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The map label for this gene is 146341369

Identifier: 146341369

GI number: 146341369

Start: 4655558

End: 4657147

Strand: Reverse

Name: 146341369

Synonym: BRADO4455

Alternate gene names: NA

Gene position: 4657147-4655558 (Counterclockwise)

Preceding gene: 146341370

Following gene: 146341368

Centisome position: 62.46

GC content: 68.3

Gene sequence:

>1590_bases
CTGCAAGCCGACCTCGTCATCGCCGGCGGCGGCCTCGCCGGCATCGTCACCGCGCTCGAGGCTTTGCGCGCCGGCAACTC
CGTCGTAATCGTCGATCGCGATACGCCGGAGCGGTTCGGTGGACTGGCGCTGTGGGCCTTCGGAGGCATGGCGCTGGTCG
GCACGCCCTTGCAGGCGCGGATGAAGATCCCGGACACGCCGGAGATCGCGCTGCGCGACTGGATCCGGTTCGGCGAGCTC
GACGAGCGCGAGCACTGGCCGTTGCAGTGGGCGCGCTATTACGTCGAGCATTCGCGGAGCGAGATCTACGACTGGCTGTC
GTCGCACGGCGTGACCTTTATGCCCGCCGTGAACTGGGTCGAGCGCGGCCTCGTGGGCGACGGCAACGCGCTGCCGCGCT
ATCACATCGTCTGGGGCACCTCGCAGCGGCTGACGCGCGTGATGATCGCCGCGATGCGCGCCGCCGATCGCGGCGGCAAG
CTGACGGTGCTGCATCGTCATCGCGTGGTCGGCCTCGATCGGGCGGGCGGAGCTATGGCGGGCGTCATCGCCGTCAATGA
GGATAGCGGTGCCGAGATCCGCATCGCTGCGCCGCTGACGGTGCTCGCCATGGGCGGCATCAATGGCGGCCATGCGGAGG
CGCGCGCCAACTGGGTGAAGGGACGGCCGATGCCGTCCGCCATGCTCAACGGCGCGCACCCGTTCGCCGACGGCAAGCTG
CATCATCACGCGGCCGAGACCATCGGCGCGCAGATCACCCATGCCGGCGAAATGTGGAACTACGCCGCCGGAATTCCGCA
TCCGTTTCCGCATTTCGACGGTCACGGCCTGTCGCTGGTGCCGTGCAAATCGGCGCTGTGGCTCGACCATCGCGGCGAGC
GCATCGGCCCGCAGCCGCTGGTCACCGGCTTCGACACCTACGATCTGTGCCAGCGCGTCGCCGCGCAGGAGAAGCCGTAT
ACGTGGCACCTGTTGAACTGGCGGATTGCCGCCAAGGAGTTCGCGATCTCGGGCGCCGAGCACAATGCGCGCATCCGCGA
GCGGCAGATGCCGATGTTCCTCAAGGAGACGTTGCTCGGCAATCACCGCCTGGTCCGGCAGATGCAGCGCGAGAGCCGGC
ATTTCCTGGTCGACGAGACGCTGGCGGGCCTTGCCGCCAAGATGAACGCGTTCACCGGCACCGACGACATCAAGCCCGAG
GTGCTGCAGGCGACCGCCGATGCCTTCGATGCGAACTTCGAGAACGGCGACAAGCTCTTCAACGACGACCAGCTGCGCCG
CATCCTGCACGCGCGGCAATGGGGACCCGACAAGCTGCGCACCTGCAAGCCGGCGCCGCTGCAGATGCGCGGGGCCGGGC
CGTTCATCGCGATCCACATGCAGCTGATCACCCGCAAGAGCCTCGGCGGCCTGAAGACCGATCTGCACAGCCGGCTGCTC
GACGCCGCGGGCAGCCCGATCAGCGGCCTCTACGCCGTCGGCGAAGCCGCGGGCTTCGGGGGCGGTGGCGCCTCGGGCAA
GCGCTCGCTGGAGGGAACATTTCTGCCCGGCTGCATCCTCACGGCAAAGGCAGCGGTAAAGGCGATGTGA

Upstream 100 bases:

>100_bases
CTGAAGCTGCTGCCGCATCTGCTGGGATCGCTCGACCGCGTGCCGCTGCCGGTGGCGCGCATGCTCAAGCGCAAGATTGC
GCCGTGACATGAGCGCGCCG

Downstream 100 bases:

>100_bases
GGAGCGCGAGGGCAACGAGCGATGTTCCTCAAGACAGGCGCGTCGCTTAGTGAGGGGCAGGATCTCTCCGCACGTCATTC
CGGGGCGCACCGTAATGACG

Product: putative fumarate reductase flavoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MQADLVIAGGGLAGIVTALEALRAGNSVVIVDRDTPERFGGLALWAFGGMALVGTPLQARMKIPDTPEIALRDWIRFGEL
DEREHWPLQWARYYVEHSRSEIYDWLSSHGVTFMPAVNWVERGLVGDGNALPRYHIVWGTSQRLTRVMIAAMRAADRGGK
LTVLHRHRVVGLDRAGGAMAGVIAVNEDSGAEIRIAAPLTVLAMGGINGGHAEARANWVKGRPMPSAMLNGAHPFADGKL
HHHAAETIGAQITHAGEMWNYAAGIPHPFPHFDGHGLSLVPCKSALWLDHRGERIGPQPLVTGFDTYDLCQRVAAQEKPY
TWHLLNWRIAAKEFAISGAEHNARIRERQMPMFLKETLLGNHRLVRQMQRESRHFLVDETLAGLAAKMNAFTGTDDIKPE
VLQATADAFDANFENGDKLFNDDQLRRILHARQWGPDKLRTCKPAPLQMRGAGPFIAIHMQLITRKSLGGLKTDLHSRLL
DAAGSPISGLYAVGEAAGFGGGGASGKRSLEGTFLPGCILTAKAAVKAM

Sequences:

>Translated_529_residues
MQADLVIAGGGLAGIVTALEALRAGNSVVIVDRDTPERFGGLALWAFGGMALVGTPLQARMKIPDTPEIALRDWIRFGEL
DEREHWPLQWARYYVEHSRSEIYDWLSSHGVTFMPAVNWVERGLVGDGNALPRYHIVWGTSQRLTRVMIAAMRAADRGGK
LTVLHRHRVVGLDRAGGAMAGVIAVNEDSGAEIRIAAPLTVLAMGGINGGHAEARANWVKGRPMPSAMLNGAHPFADGKL
HHHAAETIGAQITHAGEMWNYAAGIPHPFPHFDGHGLSLVPCKSALWLDHRGERIGPQPLVTGFDTYDLCQRVAAQEKPY
TWHLLNWRIAAKEFAISGAEHNARIRERQMPMFLKETLLGNHRLVRQMQRESRHFLVDETLAGLAAKMNAFTGTDDIKPE
VLQATADAFDANFENGDKLFNDDQLRRILHARQWGPDKLRTCKPAPLQMRGAGPFIAIHMQLITRKSLGGLKTDLHSRLL
DAAGSPISGLYAVGEAAGFGGGGASGKRSLEGTFLPGCILTAKAAVKAM
>Mature_529_residues
MQADLVIAGGGLAGIVTALEALRAGNSVVIVDRDTPERFGGLALWAFGGMALVGTPLQARMKIPDTPEIALRDWIRFGEL
DEREHWPLQWARYYVEHSRSEIYDWLSSHGVTFMPAVNWVERGLVGDGNALPRYHIVWGTSQRLTRVMIAAMRAADRGGK
LTVLHRHRVVGLDRAGGAMAGVIAVNEDSGAEIRIAAPLTVLAMGGINGGHAEARANWVKGRPMPSAMLNGAHPFADGKL
HHHAAETIGAQITHAGEMWNYAAGIPHPFPHFDGHGLSLVPCKSALWLDHRGERIGPQPLVTGFDTYDLCQRVAAQEKPY
TWHLLNWRIAAKEFAISGAEHNARIRERQMPMFLKETLLGNHRLVRQMQRESRHFLVDETLAGLAAKMNAFTGTDDIKPE
VLQATADAFDANFENGDKLFNDDQLRRILHARQWGPDKLRTCKPAPLQMRGAGPFIAIHMQLITRKSLGGLKTDLHSRLL
DAAGSPISGLYAVGEAAGFGGGGASGKRSLEGTFLPGCILTAKAAVKAM

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 57650; Mature: 57650

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADLVIAGGGLAGIVTALEALRAGNSVVIVDRDTPERFGGLALWAFGGMALVGTPLQAR
CCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCEEEEHHCCEEEECCCHHHE
MKIPDTPEIALRDWIRFGELDEREHWPLQWARYYVEHSRSEIYDWLSSHGVTFMPAVNWV
ECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHH
ERGLVGDGNALPRYHIVWGTSQRLTRVMIAAMRAADRGGKLTVLHRHRVVGLDRAGGAMA
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCEE
GVIAVNEDSGAEIRIAAPLTVLAMGGINGGHAEARANWVKGRPMPSAMLNGAHPFADGKL
EEEEEECCCCCEEEEECCEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCH
HHHAAETIGAQITHAGEMWNYAAGIPHPFPHFDGHGLSLVPCKSALWLDHRGERIGPQPL
HHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCC
VTGFDTYDLCQRVAAQEKPYTWHLLNWRIAAKEFAISGAEHNARIRERQMPMFLKETLLG
EECCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHEECCCCCCCHHHHHHCCHHHHHHHHC
NHRLVRQMQRESRHFLVDETLAGLAAKMNAFTGTDDIKPEVLQATADAFDANFENGDKLF
CHHHHHHHHHHHCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
NDDQLRRILHARQWGPDKLRTCKPAPLQMRGAGPFIAIHMQLITRKSLGGLKTDLHSRLL
CHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCHHHHHHHHHH
DAAGSPISGLYAVGEAAGFGGGGASGKRSLEGTFLPGCILTAKAAVKAM
HHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQADLVIAGGGLAGIVTALEALRAGNSVVIVDRDTPERFGGLALWAFGGMALVGTPLQAR
CCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCEEEEHHCCEEEECCCHHHE
MKIPDTPEIALRDWIRFGELDEREHWPLQWARYYVEHSRSEIYDWLSSHGVTFMPAVNWV
ECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHH
ERGLVGDGNALPRYHIVWGTSQRLTRVMIAAMRAADRGGKLTVLHRHRVVGLDRAGGAMA
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCEE
GVIAVNEDSGAEIRIAAPLTVLAMGGINGGHAEARANWVKGRPMPSAMLNGAHPFADGKL
EEEEEECCCCCEEEEECCEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCH
HHHAAETIGAQITHAGEMWNYAAGIPHPFPHFDGHGLSLVPCKSALWLDHRGERIGPQPL
HHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCC
VTGFDTYDLCQRVAAQEKPYTWHLLNWRIAAKEFAISGAEHNARIRERQMPMFLKETLLG
EECCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHEECCCCCCCHHHHHHCCHHHHHHHHC
NHRLVRQMQRESRHFLVDETLAGLAAKMNAFTGTDDIKPEVLQATADAFDANFENGDKLF
CHHHHHHHHHHHCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
NDDQLRRILHARQWGPDKLRTCKPAPLQMRGAGPFIAIHMQLITRKSLGGLKTDLHSRLL
CHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCHHHHHHHHHH
DAAGSPISGLYAVGEAAGFGGGGASGKRSLEGTFLPGCILTAKAAVKAM
HHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA