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The map label for this gene is ygjG [C]

Identifier: 146339621

GI number: 146339621

Start: 2802121

End: 2803464

Strand: Reverse

Name: ygjG [C]

Synonym: BRADO2614

Alternate gene names: 146339621

Gene position: 2803464-2802121 (Counterclockwise)

Preceding gene: 146339622

Following gene: 146339620

Centisome position: 37.6

GC content: 68.01

Gene sequence:

>1344_bases
ATGACGACCACCTCTTCCGCCCCCCACGATCCCGTGCTCACCGATGCGCAGCTGAATTCGTTCTGGATGCCGTTCACGCC
GAACCGGCAATTCAAGACCAATCCGCGCCTGTTCGTCGCCGCGGAAGGCATGCACTACATCAAGCCTGACGGCGGTCGCG
TGCTCGACGCGATGGCCGGGCTGTGGTGCGTCAACGCCGGCCATGGCCAGCGGCGCATCGTCGAGGCGATCCAGGCGCAA
GCCGCCAAGCTCGATTTCGTCTCGTCGTTCCAGATGAGCCACCCGGCCGCGTTCGAGCTCGCTGCCCGCATTGTCGCGAT
CGCGCCGGACGGATTGGACCACGTCTTCTTCACCAACTCCGGATCGGAGTCCGTCGACACCGCGCTGAAGATCGCCCGCG
CCTACCACCGCGCCCGCGGACAAGGCGAACGCATCCGCTTCATCAGCCGCGCCCGCGCCTATCACGGCATGGGCTGGGGC
GGCCTCTCGGTGAGCGGCCTGTCGCGCCACCGTCGCGACTTCGGACCGTTGCTGCCCGAGATCGATCATCTGCCGCACAC
CCACGATCCCGAACGCGCGGCATTCTCGCGCGGCCAGCCACATTGGGGCGTGCACTTCGCCGACGAGTTGGAGAAGCTGC
TGGCGCTGCATGATCCCGCGACGGTCGCCGCTGTCATCGTCGAGCCGGTCACCGGCTCGGGCGGCGTGCTGCCGCCGCCG
GTCGGCTATCTCGAGCGGCTGCGCGAGATCTGCGACCGCAACGGCATTCTGTTGATCTTCGACGAGGTCATCACCGGCTT
CGGCCGGGTCGGTGCGGCGTTTGCCGCCAATGCCTTCGGCGTGACGCCTGACATCATCACCTGTGCCAAGGGCATGACCA
ACGGCGCGGTGCCGATGGGCGGCGTCATCGTCCACCGCAACATCCACGATACGATGATGAGCGGTCCGGCGGGGATCGAG
CTGTTTCACGGCTATACTTATTCCGCCCATCCGCTCGCCTGCGCCGCGGCGCTCGCGACGCTCGACGTCTACCAGGAGCA
GGATCTGTTCGGCCGCGCCGAGCGGGTCGCTCCGTTGTGGGAAAACGCCGTTCACGCGCTGCGCCAGGCCCCGCACGTGA
TCGACATCCGCAACATCGGCCTGCTCGCCGCGATCGATCTCAAGCCGCGCGACGGCGCGCCGGGCGCCCGCGGCAGCGAA
TGCGCGGCGCGCTGCTTCGAAGACGGCGTGCTGATCCGCGGCTCCAGCGACACGCTGGTGCTGTCGCCGCCCCTGATCGT
GTCCGAGGAGCAGATCGGCGCGGTCTTCCGCACCATTCGCCAGGCGCTGGACGCGCTCGACTGA

Upstream 100 bases:

>100_bases
CGCCATCTCGAAAGCGCCGCAGCGCTCAGGCGGCCGCCGGGCAATGGCCGCAAATCCACGTGATGATCACGACAAGACCC
GCTCGTTCCGGAGTGTCCCC

Downstream 100 bases:

>100_bases
GCGCGGCCGCGCCCGGCCATTTTGCGAGACCGGTGATCCACGGGCACGGGGGTTCCGTTTCCCTACTTTCGGAGAGCCCC
CACGTGCGCAACACAGCCAA

Product: omega amino acid--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTTTSSAPHDPVLTDAQLNSFWMPFTPNRQFKTNPRLFVAAEGMHYIKPDGGRVLDAMAGLWCVNAGHGQRRIVEAIQAQ
AAKLDFVSSFQMSHPAAFELAARIVAIAPDGLDHVFFTNSGSESVDTALKIARAYHRARGQGERIRFISRARAYHGMGWG
GLSVSGLSRHRRDFGPLLPEIDHLPHTHDPERAAFSRGQPHWGVHFADELEKLLALHDPATVAAVIVEPVTGSGGVLPPP
VGYLERLREICDRNGILLIFDEVITGFGRVGAAFAANAFGVTPDIITCAKGMTNGAVPMGGVIVHRNIHDTMMSGPAGIE
LFHGYTYSAHPLACAAALATLDVYQEQDLFGRAERVAPLWENAVHALRQAPHVIDIRNIGLLAAIDLKPRDGAPGARGSE
CAARCFEDGVLIRGSSDTLVLSPPLIVSEEQIGAVFRTIRQALDALD

Sequences:

>Translated_447_residues
MTTTSSAPHDPVLTDAQLNSFWMPFTPNRQFKTNPRLFVAAEGMHYIKPDGGRVLDAMAGLWCVNAGHGQRRIVEAIQAQ
AAKLDFVSSFQMSHPAAFELAARIVAIAPDGLDHVFFTNSGSESVDTALKIARAYHRARGQGERIRFISRARAYHGMGWG
GLSVSGLSRHRRDFGPLLPEIDHLPHTHDPERAAFSRGQPHWGVHFADELEKLLALHDPATVAAVIVEPVTGSGGVLPPP
VGYLERLREICDRNGILLIFDEVITGFGRVGAAFAANAFGVTPDIITCAKGMTNGAVPMGGVIVHRNIHDTMMSGPAGIE
LFHGYTYSAHPLACAAALATLDVYQEQDLFGRAERVAPLWENAVHALRQAPHVIDIRNIGLLAAIDLKPRDGAPGARGSE
CAARCFEDGVLIRGSSDTLVLSPPLIVSEEQIGAVFRTIRQALDALD
>Mature_446_residues
TTTSSAPHDPVLTDAQLNSFWMPFTPNRQFKTNPRLFVAAEGMHYIKPDGGRVLDAMAGLWCVNAGHGQRRIVEAIQAQA
AKLDFVSSFQMSHPAAFELAARIVAIAPDGLDHVFFTNSGSESVDTALKIARAYHRARGQGERIRFISRARAYHGMGWGG
LSVSGLSRHRRDFGPLLPEIDHLPHTHDPERAAFSRGQPHWGVHFADELEKLLALHDPATVAAVIVEPVTGSGGVLPPPV
GYLERLREICDRNGILLIFDEVITGFGRVGAAFAANAFGVTPDIITCAKGMTNGAVPMGGVIVHRNIHDTMMSGPAGIEL
FHGYTYSAHPLACAAALATLDVYQEQDLFGRAERVAPLWENAVHALRQAPHVIDIRNIGLLAAIDLKPRDGAPGARGSEC
AARCFEDGVLIRGSSDTLVLSPPLIVSEEQIGAVFRTIRQALDALD

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=29.9303944315545, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=30.1624129930394, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4557809, Length=405, Percent_Identity=28.1481481481481, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=30.8860759493671, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI284507298, Length=328, Percent_Identity=29.5731707317073, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI13994255, Length=419, Percent_Identity=26.7303102625298, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=26.8065268065268, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=34.7290640394089, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786991, Length=432, Percent_Identity=31.712962962963, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789759, Length=422, Percent_Identity=28.9099526066351, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789016, Length=418, Percent_Identity=29.4258373205742, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=29.25, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=28.125, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=28.955223880597, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=28.4738041002278, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=412, Percent_Identity=26.2135922330097, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=446, Percent_Identity=28.0269058295964, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=215, Percent_Identity=31.6279069767442, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323470, Length=420, Percent_Identity=28.0952380952381, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=476, Percent_Identity=25.4201680672269, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=457, Percent_Identity=26.6958424507659, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21357415, Length=413, Percent_Identity=28.8135593220339, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI161085790, Length=450, Percent_Identity=29.5555555555556, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28574759, Length=434, Percent_Identity=29.7235023041475, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=26.9767441860465, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48250; Mature: 48118

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTSSAPHDPVLTDAQLNSFWMPFTPNRQFKTNPRLFVAAEGMHYIKPDGGRVLDAMAG
CCCCCCCCCCCCEECCCCCCEECCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHH
LWCVNAGHGQRRIVEAIQAQAAKLDFVSSFQMSHPAAFELAARIVAIAPDGLDHVFFTNS
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEECCCCCCEEEEECC
GSESVDTALKIARAYHRARGQGERIRFISRARAYHGMGWGGLSVSGLSRHRRDFGPLLPE
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCH
IDHLPHTHDPERAAFSRGQPHWGVHFADELEKLLALHDPATVAAVIVEPVTGSGGVLPPP
HHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCCC
VGYLERLREICDRNGILLIFDEVITGFGRVGAAFAANAFGVTPDIITCAKGMTNGAVPMG
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
GVIVHRNIHDTMMSGPAGIELFHGYTYSAHPLACAAALATLDVYQEQDLFGRAERVAPLW
CEEEECCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAVHALRQAPHVIDIRNIGLLAAIDLKPRDGAPGARGSECAARCFEDGVLIRGSSDTLV
HHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEE
LSPPLIVSEEQIGAVFRTIRQALDALD
ECCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTTSSAPHDPVLTDAQLNSFWMPFTPNRQFKTNPRLFVAAEGMHYIKPDGGRVLDAMAG
CCCCCCCCCCCEECCCCCCEECCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHH
LWCVNAGHGQRRIVEAIQAQAAKLDFVSSFQMSHPAAFELAARIVAIAPDGLDHVFFTNS
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEECCCCCCEEEEECC
GSESVDTALKIARAYHRARGQGERIRFISRARAYHGMGWGGLSVSGLSRHRRDFGPLLPE
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCH
IDHLPHTHDPERAAFSRGQPHWGVHFADELEKLLALHDPATVAAVIVEPVTGSGGVLPPP
HHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCCC
VGYLERLREICDRNGILLIFDEVITGFGRVGAAFAANAFGVTPDIITCAKGMTNGAVPMG
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
GVIVHRNIHDTMMSGPAGIELFHGYTYSAHPLACAAALATLDVYQEQDLFGRAERVAPLW
CEEEECCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAVHALRQAPHVIDIRNIGLLAAIDLKPRDGAPGARGSECAARCFEDGVLIRGSSDTLV
HHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEE
LSPPLIVSEEQIGAVFRTIRQALDALD
ECCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]