGTCGTGATGATCTCGCGGCCGGAGAAGCCGCACGGCGTCGCGCTGGACGGTGCGCGAGCCGCGCTGCAGTGG
CTCGAGACGCAGCTTGCTCATCGCCCTGCTCCGGCTTCTCGGCGCAGCGTATAG

Upstream 100 bases:

>100_bases
GTAGAGAGACCGTCAACGCCGTCCTCACCGATCCCGATGATGGACAGCCAGCGCGGCGCGTTGCAGGTTGCGTTTGGACT
CACCATGGATCCAGCCCCGC

Downstream 100 bases:

>100_bases
ACGAATGGCGCCTTGCCGTCGCGCGCGATCAGGCGCGTCGCCGTCGATCCGATCAGGACCAGCGTGCGCATATCGGCCTT
GGCGGGATCGACCTCAGCCA

Product: precorrin-6A reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRILILGGTTEASELAQLLAGDRRFDTTLSLAGRTSTPRPQPLPTRIGGFGGIAGLEAWLRDHAVDAVIDATHPYADQIS
RHAVAACTALSLPLASIQRAEWHRQAGDNWIEVASAETAVGALGSEASRVFLSLGRLELAAFAAAPQHHYIARTIDPPGD
IALPPDIRFIRDRGPFDRAKEHAFLAEERIAVVVSKNSGGAATYPKIAAARQLGIPVVMISRPEKPHGVALDGARAALQW
LETQLAHRPAPASRRSV

Sequences:

>Translated_257_residues
MRILILGGTTEASELAQLLAGDRRFDTTLSLAGRTSTPRPQPLPTRIGGFGGIAGLEAWLRDHAVDAVIDATHPYADQIS
RHAVAACTALSLPLASIQRAEWHRQAGDNWIEVASAETAVGALGSEASRVFLSLGRLELAAFAAAPQHHYIARTIDPPGD
IALPPDIRFIRDRGPFDRAKEHAFLAEERIAVVVSKNSGGAATYPKIAAARQLGIPVVMISRPEKPHGVALDGARAALQW
LETQLAHRPAPASRRSV
>Mature_257_residues
MRILILGGTTEASELAQLLAGDRRFDTTLSLAGRTSTPRPQPLPTRIGGFGGIAGLEAWLRDHAVDAVIDATHPYADQIS
RHAVAACTALSLPLASIQRAEWHRQAGDNWIEVASAETAVGALGSEASRVFLSLGRLELAAFAAAPQHHYIARTIDPPGD
IALPPDIRFIRDRGPFDRAKEHAFLAEERIAVVVSKNSGGAATYPKIAAARQLGIPVVMISRPEKPHGVALDGARAALQW
LETQLAHRPAPASRRSV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27450; Mature: 27450

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILILGGTTEASELAQLLAGDRRFDTTLSLAGRTSTPRPQPLPTRIGGFGGIAGLEAWL
CEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHH
RDHAVDAVIDATHPYADQISRHAVAACTALSLPLASIQRAEWHRQAGDNWIEVASAETAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHH
GALGSEASRVFLSLGRLELAAFAAAPQHHYIARTIDPPGDIALPPDIRFIRDRGPFDRAK
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCEEECCCCCHHHHH
EHAFLAEERIAVVVSKNSGGAATYPKIAAARQLGIPVVMISRPEKPHGVALDGARAALQW
HHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHHHHH
LETQLAHRPAPASRRSV
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRILILGGTTEASELAQLLAGDRRFDTTLSLAGRTSTPRPQPLPTRIGGFGGIAGLEAWL
CEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHH
RDHAVDAVIDATHPYADQISRHAVAACTALSLPLASIQRAEWHRQAGDNWIEVASAETAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHH
GALGSEASRVFLSLGRLELAAFAAAPQHHYIARTIDPPGDIALPPDIRFIRDRGPFDRAK
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCEEECCCCCHHHHH
EHAFLAEERIAVVVSKNSGGAATYPKIAAARQLGIPVVMISRPEKPHGVALDGARAALQW
HHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHHHHH
LETQLAHRPAPASRRSV
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]