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The map label for this gene is glsA1 [H]

Identifier: 146340115

GI number: 146340115

Start: 3325604

End: 3327466

Strand: Reverse

Name: glsA1 [H]

Synonym: BRADO3130

Alternate gene names: 146340115

Gene position: 3327466-3325604 (Counterclockwise)

Preceding gene: 146340118

Following gene: 146340114

Centisome position: 44.62

GC content: 67.85

Gene sequence:

>1863_bases
ATGACCACCGACACTCCGCGCCCACATCGCAATCCGCAGCACTGGGCCTCCGCCGCAATGCCTCCGCTGCAGCGCTTCCT
CTCGGCCTGCCACGCCGACTTCTGGCCCGATCATGACGGCGCGGTCGCGAACTACATTCCCGAGCTGGGCAAGGCGGACC
CCGCGCATTTCGGCATCAGCCTCGCCACGCTCGACGGCCATGTCTACGAGGTCGGCGACAGCCGCGTGCCGTTCACGATC
CAGTCGATGTCGAAGCCGTTCGTCTTCGCGCTCGCGCTCGACATTCTCGGCTCCGACGCCGTCGAGCGCGTGATCGGCGT
CGAGCCTTCCGGCGATCCCTTCAATTCGATCCGGCTCAATGCCGACAATCATCCGTTCAATGCGATGGTCAATGCCGGCG
CGATCGCCTGCAGCGGCCTCGTGCGCGGGGCCCGGCACGCCGACGCGTTCGAGACCATCCGCGACGCGCTTGGCCGCTTC
GCCGGCCGCAAGCTCGATGTCGACGACGCCGTATTCGCCTCGGAAGCGGCGACCGGCGACCGCAACCGCGCCATCGCCTA
TCTGCTGCGGACGTCCGGGGTCATCAGCGAGCCGGTCGACGACGTGCTCGCGGTGTACTTCCGGCAATGCGCCGTGCTCG
TCACGGCGCGCGATTGCGCCATCATGGCGGCGACGCTCGCCAATCGCGGCGTCAATCCAGTGACCGGCGAGCAGGTCGTG
ACGCCCTATGCGGTGTCCCGCACGCTCTCGGTCATGACCTCGTCGGGCATGTATGACTTTGCGGGCGAATGGATCTATCG
CGTCGGCATTCCGGCCAAGAGCGGCGTCGGCGGCGGCATACTGGCGAGCCTGCCGGCGCGGCTCGGGCTCGGCAGCTACT
CGCCGCGGCTTGATGGCCATGGCAACAGCGCGCGCGGCATCAAGGTCTGCGAGGCGCTGTCGGCGCATTACGGCCTGCAC
ATGCTGAATCGCTCGGACGACGCGCGGACCACGATCATCGCCGATTACGACATCGGCGCCAGTCCGTCGCGGCGCAGCCG
CCGCACCCAGGAGCGCGAGATCCTCGCCGCGCACCCCGACGCCGTGCGCGTGCTAGAGTTGGTCGGTACGCTGTCGCTCT
CGAATGTCGACTACGTCTCGCGCCAGCTGGCCGCGGGCGAGCGCCCGCAATTCGTGATCTTCGATCTGCACCGCGTCACC
GCGATGACGCCAGCCGGCCTGCGTCTGCTGGCCGAGCTGTTTCACGAGCTCGCAGATTTCCACGTCACCGTCGTGCTCTC
CGGCCTCCGCCGGACCTCGCCGGAATGGCAGGAGATCACGGCGCGCACCGGCGACATCCGCAACGTGCGCGACTTCTATC
TGCTCGACACTGCGATCGAATGGGCCGAGGACCAGATCGTCTATCGCTACGGCGGCGCGATCGACTTCCTCGAAACCACC
GAGCTTGCCGAGCAGCCGCTGCTGGCCGGCCTCTCCGCCGACGAGCGCCACGAACTGGCCGCGCTGGCCACGATCCGGCA
CTATCAGCAGAGCGAGCGCATCCTGTCCGCGGGAGAGGCAGCGAGCTCGCTGTTCTTCCTGCGCTCCGGCGTGGTCCATG
TCACCCTGCCCGACGGCATCCGGCTGGCCACGCTGACGGCGGGGCAATGCTTCGGCGAAATGGCCTTGCTCGAGTCGGCA
AGATCTGCCGACGTGACGGCCGACTTCTCGGCGACAGCGTTCGAGATCGCGCTGGATGATTTCGAGCGTTTCCGGGCGCG
GCATCCGCGCGCCGGCGAGCGGATCATGCGCAACCTCGCGCAGCTGCTGGCGGAGCGCCTGACGATCGCCAATGCGCGGC
TGAATCTGCTGGCTGCTGATTGA

Upstream 100 bases:

>100_bases
AGCAGCGGCAACAATTGACCAGCCCTGCACCAAGTGTGGGCTGGCTGCTCCGACGGGGCTGCGACATAACCGGCGCCATC
CGTGCCGCATCGAGTCCCCC

Downstream 100 bases:

>100_bases
GATTGTCATCACAACGTCATATATCGTCGAATCATTTTAAAATCTAAGGTTGTGTTCGCGGCAGCTAATAGCCTTCGGTC
GTTATACTCATCACTCGTAT

Product: putative glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTTDTPRPHRNPQHWASAAMPPLQRFLSACHADFWPDHDGAVANYIPELGKADPAHFGISLATLDGHVYEVGDSRVPFTI
QSMSKPFVFALALDILGSDAVERVIGVEPSGDPFNSIRLNADNHPFNAMVNAGAIACSGLVRGARHADAFETIRDALGRF
AGRKLDVDDAVFASEAATGDRNRAIAYLLRTSGVISEPVDDVLAVYFRQCAVLVTARDCAIMAATLANRGVNPVTGEQVV
TPYAVSRTLSVMTSSGMYDFAGEWIYRVGIPAKSGVGGGILASLPARLGLGSYSPRLDGHGNSARGIKVCEALSAHYGLH
MLNRSDDARTTIIADYDIGASPSRRSRRTQEREILAAHPDAVRVLELVGTLSLSNVDYVSRQLAAGERPQFVIFDLHRVT
AMTPAGLRLLAELFHELADFHVTVVLSGLRRTSPEWQEITARTGDIRNVRDFYLLDTAIEWAEDQIVYRYGGAIDFLETT
ELAEQPLLAGLSADERHELAALATIRHYQQSERILSAGEAASSLFFLRSGVVHVTLPDGIRLATLTAGQCFGEMALLESA
RSADVTADFSATAFEIALDDFERFRARHPRAGERIMRNLAQLLAERLTIANARLNLLAAD

Sequences:

>Translated_620_residues
MTTDTPRPHRNPQHWASAAMPPLQRFLSACHADFWPDHDGAVANYIPELGKADPAHFGISLATLDGHVYEVGDSRVPFTI
QSMSKPFVFALALDILGSDAVERVIGVEPSGDPFNSIRLNADNHPFNAMVNAGAIACSGLVRGARHADAFETIRDALGRF
AGRKLDVDDAVFASEAATGDRNRAIAYLLRTSGVISEPVDDVLAVYFRQCAVLVTARDCAIMAATLANRGVNPVTGEQVV
TPYAVSRTLSVMTSSGMYDFAGEWIYRVGIPAKSGVGGGILASLPARLGLGSYSPRLDGHGNSARGIKVCEALSAHYGLH
MLNRSDDARTTIIADYDIGASPSRRSRRTQEREILAAHPDAVRVLELVGTLSLSNVDYVSRQLAAGERPQFVIFDLHRVT
AMTPAGLRLLAELFHELADFHVTVVLSGLRRTSPEWQEITARTGDIRNVRDFYLLDTAIEWAEDQIVYRYGGAIDFLETT
ELAEQPLLAGLSADERHELAALATIRHYQQSERILSAGEAASSLFFLRSGVVHVTLPDGIRLATLTAGQCFGEMALLESA
RSADVTADFSATAFEIALDDFERFRARHPRAGERIMRNLAQLLAERLTIANARLNLLAAD
>Mature_619_residues
TTDTPRPHRNPQHWASAAMPPLQRFLSACHADFWPDHDGAVANYIPELGKADPAHFGISLATLDGHVYEVGDSRVPFTIQ
SMSKPFVFALALDILGSDAVERVIGVEPSGDPFNSIRLNADNHPFNAMVNAGAIACSGLVRGARHADAFETIRDALGRFA
GRKLDVDDAVFASEAATGDRNRAIAYLLRTSGVISEPVDDVLAVYFRQCAVLVTARDCAIMAATLANRGVNPVTGEQVVT
PYAVSRTLSVMTSSGMYDFAGEWIYRVGIPAKSGVGGGILASLPARLGLGSYSPRLDGHGNSARGIKVCEALSAHYGLHM
LNRSDDARTTIIADYDIGASPSRRSRRTQEREILAAHPDAVRVLELVGTLSLSNVDYVSRQLAAGERPQFVIFDLHRVTA
MTPAGLRLLAELFHELADFHVTVVLSGLRRTSPEWQEITARTGDIRNVRDFYLLDTAIEWAEDQIVYRYGGAIDFLETTE
LAEQPLLAGLSADERHELAALATIRHYQQSERILSAGEAASSLFFLRSGVVHVTLPDGIRLATLTAGQCFGEMALLESAR
SADVTADFSATAFEIALDDFERFRARHPRAGERIMRNLAQLLAERLTIANARLNLLAAD

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=285, Percent_Identity=44.9122807017544, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI20336214, Length=285, Percent_Identity=43.5087719298246, Blast_Score=247, Evalue=2e-65,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=37.6237623762376, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1787804, Length=282, Percent_Identity=36.8794326241135, Blast_Score=179, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17507019, Length=332, Percent_Identity=38.5542168674699, Blast_Score=235, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17532727, Length=287, Percent_Identity=40.7665505226481, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI193204073, Length=303, Percent_Identity=36.963696369637, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI193204075, Length=305, Percent_Identity=36.0655737704918, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI281363239, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24653158, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24653156, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI281363241, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24653166, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24653164, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24653162, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=8e-58,
Organism=Drosophila melanogaster, GI116008307, Length=289, Percent_Identity=37.0242214532872, Blast_Score=222, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR015868
- InterPro:   IPR014710
- InterPro:   IPR002645 [H]

Pfam domain/function: PF00027 cNMP_binding; PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 67359; Mature: 67228

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDTPRPHRNPQHWASAAMPPLQRFLSACHADFWPDHDGAVANYIPELGKADPAHFGIS
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHCEE
LATLDGHVYEVGDSRVPFTIQSMSKPFVFALALDILGSDAVERVIGVEPSGDPFNSIRLN
EEEECCEEEECCCCCCCEEHHCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEC
ADNHPFNAMVNAGAIACSGLVRGARHADAFETIRDALGRFAGRKLDVDDAVFASEAATGD
CCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
RNRAIAYLLRTSGVISEPVDDVLAVYFRQCAVLVTARDCAIMAATLANRGVNPVTGEQVV
CCHHEEEEEHHCCCCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCCEE
TPYAVSRTLSVMTSSGMYDFAGEWIYRVGIPAKSGVGGGILASLPARLGLGSYSPRLDGH
CHHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GNSARGIKVCEALSAHYGLHMLNRSDDARTTIIADYDIGASPSRRSRRTQEREILAAHPD
CCCCCHHHHHHHHHHHHCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
AVRVLELVGTLSLSNVDYVSRQLAAGERPQFVIFDLHRVTAMTPAGLRLLAELFHELADF
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHHH
HVTVVLSGLRRTSPEWQEITARTGDIRNVRDFYLLDTAIEWAEDQIVYRYGGAIDFLETT
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEECHHHHH
ELAEQPLLAGLSADERHELAALATIRHYQQSERILSAGEAASSLFFLRSGVVHVTLPDGI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCE
RLATLTAGQCFGEMALLESARSADVTADFSATAFEIALDDFERFRARHPRAGERIMRNLA
EEEEEEHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLLAERLTIANARLNLLAAD
HHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure 
TTDTPRPHRNPQHWASAAMPPLQRFLSACHADFWPDHDGAVANYIPELGKADPAHFGIS
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHCEE
LATLDGHVYEVGDSRVPFTIQSMSKPFVFALALDILGSDAVERVIGVEPSGDPFNSIRLN
EEEECCEEEECCCCCCCEEHHCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEC
ADNHPFNAMVNAGAIACSGLVRGARHADAFETIRDALGRFAGRKLDVDDAVFASEAATGD
CCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
RNRAIAYLLRTSGVISEPVDDVLAVYFRQCAVLVTARDCAIMAATLANRGVNPVTGEQVV
CCHHEEEEEHHCCCCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCCEE
TPYAVSRTLSVMTSSGMYDFAGEWIYRVGIPAKSGVGGGILASLPARLGLGSYSPRLDGH
CHHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GNSARGIKVCEALSAHYGLHMLNRSDDARTTIIADYDIGASPSRRSRRTQEREILAAHPD
CCCCCHHHHHHHHHHHHCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
AVRVLELVGTLSLSNVDYVSRQLAAGERPQFVIFDLHRVTAMTPAGLRLLAELFHELADF
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHHH
HVTVVLSGLRRTSPEWQEITARTGDIRNVRDFYLLDTAIEWAEDQIVYRYGGAIDFLETT
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEECHHHHH
ELAEQPLLAGLSADERHELAALATIRHYQQSERILSAGEAASSLFFLRSGVVHVTLPDGI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCE
RLATLTAGQCFGEMALLESARSADVTADFSATAFEIALDDFERFRARHPRAGERIMRNLA
EEEEEEHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLLAERLTIANARLNLLAAD
HHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]