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The map label for this gene is yheS [H]

Identifier: 146340369

GI number: 146340369

Start: 3588142

End: 3589764

Strand: Direct

Name: yheS [H]

Synonym: BRADO3397

Alternate gene names: 146340369

Gene position: 3588142-3589764 (Clockwise)

Preceding gene: 146340368

Following gene: 146340374

Centisome position: 48.12

GC content: 65.8

Gene sequence:

>1623_bases
ATGATCCGCCTCGACAACATCAGCAAGCAAGTCGGCCACCAGATCCTGTTCATCGAAGCCTCCGCCGCGCTCCAGCGCGG
CGAGAAGATCGGGCTGGTCGGCCCCAACGGGGCCGGCAAGACGACGCTGTTCCGGATGATCTCGGGCCGCGAGCAGCCGG
ACGAGGGCCAGGTCTCGACCGATCGCGGCATCTCCATCGGCTATTTCAACCAGGACGTCGGCGAGATGTCTGGCCGCAGT
GCCGTGGCCGAGGTCATGGACGGGGCAGGGCCGGTGTCCTCGGTCGCCGCCGAGCTCAAGGAACTCGAGGCCGCGATGGC
CGATCCGGACCGCGCCGACGAGATGGACGAGATCATCGCGCGCTACGGCGAGGTGCTGGCACGGTTCGAGGAGCTCGACG
GCTACGCGCTCGACAGCCGCGCCCGCGAGGCGCTGGCCGGCCTCGGCTTCTCCGAGGAGATGATGGACAAGGACGTCGGC
CTGTTGTCCGGCGGCTGGAAGATGCGCGTCGCGCTGGCCCGCATCCTCCTGATGCGTCCCGACGTCATGCTGCTCGACGA
GCCGTCGAACCATCTTGATCTCGAAAGCCTGATCTGGCTCGAGCACTTTCTCAAGGGCTACGAGGGCGCATTGCTGATGA
CCTCGCACGACCGCGAGTTCATCAACCGCATCATCAACAAGGTCATCGAGATCGACGCCGGCCAGCTCACGTCCTATTCC
GGCGACTACGATTTTTACGAGCAGCAGCGGGCGCTGAACGAGAAGCAGCAGCAGGCGCAATATGAGCGCCAGCAGGCGAT
GCTCGCCAAGGAGATCAAGTTCATCGAGCGTTTCAAGGCGCGAGCGTCGCATGCGGCGCAGGTGCAGAGCCGGGTCAAGA
AGCTCGACAAGATCGAGCGCGTCGAGCCGCCCAAGCGCCGCCAGAGCGTGGCGTTCGACTTCCTGCCGGCGCCGCGCTCG
GGTGAGGACGTGGTGGCGCTGAAGAAGGTGTCGAAGAGCTACGGCAGCCGCCGCATCTATGATGGGCTGGACTTCATGAT
CCGGCGCCGCGAGCGCTGGTGCGTGATGGGCGTCAACGGCGCCGGCAAGTCGACCTTGCTGAAGCTCGTCGCGGGCACCG
CGGAGCCCGACGACGGCTCGGTGACGATCGGCGGCAGCGTCAAGATGGGCTATTTCGCGCAGCATGCGATGGACCTGCTC
GACGGTGACGAGACCGTGTTCGAGTCGCTGGAGCATTCCTTTCCGCAGGCCGGGCAGGGCTCGCTGCGCGCGCTGGCCGG
CTGCTTCGGATTCTCGGGCGATGACGTCGAGAAGCGCTGCCGGGTGCTGTCGGGCGGCGAGAAGGCGCGGCTGGTGATGG
CCAAGATGCTCTATGATCCGCCGAACTTCCTGGTGCTGGACGAGCCGACCAACCATCTGGACATGGCGACCAAGCAGATG
CTGATCGAGGCCCTGTCGAACTTCGAGGGCACCATGCTGTTCGTCTCGCACGACCGGCATTTCCTGGCGGCGCTGTCGAA
CCGCGTGCTGGAACTGACGCCTGACGGGCTGCATCAATATGGCGGCGGCTATACGGAATACGTCGCCCGCAGCGGCCACG
AGGCGCCGGGCCTGCGCAGCTGA

Upstream 100 bases:

>100_bases
GGGCCGGTTCGGGACGCCAGTTGCGGTGCAAAATTGCGCCTTCCACCGGCGGCGCGCATCGACTAAGAGCGGCGGCAACC
CGTCCACCGCCTGAGCCCAC

Downstream 100 bases:

>100_bases
TCGCGTGGCGGCTGCCGCGCGTCATTGTTTCAGCCAGTCAAAGACGAGAGGAGCGGCGCGCCGGAGCGTGTCGTCCATCG
CCGGGCCATTACCGGGGGTG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MIRLDNISKQVGHQILFIEASAALQRGEKIGLVGPNGAGKTTLFRMISGREQPDEGQVSTDRGISIGYFNQDVGEMSGRS
AVAEVMDGAGPVSSVAAELKELEAAMADPDRADEMDEIIARYGEVLARFEELDGYALDSRAREALAGLGFSEEMMDKDVG
LLSGGWKMRVALARILLMRPDVMLLDEPSNHLDLESLIWLEHFLKGYEGALLMTSHDREFINRIINKVIEIDAGQLTSYS
GDYDFYEQQRALNEKQQQAQYERQQAMLAKEIKFIERFKARASHAAQVQSRVKKLDKIERVEPPKRRQSVAFDFLPAPRS
GEDVVALKKVSKSYGSRRIYDGLDFMIRRRERWCVMGVNGAGKSTLLKLVAGTAEPDDGSVTIGGSVKMGYFAQHAMDLL
DGDETVFESLEHSFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMAKMLYDPPNFLVLDEPTNHLDMATKQM
LIEALSNFEGTMLFVSHDRHFLAALSNRVLELTPDGLHQYGGGYTEYVARSGHEAPGLRS

Sequences:

>Translated_540_residues
MIRLDNISKQVGHQILFIEASAALQRGEKIGLVGPNGAGKTTLFRMISGREQPDEGQVSTDRGISIGYFNQDVGEMSGRS
AVAEVMDGAGPVSSVAAELKELEAAMADPDRADEMDEIIARYGEVLARFEELDGYALDSRAREALAGLGFSEEMMDKDVG
LLSGGWKMRVALARILLMRPDVMLLDEPSNHLDLESLIWLEHFLKGYEGALLMTSHDREFINRIINKVIEIDAGQLTSYS
GDYDFYEQQRALNEKQQQAQYERQQAMLAKEIKFIERFKARASHAAQVQSRVKKLDKIERVEPPKRRQSVAFDFLPAPRS
GEDVVALKKVSKSYGSRRIYDGLDFMIRRRERWCVMGVNGAGKSTLLKLVAGTAEPDDGSVTIGGSVKMGYFAQHAMDLL
DGDETVFESLEHSFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMAKMLYDPPNFLVLDEPTNHLDMATKQM
LIEALSNFEGTMLFVSHDRHFLAALSNRVLELTPDGLHQYGGGYTEYVARSGHEAPGLRS
>Mature_540_residues
MIRLDNISKQVGHQILFIEASAALQRGEKIGLVGPNGAGKTTLFRMISGREQPDEGQVSTDRGISIGYFNQDVGEMSGRS
AVAEVMDGAGPVSSVAAELKELEAAMADPDRADEMDEIIARYGEVLARFEELDGYALDSRAREALAGLGFSEEMMDKDVG
LLSGGWKMRVALARILLMRPDVMLLDEPSNHLDLESLIWLEHFLKGYEGALLMTSHDREFINRIINKVIEIDAGQLTSYS
GDYDFYEQQRALNEKQQQAQYERQQAMLAKEIKFIERFKARASHAAQVQSRVKKLDKIERVEPPKRRQSVAFDFLPAPRS
GEDVVALKKVSKSYGSRRIYDGLDFMIRRRERWCVMGVNGAGKSTLLKLVAGTAEPDDGSVTIGGSVKMGYFAQHAMDLL
DGDETVFESLEHSFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMAKMLYDPPNFLVLDEPTNHLDMATKQM
LIEALSNFEGTMLFVSHDRHFLAALSNRVLELTPDGLHQYGGGYTEYVARSGHEAPGLRS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=533, Percent_Identity=35.2720450281426, Blast_Score=309, Evalue=5e-84,
Organism=Homo sapiens, GI10947137, Length=536, Percent_Identity=33.3955223880597, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI27881506, Length=536, Percent_Identity=33.3955223880597, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=32.5278810408922, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=32.5278810408922, Blast_Score=233, Evalue=4e-61,
Organism=Escherichia coli, GI1789751, Length=532, Percent_Identity=38.5338345864662, Blast_Score=384, Evalue=1e-107,
Organism=Escherichia coli, GI1787041, Length=537, Percent_Identity=33.7057728119181, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI2367384, Length=510, Percent_Identity=35.4901960784314, Blast_Score=292, Evalue=5e-80,
Organism=Escherichia coli, GI1787182, Length=524, Percent_Identity=32.2519083969466, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87081782, Length=525, Percent_Identity=25.1428571428571, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788165, Length=220, Percent_Identity=29.0909090909091, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=27.9475982532751, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786872, Length=256, Percent_Identity=26.953125, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788225, Length=258, Percent_Identity=26.7441860465116, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789873, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787758, Length=181, Percent_Identity=28.7292817679558, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=32.8125, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=533, Percent_Identity=34.1463414634146, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17555318, Length=519, Percent_Identity=33.140655105973, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17559834, Length=547, Percent_Identity=30.3473491773309, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71983510, Length=285, Percent_Identity=25.6140350877193, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=285, Percent_Identity=25.6140350877193, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=285, Percent_Identity=25.6140350877193, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320874, Length=541, Percent_Identity=32.5323475046211, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321121, Length=552, Percent_Identity=30.9782608695652, Blast_Score=272, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6325030, Length=391, Percent_Identity=28.6445012787724, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=415, Percent_Identity=25.7831325301205, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323278, Length=410, Percent_Identity=26.5853658536585, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24666836, Length=534, Percent_Identity=34.0823970037453, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24642252, Length=514, Percent_Identity=31.9066147859922, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI18859989, Length=514, Percent_Identity=31.9066147859922, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24641342, Length=539, Percent_Identity=29.8701298701299, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI116007184, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221500365, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59860; Mature: 59860

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLDNISKQVGHQILFIEASAALQRGEKIGLVGPNGAGKTTLFRMISGREQPDEGQVST
CCCCCCHHHHHCCEEEEEEHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCC
DRGISIGYFNQDVGEMSGRSAVAEVMDGAGPVSSVAAELKELEAAMADPDRADEMDEIIA
CCCCEEEECCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYGEVLARFEELDGYALDSRAREALAGLGFSEEMMDKDVGLLSGGWKMRVALARILLMRP
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
DVMLLDEPSNHLDLESLIWLEHFLKGYEGALLMTSHDREFINRIINKVIEIDAGQLTSYS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
GDYDFYEQQRALNEKQQQAQYERQQAMLAKEIKFIERFKARASHAAQVQSRVKKLDKIER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VEPPKRRQSVAFDFLPAPRSGEDVVALKKVSKSYGSRRIYDGLDFMIRRRERWCVMGVNG
CCCCHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
AGKSTLLKLVAGTAEPDDGSVTIGGSVKMGYFAQHAMDLLDGDETVFESLEHSFPQAGQG
CCHHHHHHHHHCCCCCCCCCEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
SLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMAKMLYDPPNFLVLDEPTNHLDMATKQM
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
LIEALSNFEGTMLFVSHDRHFLAALSNRVLELTPDGLHQYGGGYTEYVARSGHEAPGLRS
HHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIRLDNISKQVGHQILFIEASAALQRGEKIGLVGPNGAGKTTLFRMISGREQPDEGQVST
CCCCCCHHHHHCCEEEEEEHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCC
DRGISIGYFNQDVGEMSGRSAVAEVMDGAGPVSSVAAELKELEAAMADPDRADEMDEIIA
CCCCEEEECCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYGEVLARFEELDGYALDSRAREALAGLGFSEEMMDKDVGLLSGGWKMRVALARILLMRP
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
DVMLLDEPSNHLDLESLIWLEHFLKGYEGALLMTSHDREFINRIINKVIEIDAGQLTSYS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
GDYDFYEQQRALNEKQQQAQYERQQAMLAKEIKFIERFKARASHAAQVQSRVKKLDKIER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VEPPKRRQSVAFDFLPAPRSGEDVVALKKVSKSYGSRRIYDGLDFMIRRRERWCVMGVNG
CCCCHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
AGKSTLLKLVAGTAEPDDGSVTIGGSVKMGYFAQHAMDLLDGDETVFESLEHSFPQAGQG
CCHHHHHHHHHCCCCCCCCCEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
SLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMAKMLYDPPNFLVLDEPTNHLDMATKQM
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
LIEALSNFEGTMLFVSHDRHFLAALSNRVLELTPDGLHQYGGGYTEYVARSGHEAPGLRS
HHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]