BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is fabG [H]

Identifier: 146339579

GI number: 146339579

Start: 2751693

End: 2752553

Strand: Reverse

Name: fabG [H]

Synonym: BRADO2570

Alternate gene names: 146339579

Gene position: 2752553-2751693 (Counterclockwise)

Preceding gene: 146339583

Following gene: 146339578

Centisome position: 36.91

GC content: 66.2

Gene sequence:

>861_bases
TTGCGCTTCGCTTGTCCATGGTTGCGTCATCCCAATAACGGAAGCGACGCACAGCGTCCTCACATCATCACGGAAACGCT
CATGACCCCGTTCGATCTCACCGGCCGCGTGGCGGTCGTCACCGGCGGCAATGGAGGGATAGGCCTCGGCATCGCCCAGG
CACTTGCGTCCAGTGGCTGCAACGTCTCGATCTGGGGACGCAACACGGAGAAGAACAAGGCGGCTGCCGCGTCGATGGCC
GCAGGCCCTGGCAAGGTCGACACGCGCATCTGCGACGTGACGAGCCCCGCCTCCGTCGCTGACGCCATGAAGGCCACGCT
CGACACGTTCGGCCGCGTCGACGGCTGCTTCGCGAATGCCGGCATCGGCGGCGGCGGCCGCAAGCCCTTCATCGAGCGCA
GCGAGGAAGAGTGGCGCACGATGTTCGCGACCAATCTCGACGGCGTCTTCCACGCCTTCCAGGCCGCCGCCAGGCACATG
ACTGCGCGCGCCGAAGCCGGCGATGCGTTCGGCCGGCTGGTTGCGACATCAAGCCTCGCCTCGCTTTTCGGCACCGCGCG
CAACGAGCACTATGCGGCGACCAAGGCCGCCATCAACGCGCTGTGCCGTGCGCTGGCGGTCGAGCTCGCCCGCTACGGCG
TGACGGCCAATGCGATCCTGCCAGGCTGGATCAAGAGCGACATGACGGCGGGCATCATGGGCAACGAGAAGTTCGTCGCC
AACGTGATGCCGCGCATTCCGGTGCGCCGCTTCGGCGAGCCGTCGGATTTCGGCGGCATCGCCGTCTACCTGATGAGCAA
GGCGTCGTCCTACCACACAGCCGACTGGTTTGTGATCGACGGCGGCTATACCGCGTTCTGA

Upstream 100 bases:

>100_bases
GTGCTTGAATTGCATGGTTTCCTCTCAAGAGCTGTTCGGGCGCTGCATTCTTCGCGGCGGAAATTCGCAAGTTTGCCGGT
GCGTGCAGCATATTTGATTT

Downstream 100 bases:

>100_bases
TCTGCAGCGACGGACAGTGGACCGGCGCGCCGGTCCACGAAACCCGGCTTTGTTCCACTCCTCTATTCCAAGATTTCCGA
AATTTAATCAGCCACGTGCT

Product: putative reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRFACPWLRHPNNGSDAQRPHIITETLMTPFDLTGRVAVVTGGNGGIGLGIAQALASSGCNVSIWGRNTEKNKAAAASMA
AGPGKVDTRICDVTSPASVADAMKATLDTFGRVDGCFANAGIGGGGRKPFIERSEEEWRTMFATNLDGVFHAFQAAARHM
TARAEAGDAFGRLVATSSLASLFGTARNEHYAATKAAINALCRALAVELARYGVTANAILPGWIKSDMTAGIMGNEKFVA
NVMPRIPVRRFGEPSDFGGIAVYLMSKASSYHTADWFVIDGGYTAF

Sequences:

>Translated_286_residues
MRFACPWLRHPNNGSDAQRPHIITETLMTPFDLTGRVAVVTGGNGGIGLGIAQALASSGCNVSIWGRNTEKNKAAAASMA
AGPGKVDTRICDVTSPASVADAMKATLDTFGRVDGCFANAGIGGGGRKPFIERSEEEWRTMFATNLDGVFHAFQAAARHM
TARAEAGDAFGRLVATSSLASLFGTARNEHYAATKAAINALCRALAVELARYGVTANAILPGWIKSDMTAGIMGNEKFVA
NVMPRIPVRRFGEPSDFGGIAVYLMSKASSYHTADWFVIDGGYTAF
>Mature_286_residues
MRFACPWLRHPNNGSDAQRPHIITETLMTPFDLTGRVAVVTGGNGGIGLGIAQALASSGCNVSIWGRNTEKNKAAAASMA
AGPGKVDTRICDVTSPASVADAMKATLDTFGRVDGCFANAGIGGGGRKPFIERSEEEWRTMFATNLDGVFHAFQAAARHM
TARAEAGDAFGRLVATSSLASLFGTARNEHYAATKAAINALCRALAVELARYGVTANAILPGWIKSDMTAGIMGNEKFVA
NVMPRIPVRRFGEPSDFGGIAVYLMSKASSYHTADWFVIDGGYTAF

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=29.8507462686567, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=31.0483870967742, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=29.0076335877863, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=27.3076923076923, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=28.515625, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=27.4509803921569, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=28.0769230769231, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504505, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718074, Length=215, Percent_Identity=31.1627906976744, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=262, Percent_Identity=26.3358778625954, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI209862901, Length=215, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19923983, Length=215, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=32.5396825396825, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=32.6996197718631, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=34.7490347490347, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.3172690763052, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=31.9066147859922, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=28, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=27.0992366412214, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=296, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=270, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786701, Length=207, Percent_Identity=32.3671497584541, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=31.7460317460317, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=26.4822134387352, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=29.4776119402985, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=31.5589353612167, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=28.5185185185185, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.9245283018868, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.7878787878788, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=26.1194029850746, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=28.6792452830189, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=27.7153558052434, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.1698113207547, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=226, Percent_Identity=30.5309734513274, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=28.6764705882353, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=28.1481481481481, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=25.9259259259259, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=27.1375464684015, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=25, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=25.1968503937008, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=25.6603773584906, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=25.4681647940075, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=24.8148148148148, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=26.0536398467433, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=24.5353159851301, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=24.5210727969349, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=254, Percent_Identity=28.740157480315, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=266, Percent_Identity=31.203007518797, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322861, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=31.1284046692607, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=27.2373540856031, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=28.8537549407115, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=31.1284046692607, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=29.9610894941634, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640492, Length=217, Percent_Identity=27.6497695852535, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI18859837, Length=210, Percent_Identity=30.4761904761905, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=27.5471698113208, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=28.5106382978723, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356301, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30188; Mature: 30188

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFACPWLRHPNNGSDAQRPHIITETLMTPFDLTGRVAVVTGGNGGIGLGIAQALASSGC
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
NVSIWGRNTEKNKAAAASMAAGPGKVDTRICDVTSPASVADAMKATLDTFGRVDGCFANA
EEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEECC
GIGGGGRKPFIERSEEEWRTMFATNLDGVFHAFQAAARHMTARAEAGDAFGRLVATSSLA
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFGTARNEHYAATKAAINALCRALAVELARYGVTANAILPGWIKSDMTAGIMGNEKFVA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHH
NVMPRIPVRRFGEPSDFGGIAVYLMSKASSYHTADWFVIDGGYTAF
HCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCEECC
>Mature Secondary Structure
MRFACPWLRHPNNGSDAQRPHIITETLMTPFDLTGRVAVVTGGNGGIGLGIAQALASSGC
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
NVSIWGRNTEKNKAAAASMAAGPGKVDTRICDVTSPASVADAMKATLDTFGRVDGCFANA
EEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEECC
GIGGGGRKPFIERSEEEWRTMFATNLDGVFHAFQAAARHMTARAEAGDAFGRLVATSSLA
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFGTARNEHYAATKAAINALCRALAVELARYGVTANAILPGWIKSDMTAGIMGNEKFVA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHH
NVMPRIPVRRFGEPSDFGGIAVYLMSKASSYHTADWFVIDGGYTAF
HCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]