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The map label for this gene is fabA [H]

Identifier: 146339383

GI number: 146339383

Start: 2521069

End: 2521593

Strand: Reverse

Name: fabA [H]

Synonym: BRADO2366

Alternate gene names: 146339383

Gene position: 2521593-2521069 (Counterclockwise)

Preceding gene: 146339384

Following gene: 146339369

Centisome position: 33.82

GC content: 67.05

Gene sequence:

>525_bases
TTGCCCGATCCCCGCGACTTTCACGTGCCGCAATCGTCCTACAGCAAGCAGGATCTGCTTCGCTCCAGTGAGGGCGGCTA
TTTCGGGCCGGGCAACGCGCAGCTGCCGGCGCCGCCGATGCTGATGATGGACCGAATCACCGAATTGAGCCTGGACGGCG
GCCGCTATGGCAAGGGGCGCATCGTCGCCGAGTTGGACATCACGCCGAAGCTCTGGTTCTTCGACTGCCTGTTCCGCGGC
GATCCCGTGATGCCGGGCTGTCTCGGCCTCGACGCGATGTGGCAGATGGTGGGCTATTGGCTCGGCTGGTCGGGCTCGCC
CGGCAAGGGCCGCGCCACCGGTGTCGGCGAGGTGAGCTTTCGCGGCGAGATCACGCCGGAGGTGAGTTGCGTGCGCTATG
AGGTCGACATGCGCCAGGTCCGCCGCGGCCGCCTCGTGCTCGGCCTCGCTGATGGACGCGTGCTCGCGGACGACCGCTGC
GTCTATGAAGCGCGGGACATGAAGGTGGCGCTGACGACAGCATGA

Upstream 100 bases:

>100_bases
CACGCTCAGCTATTTCGCTGCGGTCGCTTGAAGCATCGGCACTGCACTCCCATCCTTTAGCCGCGGAACCGCCGCCGATG
GCAGAACCGGAGATGATGCC

Downstream 100 bases:

>100_bases
CAATCGATGCTGTCATGATAGACGCTTCTCGAAGAACAGGTCCGGATAGGGATCGTCGTTGAAGCGGTCGATCTCGGTCC
ATCCGGTGGCGCGATAGAGC

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MPDPRDFHVPQSSYSKQDLLRSSEGGYFGPGNAQLPAPPMLMMDRITELSLDGGRYGKGRIVAELDITPKLWFFDCLFRG
DPVMPGCLGLDAMWQMVGYWLGWSGSPGKGRATGVGEVSFRGEITPEVSCVRYEVDMRQVRRGRLVLGLADGRVLADDRC
VYEARDMKVALTTA

Sequences:

>Translated_174_residues
MPDPRDFHVPQSSYSKQDLLRSSEGGYFGPGNAQLPAPPMLMMDRITELSLDGGRYGKGRIVAELDITPKLWFFDCLFRG
DPVMPGCLGLDAMWQMVGYWLGWSGSPGKGRATGVGEVSFRGEITPEVSCVRYEVDMRQVRRGRLVLGLADGRVLADDRC
VYEARDMKVALTTA
>Mature_173_residues
PDPRDFHVPQSSYSKQDLLRSSEGGYFGPGNAQLPAPPMLMMDRITELSLDGGRYGKGRIVAELDITPKLWFFDCLFRGD
PVMPGCLGLDAMWQMVGYWLGWSGSPGKGRATGVGEVSFRGEITPEVSCVRYEVDMRQVRRGRLVLGLADGRVLADDRCV
YEARDMKVALTTA

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=161, Percent_Identity=56.5217391304348, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19267; Mature: 19136

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPRDFHVPQSSYSKQDLLRSSEGGYFGPGNAQLPAPPMLMMDRITELSLDGGRYGKGR
CCCCCCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHEECCCCCCCCCE
IVAELDITPKLWFFDCLFRGDPVMPGCLGLDAMWQMVGYWLGWSGSPGKGRATGVGEVSF
EEEEEECCCCCEEEEHHHCCCCCCCCHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
RGEITPEVSCVRYEVDMRQVRRGRLVLGLADGRVLADDRCVYEARDMKVALTTA
CCCCCCCEEEEEEECCHHHHCCCCEEEEECCCEEEECCCEEEECCCEEEEEECC
>Mature Secondary Structure 
PDPRDFHVPQSSYSKQDLLRSSEGGYFGPGNAQLPAPPMLMMDRITELSLDGGRYGKGR
CCCCCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHEECCCCCCCCCE
IVAELDITPKLWFFDCLFRGDPVMPGCLGLDAMWQMVGYWLGWSGSPGKGRATGVGEVSF
EEEEEECCCCCEEEEHHHCCCCCCCCHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
RGEITPEVSCVRYEVDMRQVRRGRLVLGLADGRVLADDRCVYEARDMKVALTTA
CCCCCCCEEEEEEECCHHHHCCCCEEEEECCCEEEECCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA