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The map label for this gene is aaeB [H]

Identifier: 146341568

GI number: 146341568

Start: 4859575

End: 4861626

Strand: Direct

Name: aaeB [H]

Synonym: BRADO4669

Alternate gene names: 146341568

Gene position: 4859575-4861626 (Clockwise)

Preceding gene: 146341567

Following gene: 146341569

Centisome position: 65.17

GC content: 69.54

Gene sequence:

>2052_bases
ATGCGAAACACGACATCATTCCCGTTACGCGGGGCAGACCTCGCGTTTTCGGCCAAGACTTTCGCCGCGGCCATGCTGGC
GCTGCTGATCGCGCTGTGGATCGATCTGCCGCGGCCGTATTGGGCGATGGCGACCGTCTACATCACCTCGCAGCCGCTGG
CCGGCGCCACCGCCTCCAAAGCGCTCTATCGCGTGCTCGGCACGCTCGCGGGCGCCGCGGCCGCGGTCGCCATTGTGCCG
GCCTTCGTCAATTCGCCCGAGCTGCTCAGCCTCGTGATCGCGTTGTGGACCGGCATCTGCCTCTATGTCTCGCTGCTCGA
CCGCACACCGCGCAGCTATCTGTTCATGCTGGCCGGCTACACGCTGGCGCTGATCGGGTTTCCCGCCGTGGCCGATCCGG
CCGGCATTTTCGACGTCGCTGTCGCGCGCGCGCAGGAAATCACGCTCGGCATCGTCTGCGCCACGCTTGTCTCGACCATC
GTTTTGCCGCGCAGCGTCGCGCCGGCGGTGGCCGCCAAGGTGGAGCACTGGCTCGACGAGGCGCGCCGGCTGAGCCGCGA
CGTGCTGCTCGGCGGCGGCGGCGGCGTTGACGATCGCGCGCACCGGCTCCGATTGGCCGCGGAAGCGTTGGAGATCGACA
CGCTGGCCACCCATCTCGCCTTTGACCGCGGGGCCGACCATCATGCCGTCGAGGGGCTGCGATCGCTGCGGCTGCACATG
CAGCTGCTGTTGCCGCTGCTCGGCTCGATCCACGACCGGCTTGCCGCGCTCGACGGGCATGTTGATCGCGAGCTGAGCGA
TCTGCTGCAACGTCTCGCCGGTTGGATCGTCGCGGGCGACGATCGTGAGCCCGCAAGTCGCCTGCGCGCGGTGATCGATG
CGCTGCGCCCGTCTCTGGAGGGTCGCTCCTCCTGGGACCGGATCATGATCGCGAGCCTGCTGATCCGGCTGCGCGAGCTG
GTCGACATTGCCGAGGACTGTCGCGCGCTGAATGCGGCGATCGCGGCGGGCGAGGACACCGCCAAGGTGCCTCTCGCCTT
CCGCAGCGAGCAGGGCATCGCGCCGGCGCGGCATCGCGACCACGCGCTGGCGCTGTGGTCGGCGGCCGGCGTCGTCATCG
CCATTCTCGTCTGCTGCGCGTTCTGGATCGCGACCGGCTGGGCGGACGGCGCCTCGGCGCCGATGATGGCGGCCGTCGCC
TGCTCGTTCTTCGCGTCGCAGGACGACCCCGCTCCCAGCATCGTACGGTTCGCGGCGTGGTCGCTGGTCGCCATCGTCAT
CGACGCGGTCTACCTGTTCGCCATCATCCCGGCGATCTCAGACGTCGAGCTGCTGATCGCCGCGCTGGCGCCGGCTTTCC
TGCTATTCGGCGTGCTGATCGCGCGTCCCCAGACGATGCCGATCGGCATGGCGCTCGGCGCCAATGGCGCCACGCTGCTG
GCGTTGCAGTCGACCTACAGCGCGGATTTCCAGAGCTACGCCAATTCGGCGATCGCCTTCATGGTCGGCATGGTCGCGGC
CGTGGTGCTCACCCGCCTCGTCCGCTCTGTCCGAGCCGAGTGGATCGCGCAGCGGCTGCTGCGGACAAGCTGGGAGACCT
TGGCGACAACCGCCGAGCGCCGCGGCCATCATGACCGCGCCGCCTTCGTCGGCCTGATGCTCGACCGCCTGGGATTGCTG
GCGCAGCGCTTTGCCGCCATCCCCGAGGACGACCGTCGCGAGCTCGATAATCTCAACCAGCTGCGCGTCGGCCTCAACAT
CATCGACCTCCGCCGCGCCCGTCACGGGCTCACGGCGGCGACGCTCGGCGCCATCGACACGATGCTGGATCGTCTCGCCG
CCGCCTGCAGGGGCCGCGGCCTCGGCACCGGCATGATGCCGGCCGATCTGCTGGCCGCGATCGACGTGGCGCTGCTGAAG
ACGCTCGACGAGCCAGCCGCGCCGGCCAAGGAGGACGCGCTGATCGGCCTCGTCGGCATCCGCACCGGGCTATTCCCGGA
CGCGCCGGCCTATCACGCCGACGCGACCGGTCTTCGGAGCCTCGTGGCATGA

Upstream 100 bases:

>100_bases
TCTCCCCCGAGGACCTCGCCATCGCGTCCGACGTTTTGCATCGCATCGAGCAGCGCATGCTGCGCCTGCGCGAAGCCATT
CCATCCGACGCTGGGCTGTG

Downstream 100 bases:

>100_bases
GACACGACATCGACATCGCCGGCGTACTGGTGCCATCGCTGCTGCTGTGGCTGGTCGTGGCCTATGCCTGCGTCGCGCTG
CTGCGCGCCCTCCTCCGCCG

Product: putative efflux transporter permease fusaric acid resistance pump

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MRNTTSFPLRGADLAFSAKTFAAAMLALLIALWIDLPRPYWAMATVYITSQPLAGATASKALYRVLGTLAGAAAAVAIVP
AFVNSPELLSLVIALWTGICLYVSLLDRTPRSYLFMLAGYTLALIGFPAVADPAGIFDVAVARAQEITLGIVCATLVSTI
VLPRSVAPAVAAKVEHWLDEARRLSRDVLLGGGGGVDDRAHRLRLAAEALEIDTLATHLAFDRGADHHAVEGLRSLRLHM
QLLLPLLGSIHDRLAALDGHVDRELSDLLQRLAGWIVAGDDREPASRLRAVIDALRPSLEGRSSWDRIMIASLLIRLREL
VDIAEDCRALNAAIAAGEDTAKVPLAFRSEQGIAPARHRDHALALWSAAGVVIAILVCCAFWIATGWADGASAPMMAAVA
CSFFASQDDPAPSIVRFAAWSLVAIVIDAVYLFAIIPAISDVELLIAALAPAFLLFGVLIARPQTMPIGMALGANGATLL
ALQSTYSADFQSYANSAIAFMVGMVAAVVLTRLVRSVRAEWIAQRLLRTSWETLATTAERRGHHDRAAFVGLMLDRLGLL
AQRFAAIPEDDRRELDNLNQLRVGLNIIDLRRARHGLTAATLGAIDTMLDRLAAACRGRGLGTGMMPADLLAAIDVALLK
TLDEPAAPAKEDALIGLVGIRTGLFPDAPAYHADATGLRSLVA

Sequences:

>Translated_683_residues
MRNTTSFPLRGADLAFSAKTFAAAMLALLIALWIDLPRPYWAMATVYITSQPLAGATASKALYRVLGTLAGAAAAVAIVP
AFVNSPELLSLVIALWTGICLYVSLLDRTPRSYLFMLAGYTLALIGFPAVADPAGIFDVAVARAQEITLGIVCATLVSTI
VLPRSVAPAVAAKVEHWLDEARRLSRDVLLGGGGGVDDRAHRLRLAAEALEIDTLATHLAFDRGADHHAVEGLRSLRLHM
QLLLPLLGSIHDRLAALDGHVDRELSDLLQRLAGWIVAGDDREPASRLRAVIDALRPSLEGRSSWDRIMIASLLIRLREL
VDIAEDCRALNAAIAAGEDTAKVPLAFRSEQGIAPARHRDHALALWSAAGVVIAILVCCAFWIATGWADGASAPMMAAVA
CSFFASQDDPAPSIVRFAAWSLVAIVIDAVYLFAIIPAISDVELLIAALAPAFLLFGVLIARPQTMPIGMALGANGATLL
ALQSTYSADFQSYANSAIAFMVGMVAAVVLTRLVRSVRAEWIAQRLLRTSWETLATTAERRGHHDRAAFVGLMLDRLGLL
AQRFAAIPEDDRRELDNLNQLRVGLNIIDLRRARHGLTAATLGAIDTMLDRLAAACRGRGLGTGMMPADLLAAIDVALLK
TLDEPAAPAKEDALIGLVGIRTGLFPDAPAYHADATGLRSLVA
>Mature_683_residues
MRNTTSFPLRGADLAFSAKTFAAAMLALLIALWIDLPRPYWAMATVYITSQPLAGATASKALYRVLGTLAGAAAAVAIVP
AFVNSPELLSLVIALWTGICLYVSLLDRTPRSYLFMLAGYTLALIGFPAVADPAGIFDVAVARAQEITLGIVCATLVSTI
VLPRSVAPAVAAKVEHWLDEARRLSRDVLLGGGGGVDDRAHRLRLAAEALEIDTLATHLAFDRGADHHAVEGLRSLRLHM
QLLLPLLGSIHDRLAALDGHVDRELSDLLQRLAGWIVAGDDREPASRLRAVIDALRPSLEGRSSWDRIMIASLLIRLREL
VDIAEDCRALNAAIAAGEDTAKVPLAFRSEQGIAPARHRDHALALWSAAGVVIAILVCCAFWIATGWADGASAPMMAAVA
CSFFASQDDPAPSIVRFAAWSLVAIVIDAVYLFAIIPAISDVELLIAALAPAFLLFGVLIARPQTMPIGMALGANGATLL
ALQSTYSADFQSYANSAIAFMVGMVAAVVLTRLVRSVRAEWIAQRLLRTSWETLATTAERRGHHDRAAFVGLMLDRLGLL
AQRFAAIPEDDRRELDNLNQLRVGLNIIDLRRARHGLTAATLGAIDTMLDRLAAACRGRGLGTGMMPADLLAAIDVALLK
TLDEPAAPAKEDALIGLVGIRTGLFPDAPAYHADATGLRSLVA

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=543, Percent_Identity=25.2302025782689, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787933, Length=454, Percent_Identity=26.431718061674, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 72794; Mature: 72794

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTTSFPLRGADLAFSAKTFAAAMLALLIALWIDLPRPYWAMATVYITSQPLAGATASK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCCCHHHH
ALYRVLGTLAGAAAAVAIVPAFVNSPELLSLVIALWTGICLYVSLLDRTPRSYLFMLAGY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLALIGFPAVADPAGIFDVAVARAQEITLGIVCATLVSTIVLPRSVAPAVAAKVEHWLDE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARRLSRDVLLGGGGGVDDRAHRLRLAAEALEIDTLATHLAFDRGADHHAVEGLRSLRLHM
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QLLLPLLGSIHDRLAALDGHVDRELSDLLQRLAGWIVAGDDREPASRLRAVIDALRPSLE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCC
GRSSWDRIMIASLLIRLRELVDIAEDCRALNAAIAAGEDTAKVPLAFRSEQGIAPARHRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCC
HALALWSAAGVVIAILVCCAFWIATGWADGASAPMMAAVACSFFASQDDPAPSIVRFAAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
SLVAIVIDAVYLFAIIPAISDVELLIAALAPAFLLFGVLIARPQTMPIGMALGANGATLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
ALQSTYSADFQSYANSAIAFMVGMVAAVVLTRLVRSVRAEWIAQRLLRTSWETLATTAER
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGHHDRAAFVGLMLDRLGLLAQRFAAIPEDDRRELDNLNQLRVGLNIIDLRRARHGLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHCCHHHHHHHHHCCCHHH
TLGAIDTMLDRLAAACRGRGLGTGMMPADLLAAIDVALLKTLDEPAAPAKEDALIGLVGI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHH
RTGLFPDAPAYHADATGLRSLVA
HHCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MRNTTSFPLRGADLAFSAKTFAAAMLALLIALWIDLPRPYWAMATVYITSQPLAGATASK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCCCHHHH
ALYRVLGTLAGAAAAVAIVPAFVNSPELLSLVIALWTGICLYVSLLDRTPRSYLFMLAGY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLALIGFPAVADPAGIFDVAVARAQEITLGIVCATLVSTIVLPRSVAPAVAAKVEHWLDE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARRLSRDVLLGGGGGVDDRAHRLRLAAEALEIDTLATHLAFDRGADHHAVEGLRSLRLHM
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QLLLPLLGSIHDRLAALDGHVDRELSDLLQRLAGWIVAGDDREPASRLRAVIDALRPSLE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCC
GRSSWDRIMIASLLIRLRELVDIAEDCRALNAAIAAGEDTAKVPLAFRSEQGIAPARHRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCC
HALALWSAAGVVIAILVCCAFWIATGWADGASAPMMAAVACSFFASQDDPAPSIVRFAAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
SLVAIVIDAVYLFAIIPAISDVELLIAALAPAFLLFGVLIARPQTMPIGMALGANGATLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
ALQSTYSADFQSYANSAIAFMVGMVAAVVLTRLVRSVRAEWIAQRLLRTSWETLATTAER
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGHHDRAAFVGLMLDRLGLLAQRFAAIPEDDRRELDNLNQLRVGLNIIDLRRARHGLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHCCHHHHHHHHHCCCHHH
TLGAIDTMLDRLAAACRGRGLGTGMMPADLLAAIDVALLKTLDEPAAPAKEDALIGLVGI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHH
RTGLFPDAPAYHADATGLRSLVA
HHCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA