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The map label for this gene is yfeW [C]

Identifier: 146341540

GI number: 146341540

Start: 4829364

End: 4830554

Strand: Direct

Name: yfeW [C]

Synonym: BRADO4638

Alternate gene names: 146341540

Gene position: 4829364-4830554 (Clockwise)

Preceding gene: 146341539

Following gene: 146341548

Centisome position: 64.77

GC content: 65.83

Gene sequence:

>1191_bases
ATGTTGGTCGCAGGCTGTTGCGGGGGGCAGAACGACATGCAGTTGACGCGTCGCCAGATCATGACCGCCACGGTCGGAGC
CGTGCTCGGCGCCCATGCCGGCGCGGTCGGCGCGCAGGTCGAGCCGAAGCCGGCGCGCGTGGGTCCGCCCTCGCCTCCCG
AACGCGCAGAGATCGCGGCGCTCGGCCGGGCCTTCATGGACACCTATGGCGTGCCCGCGCTGTCGTTCGCGGTCGGCTAT
GCCGGCGAGATCGTCCACCAGGATGCGTGGGGATTTGCCGATCTGCAGGGACAGGAGGCCGTGACCCCGCAGCATCTGTT
CCGCATCGCCAGCGTCAGCAAGCCGATCACCTCGATCGCCCTGCACCGGCTGATCGAGCAAGGCAGGGTTCGCCTGGGCG
ATCGCGTGTTCGGCCCCGGCGCCGTGCTCGGCACCGACTACTTGGCTCCGCCGTACAACCCAGGCGTCGACCAGATCACG
ATCGAGCACCTGCTCACGCATACCTGCGGCGGCTGGAGCAACGACAATCGCGATCCGATGTTCGCGTTTCCGATGCGGAG
CCAATCCGAACTGATCAACTGGACCCTCACCCATCGTCCGCTCGACCATCCGCCGGGCGAGGCCTATTCCTATTCGAATT
ACGGCTATTGCTTGCTCGGACGCGTCATCGAGAAGCTCACGGGCCGTGCCTATGCCGATCACGTCCGTGCCGAGGTGCTC
GGCCGCTGTGGCGTGACCGACATGACCATCGGGGGCAACCGGCGCGATCAGCGCCAGCCGCGCGAGGTCGAGTATCTCAG
CGCGGACGAGAATGCCTACGGCATGAACGTCACACGGATGGATTCGCACGGCGGCTGGATCGCTCGCCCAGCCGATCTCG
TGCAGTTGTTCATGCATGTCGACGGCTTCACCCGGCCCGCCAATATCCTGCGCGGCGACACCATCAAGACCATGACCACC
GGCTCGCGCGCCAACAAGGACTACGCCAAGGGCTGGAGCGTGAACACGTTCGACAATTGGTGGCACACCGGCAGCCTGCC
TGGAACGACCACCATCGCCGTGCGCACCCATAGCGGCTTCTGCTGGGCCGCCTTCACCAACACGCGCCGCCGCGGAAGCA
AGATGGATGGCGATCTCGATCAGCTGTGCTGGAGCATGGTGCGCAAGGTCGATGGCTGGAAGTTCGCGTAG

Upstream 100 bases:

>100_bases
CTTTGCCCACCCTACAACTCCGTCGCAGCGGCGCCCGGGAGCTCGCGTGCGGATCGCGCAGCGGCGATGGATTGAACGAT
CGCGATCGCGGTAGCGACGT

Downstream 100 bases:

>100_bases
CGGGCTCACGGCCATCGCCATCAGATCCAGCGCCGCACCTCGCGCTGATATGTCTCGTAGGCCGCACCGAACTTGGCGGT
CATGACGCGCTCCTCGGGTA

Product: putative beta-lactamase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLVAGCCGGQNDMQLTRRQIMTATVGAVLGAHAGAVGAQVEPKPARVGPPSPPERAEIAALGRAFMDTYGVPALSFAVGY
AGEIVHQDAWGFADLQGQEAVTPQHLFRIASVSKPITSIALHRLIEQGRVRLGDRVFGPGAVLGTDYLAPPYNPGVDQIT
IEHLLTHTCGGWSNDNRDPMFAFPMRSQSELINWTLTHRPLDHPPGEAYSYSNYGYCLLGRVIEKLTGRAYADHVRAEVL
GRCGVTDMTIGGNRRDQRQPREVEYLSADENAYGMNVTRMDSHGGWIARPADLVQLFMHVDGFTRPANILRGDTIKTMTT
GSRANKDYAKGWSVNTFDNWWHTGSLPGTTTIAVRTHSGFCWAAFTNTRRRGSKMDGDLDQLCWSMVRKVDGWKFA

Sequences:

>Translated_396_residues
MLVAGCCGGQNDMQLTRRQIMTATVGAVLGAHAGAVGAQVEPKPARVGPPSPPERAEIAALGRAFMDTYGVPALSFAVGY
AGEIVHQDAWGFADLQGQEAVTPQHLFRIASVSKPITSIALHRLIEQGRVRLGDRVFGPGAVLGTDYLAPPYNPGVDQIT
IEHLLTHTCGGWSNDNRDPMFAFPMRSQSELINWTLTHRPLDHPPGEAYSYSNYGYCLLGRVIEKLTGRAYADHVRAEVL
GRCGVTDMTIGGNRRDQRQPREVEYLSADENAYGMNVTRMDSHGGWIARPADLVQLFMHVDGFTRPANILRGDTIKTMTT
GSRANKDYAKGWSVNTFDNWWHTGSLPGTTTIAVRTHSGFCWAAFTNTRRRGSKMDGDLDQLCWSMVRKVDGWKFA
>Mature_396_residues
MLVAGCCGGQNDMQLTRRQIMTATVGAVLGAHAGAVGAQVEPKPARVGPPSPPERAEIAALGRAFMDTYGVPALSFAVGY
AGEIVHQDAWGFADLQGQEAVTPQHLFRIASVSKPITSIALHRLIEQGRVRLGDRVFGPGAVLGTDYLAPPYNPGVDQIT
IEHLLTHTCGGWSNDNRDPMFAFPMRSQSELINWTLTHRPLDHPPGEAYSYSNYGYCLLGRVIEKLTGRAYADHVRAEVL
GRCGVTDMTIGGNRRDQRQPREVEYLSADENAYGMNVTRMDSHGGWIARPADLVQLFMHVDGFTRPANILRGDTIKTMTT
GSRANKDYAKGWSVNTFDNWWHTGSLPGTTTIAVRTHSGFCWAAFTNTRRRGSKMDGDLDQLCWSMVRKVDGWKFA

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550934, Length=343, Percent_Identity=34.6938775510204, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17565630, Length=332, Percent_Identity=31.0240963855422, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115533026, Length=346, Percent_Identity=23.6994219653179, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43493; Mature: 43493

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAGCCGGQNDMQLTRRQIMTATVGAVLGAHAGAVGAQVEPKPARVGPPSPPERAEIAA
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LGRAFMDTYGVPALSFAVGYAGEIVHQDAWGFADLQGQEAVTPQHLFRIASVSKPITSIA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
LHRLIEQGRVRLGDRVFGPGAVLGTDYLAPPYNPGVDQITIEHLLTHTCGGWSNDNRDPM
HHHHHHHCCCEECCEECCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCE
FAFPMRSQSELINWTLTHRPLDHPPGEAYSYSNYGYCLLGRVIEKLTGRAYADHVRAEVL
EEECCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
GRCGVTDMTIGGNRRDQRQPREVEYLSADENAYGMNVTRMDSHGGWIARPADLVQLFMHV
HHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCEEECHHHHHHHHHHH
DGFTRPANILRGDTIKTMTTGSRANKDYAKGWSVNTFDNWWHTGSLPGTTTIAVRTHSGF
CCCCCCHHHHCCCCEEEEECCCCCCCHHHCCCCCCCCCCCEECCCCCCCEEEEEEECCCE
CWAAFTNTRRRGSKMDGDLDQLCWSMVRKVDGWKFA
EEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLVAGCCGGQNDMQLTRRQIMTATVGAVLGAHAGAVGAQVEPKPARVGPPSPPERAEIAA
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LGRAFMDTYGVPALSFAVGYAGEIVHQDAWGFADLQGQEAVTPQHLFRIASVSKPITSIA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
LHRLIEQGRVRLGDRVFGPGAVLGTDYLAPPYNPGVDQITIEHLLTHTCGGWSNDNRDPM
HHHHHHHCCCEECCEECCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCE
FAFPMRSQSELINWTLTHRPLDHPPGEAYSYSNYGYCLLGRVIEKLTGRAYADHVRAEVL
EEECCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
GRCGVTDMTIGGNRRDQRQPREVEYLSADENAYGMNVTRMDSHGGWIARPADLVQLFMHV
HHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCEEECHHHHHHHHHHH
DGFTRPANILRGDTIKTMTTGSRANKDYAKGWSVNTFDNWWHTGSLPGTTTIAVRTHSGF
CCCCCCHHHHCCCCEEEEECCCCCCCHHHCCCCCCCCCCCEECCCCCCCEEEEEEECCCE
CWAAFTNTRRRGSKMDGDLDQLCWSMVRKVDGWKFA
EEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]