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The map label for this gene is slyA [H]

Identifier: 146341567

GI number: 146341567

Start: 4859090

End: 4859575

Strand: Direct

Name: slyA [H]

Synonym: BRADO4668

Alternate gene names: 146341567

Gene position: 4859090-4859575 (Clockwise)

Preceding gene: 146341566

Following gene: 146341568

Centisome position: 65.17

GC content: 68.52

Gene sequence:

>486_bases
ATGATGTCAGACCCGGCCAAGACTCAATCGGAGATCGGCCTGCTGATCGCCCGTGTCGCCCGGCTGTGGCGGCGCGCGGC
CGACCAGGCCCTGGCCGACCACGGCCTCTCGCAAGCCACGGCTCACCCGTTGCGGGCGCTAGCGCGGCGCGGAAGAAACG
CAAGTAGCGGCATCCGCCAGGGTGCGCTCGCCGAGGAGGTCGGAATAGAGGGGCCCTCCCTCGTCCGCCTCATCGACCTG
TTGCAGACAGAAAACCTCGTTGAGCGCCGGGAGGACCCCACCGACCGCCGGGCCAAGACGCTGCATCTGACCGCCCGAGG
CGAGGCCAAGGCCGACGAGATCGAGGCGGTGCTCCGGCGCGTGCGCGGCTTTCTGCTCAAAGACATCTCCCCCGAGGACC
TCGCCATCGCGTCCGACGTTTTGCATCGCATCGAGCAGCGCATGCTGCGCCTGCGCGAAGCCATTCCATCCGACGCTGGG
CTGTGA

Upstream 100 bases:

>100_bases
TTGGGAACCGGCTGCGGCGCAGCCGGATCCAAAACTCCCATCACAAAGATGTTCGACCCGATCGATTGTATCCTATCAAT
TTTGCTCCTATCTAAATTCC

Downstream 100 bases:

>100_bases
TGCGAAACACGACATCATTCCCGTTACGCGGGGCAGACCTCGCGTTTTCGGCCAAGACTTTCGCCGCGGCCATGCTGGCG
CTGCTGATCGCGCTGTGGAT

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MMSDPAKTQSEIGLLIARVARLWRRAADQALADHGLSQATAHPLRALARRGRNASSGIRQGALAEEVGIEGPSLVRLIDL
LQTENLVERREDPTDRRAKTLHLTARGEAKADEIEAVLRRVRGFLLKDISPEDLAIASDVLHRIEQRMLRLREAIPSDAG
L

Sequences:

>Translated_161_residues
MMSDPAKTQSEIGLLIARVARLWRRAADQALADHGLSQATAHPLRALARRGRNASSGIRQGALAEEVGIEGPSLVRLIDL
LQTENLVERREDPTDRRAKTLHLTARGEAKADEIEAVLRRVRGFLLKDISPEDLAIASDVLHRIEQRMLRLREAIPSDAG
L
>Mature_161_residues
MMSDPAKTQSEIGLLIARVARLWRRAADQALADHGLSQATAHPLRALARRGRNASSGIRQGALAEEVGIEGPSLVRLIDL
LQTENLVERREDPTDRRAKTLHLTARGEAKADEIEAVLRRVRGFLLKDISPEDLAIASDVLHRIEQRMLRLREAIPSDAG
L

Specific function: Transcription regulator that either activates or represses expression of target genes. Regulates the cpm operon, which contains the cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, an operon involved in carbapenem-like antibiotic production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=144, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17791; Mature: 17791

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSDPAKTQSEIGLLIARVARLWRRAADQALADHGLSQATAHPLRALARRGRNASSGIRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
GALAEEVGIEGPSLVRLIDLLQTENLVERREDPTDRRAKTLHLTARGEAKADEIEAVLRR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCCHHHHHHHHHH
VRGFLLKDISPEDLAIASDVLHRIEQRMLRLREAIPSDAGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMSDPAKTQSEIGLLIARVARLWRRAADQALADHGLSQATAHPLRALARRGRNASSGIRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
GALAEEVGIEGPSLVRLIDLLQTENLVERREDPTDRRAKTLHLTARGEAKADEIEAVLRR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCCHHHHHHHHHH
VRGFLLKDISPEDLAIASDVLHRIEQRMLRLREAIPSDAGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12147472; 14528314 [H]