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The map label for this gene is panC [H]

Identifier: 146341462

GI number: 146341462

Start: 4753539

End: 4754390

Strand: Direct

Name: panC [H]

Synonym: BRADO4554

Alternate gene names: 146341462

Gene position: 4753539-4754390 (Clockwise)

Preceding gene: 146341457

Following gene: 146341472

Centisome position: 63.75

GC content: 65.61

Gene sequence:

>852_bases
ATGTCACGACATCCGCGTATCGCCCGCACCATTCCTACTCTGCGCCGCGAGCTCGACAGCTTGCGCGCGAGGAAGGCCAG
CATCGCTCTCGTGCCGACCATGGGTGCGCTGCATGACGGCCACATCTCGCTCGTTCGGCTGGCGAAGCGCCGCGCCGACA
AGGTCGTTGTCTCGATCTTCGTCAACCCGACTCAGTTCGCGCCGACAGAGGATTTCGGCTCTTACCCGCGCACCTGGAAT
GAGGATGTTGCCAAGCTCAGCGCCGAGCGCGTCGATCTGATCTGGCACCCCGATGCCAAGGCGATGTATCCGGACGGCTT
TGCGACGCGGATCGTACCGGAAGGTCCGGCGCTCGCCGGGCTGGAGGATCGCTTCCGCCCGCACTTCTTCGGCGGCGTCG
CCACGGTCGTGGCCAAGCTGTTCACGCAATGCCGGCCCGACGTCGCGATCTTCGGCGAGAAGGACTATCAGCAGCTGCGT
GTCGTCACCCGGATGGCGCGCGACCTCGATCTCGGCGTGCGCGTCGTGGGCTGCCGTACGGTGCGCGAACGCGACGGTCT
CGCGATGTCCTCGCGAAATGTCTATCTCAGTGCAGACGAGCGCCACGTCGCACCCACGCTCCATCGCGTGCTGAAACAGA
TCGCAACGCGGTTGCGCGCCGGTGACACTATGCACGACGCGGTTCATGACGGCGCCGTGACGATCACCGAGGCGGGCTTC
ACCTTGGACTATCTCGAAGTCCGCCATGCCGAGACGCTGGCGCCACTGGCCGCAGGCGCGTCCGGACCAAAGCGGATCCT
GGTTGCGGCCAAGCTCGGAACCACGCGCCTGATCGACAACATCGCGGCGTGA

Upstream 100 bases:

>100_bases
AGTAGGCTGATCGGTTTGCATCGCCCTTGTGAAAGGCGCCCCGCCGAGCGTCAAGGCCGAACACAAGACCTGCGATTTTT
CGCTGCGAGATCGAGCAAAA

Downstream 100 bases:

>100_bases
GCTTCGCAAGATATCGCCCGACCGGTGCCGATGACTGCGCCCTCCCCTTGCGGGCCCCGCAAGGGAGAGAGCGCGGCAAC
TGGCATCGCGGAAGAGATGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSRHPRIARTIPTLRRELDSLRARKASIALVPTMGALHDGHISLVRLAKRRADKVVVSIFVNPTQFAPTEDFGSYPRTWN
EDVAKLSAERVDLIWHPDAKAMYPDGFATRIVPEGPALAGLEDRFRPHFFGGVATVVAKLFTQCRPDVAIFGEKDYQQLR
VVTRMARDLDLGVRVVGCRTVRERDGLAMSSRNVYLSADERHVAPTLHRVLKQIATRLRAGDTMHDAVHDGAVTITEAGF
TLDYLEVRHAETLAPLAAGASGPKRILVAAKLGTTRLIDNIAA

Sequences:

>Translated_283_residues
MSRHPRIARTIPTLRRELDSLRARKASIALVPTMGALHDGHISLVRLAKRRADKVVVSIFVNPTQFAPTEDFGSYPRTWN
EDVAKLSAERVDLIWHPDAKAMYPDGFATRIVPEGPALAGLEDRFRPHFFGGVATVVAKLFTQCRPDVAIFGEKDYQQLR
VVTRMARDLDLGVRVVGCRTVRERDGLAMSSRNVYLSADERHVAPTLHRVLKQIATRLRAGDTMHDAVHDGAVTITEAGF
TLDYLEVRHAETLAPLAAGASGPKRILVAAKLGTTRLIDNIAA
>Mature_282_residues
SRHPRIARTIPTLRRELDSLRARKASIALVPTMGALHDGHISLVRLAKRRADKVVVSIFVNPTQFAPTEDFGSYPRTWNE
DVAKLSAERVDLIWHPDAKAMYPDGFATRIVPEGPALAGLEDRFRPHFFGGVATVVAKLFTQCRPDVAIFGEKDYQQLRV
VTRMARDLDLGVRVVGCRTVRERDGLAMSSRNVYLSADERHVAPTLHRVLKQIATRLRAGDTMHDAVHDGAVTITEAGFT
LDYLEVRHAETLAPLAAGASGPKRILVAAKLGTTRLIDNIAA

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=276, Percent_Identity=46.7391304347826, Blast_Score=243, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6322046, Length=294, Percent_Identity=37.0748299319728, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31241; Mature: 31110

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHPRIARTIPTLRRELDSLRARKASIALVPTMGALHDGHISLVRLAKRRADKVVVSIF
CCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEE
VNPTQFAPTEDFGSYPRTWNEDVAKLSAERVDLIWHPDAKAMYPDGFATRIVPEGPALAG
ECCCCCCCCHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCCCCCCCC
LEDRFRPHFFGGVATVVAKLFTQCRPDVAIFGEKDYQQLRVVTRMARDLDLGVRVVGCRT
HHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEH
VRERDGLAMSSRNVYLSADERHVAPTLHRVLKQIATRLRAGDTMHDAVHDGAVTITEAGF
HHHCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCC
TLDYLEVRHAETLAPLAAGASGPKRILVAAKLGTTRLIDNIAA
EEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
SRHPRIARTIPTLRRELDSLRARKASIALVPTMGALHDGHISLVRLAKRRADKVVVSIF
CCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEE
VNPTQFAPTEDFGSYPRTWNEDVAKLSAERVDLIWHPDAKAMYPDGFATRIVPEGPALAG
ECCCCCCCCHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCCCCCCCC
LEDRFRPHFFGGVATVVAKLFTQCRPDVAIFGEKDYQQLRVVTRMARDLDLGVRVVGCRT
HHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEH
VRERDGLAMSSRNVYLSADERHVAPTLHRVLKQIATRLRAGDTMHDAVHDGAVTITEAGF
HHHCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCC
TLDYLEVRHAETLAPLAAGASGPKRILVAAKLGTTRLIDNIAA
EEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA