| Definition | Bradyrhizobium sp. ORS278 chromosome, complete genome. |
|---|---|
| Accession | NC_009445 |
| Length | 7,456,587 |
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The map label for this gene is caiD [H]
Identifier: 146339583
GI number: 146339583
Start: 2755053
End: 2755832
Strand: Reverse
Name: caiD [H]
Synonym: BRADO2574
Alternate gene names: 146339583
Gene position: 2755832-2755053 (Counterclockwise)
Preceding gene: 146339585
Following gene: 146339579
Centisome position: 36.96
GC content: 67.95
Gene sequence:
>780_bases ATGGAGCTGAAATTCTCGAAGATCACGCGCAAGGGACCGGTCACGATCGTGACCCTGGCGCGCCCCGAGGTCTACAACGC GCTGCATACCGACGCCCATTACGAGCTCGAAGCGGTGTTCGACGGCTTCGCCGCCGATCCCGAGCAATGGGTCGCGATCG TCACCGGCGAGGGCGACAAGGCGTTCTGCGCCGGCAACGACCTGAAATGGCAGGCGGCCGGCGGCAAGCGCGGCTGGGGC CGAAGCGGCTTCGGCGGCCTGACCTCGCGCTTCGACTGCGACAAGCCGCTGATCGCCGCCGTCAACGGCGTCGCGATGGG CGGCGGCTTCGAGATCGCGCTGGCCTGCGACCTGATCATCGCCTCTGAGAATGCCACCTTCGCGCTGCCCGAACCGCGTG TCGGCCTCGCCGCGCTCGCCGGCGGCCTGCAGCGGCTGCCGCGTCAGATCGGCATGAAGCGCGCGATGGGCATGATCCTG ACCGGCCGCCATGTCGGCGCCCGCGAGGGCCATGAGCTCGGCTTCGTCAACGAAGTGGTGCCGCAAGGCGAAGCACTGTC GGCCGCGGAACGCTGGGCCGAGACCATCGCCAAGAACTCGCCGATGTCGATCCGCGCCTCCAAGCAAGCGATCGAGAAGG GCCTCGCGGTCTCGCTGGAGCAGGCCATCACCGAGCAGCGCGATTATCCCGCCGTGCAGGCGATGATCCATTCGCAGGAC TACATCGAGGGTCCCAAGGCGTTCTCGGAGAAGCGGGCGCCGAACTGGCTGGGGCGGTAA
Upstream 100 bases:
>100_bases TTGTGGCGCGCAGCGCGGTTGCGTATTTGGATGGCCGCGCACGCGGCACAGGCGCTAAGCTCCCGCAACGTTGCCAATCA GAAAGCAGGAGGAACGACCG
Downstream 100 bases:
>100_bases CTCCTCGCTGAGCTCGTCATTCCAGTGCGCGACGCAGTCGCGAGCCCGGAATCCATAACCACGATCGGGAGTATGGATTC CTCGCCTGCGCCTTGCGGCG
Product: enoyl-CoA hydratase
Products: L-Carnitine.; L-carnitinyl-CoA [C]
Alternate protein names: Crotonobetainyl-CoA hydratase [H]
Number of amino acids: Translated: 259; Mature: 259
Protein sequence:
>259_residues MELKFSKITRKGPVTIVTLARPEVYNALHTDAHYELEAVFDGFAADPEQWVAIVTGEGDKAFCAGNDLKWQAAGGKRGWG RSGFGGLTSRFDCDKPLIAAVNGVAMGGGFEIALACDLIIASENATFALPEPRVGLAALAGGLQRLPRQIGMKRAMGMIL TGRHVGAREGHELGFVNEVVPQGEALSAAERWAETIAKNSPMSIRASKQAIEKGLAVSLEQAITEQRDYPAVQAMIHSQD YIEGPKAFSEKRAPNWLGR
Sequences:
>Translated_259_residues MELKFSKITRKGPVTIVTLARPEVYNALHTDAHYELEAVFDGFAADPEQWVAIVTGEGDKAFCAGNDLKWQAAGGKRGWG RSGFGGLTSRFDCDKPLIAAVNGVAMGGGFEIALACDLIIASENATFALPEPRVGLAALAGGLQRLPRQIGMKRAMGMIL TGRHVGAREGHELGFVNEVVPQGEALSAAERWAETIAKNSPMSIRASKQAIEKGLAVSLEQAITEQRDYPAVQAMIHSQD YIEGPKAFSEKRAPNWLGR >Mature_259_residues MELKFSKITRKGPVTIVTLARPEVYNALHTDAHYELEAVFDGFAADPEQWVAIVTGEGDKAFCAGNDLKWQAAGGKRGWG RSGFGGLTSRFDCDKPLIAAVNGVAMGGGFEIALACDLIIASENATFALPEPRVGLAALAGGLQRLPRQIGMKRAMGMIL TGRHVGAREGHELGFVNEVVPQGEALSAAERWAETIAKNSPMSIRASKQAIEKGLAVSLEQAITEQRDYPAVQAMIHSQD YIEGPKAFSEKRAPNWLGR
Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=34.2741935483871, Blast_Score=134, Evalue=8e-32, Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=30.3149606299213, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI20127408, Length=249, Percent_Identity=29.3172690763052, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=31.3953488372093, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI37594469, Length=200, Percent_Identity=30, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI37594471, Length=226, Percent_Identity=30.5309734513274, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI31542718, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=29.0196078431373, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI68989263, Length=200, Percent_Identity=31, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI45643119, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI260275230, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI260274832, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4757966, Length=218, Percent_Identity=25.6880733944954, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI51538581, Length=218, Percent_Identity=25.6880733944954, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI25453481, Length=248, Percent_Identity=24.5967741935484, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI51538573, Length=248, Percent_Identity=24.5967741935484, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=43.2432432432432, Blast_Score=196, Evalue=2e-51, Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=35.5731225296443, Blast_Score=150, Evalue=8e-38, Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=30.7692307692308, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=33.4586466165414, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1788682, Length=250, Percent_Identity=29.2, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI87082183, Length=208, Percent_Identity=29.3269230769231, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1790281, Length=176, Percent_Identity=30.6818181818182, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17554946, Length=255, Percent_Identity=35.2941176470588, Blast_Score=148, Evalue=3e-36, Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=36.8852459016393, Blast_Score=145, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17560910, Length=254, Percent_Identity=32.2834645669291, Blast_Score=118, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=32.0175438596491, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17534483, Length=238, Percent_Identity=31.0924369747899, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17536985, Length=276, Percent_Identity=27.536231884058, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17535521, Length=214, Percent_Identity=27.5700934579439, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17549921, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17558304, Length=235, Percent_Identity=27.2340425531915, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI25144276, Length=231, Percent_Identity=29.004329004329, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508951, Length=231, Percent_Identity=29.004329004329, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508953, Length=231, Percent_Identity=29.004329004329, Blast_Score=81, Evalue=6e-16, Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=24.8677248677249, Blast_Score=69, Evalue=8e-13, Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=36.0995850622407, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=36.0995850622407, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=34.2412451361868, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21357171, Length=271, Percent_Identity=30.9963099630996, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI19920382, Length=230, Percent_Identity=31.304347826087, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24650670, Length=209, Percent_Identity=31.1004784688995, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI19922422, Length=247, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI19921000, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24583077, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24583079, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24654903, Length=182, Percent_Identity=25.8241758241758, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571729, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI28571730, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022852 - InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: 4.2.1.- [C]
Molecular weight: Translated: 27832; Mature: 27832
Theoretical pI: Translated: 7.05; Mature: 7.05
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELKFSKITRKGPVTIVTLARPEVYNALHTDAHYELEAVFDGFAADPEQWVAIVTGEGDK CCCCHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEHHHHHCCCCCCCCCEEEEEECCCCE AFCAGNDLKWQAAGGKRGWGRSGFGGLTSRFDCDKPLIAAVNGVAMGGGFEIALACDLII EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEECCCEEEEEEEEEEE ASENATFALPEPRVGLAALAGGLQRLPRQIGMKRAMGMILTGRHVGAREGHELGFVNEVV ECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHC PQGEALSAAERWAETIAKNSPMSIRASKQAIEKGLAVSLEQAITEQRDYPAVQAMIHSQD CCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH YIEGPKAFSEKRAPNWLGR HCCCCHHHHHHCCCCCCCC >Mature Secondary Structure MELKFSKITRKGPVTIVTLARPEVYNALHTDAHYELEAVFDGFAADPEQWVAIVTGEGDK CCCCHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEHHHHHCCCCCCCCCEEEEEECCCCE AFCAGNDLKWQAAGGKRGWGRSGFGGLTSRFDCDKPLIAAVNGVAMGGGFEIALACDLII EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEECCCEEEEEEEEEEE ASENATFALPEPRVGLAALAGGLQRLPRQIGMKRAMGMILTGRHVGAREGHELGFVNEVV ECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHC PQGEALSAAERWAETIAKNSPMSIRASKQAIEKGLAVSLEQAITEQRDYPAVQAMIHSQD CCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH YIEGPKAFSEKRAPNWLGR HCCCCHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: D-Carnitine; D-carnitinyl-CoA [C]
Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]
General reaction: Isomerases [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA