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The map label for this gene is slt [C]

Identifier: 146339252

GI number: 146339252

Start: 2368444

End: 2369148

Strand: Direct

Name: slt [C]

Synonym: BRADO2222

Alternate gene names: 146339252

Gene position: 2368444-2369148 (Clockwise)

Preceding gene: 146339251

Following gene: 146339254

Centisome position: 31.76

GC content: 65.53

Gene sequence:

>705_bases
ATGCTCGACAACGAATCCGACAGTGAGATTCCGCCGCTGCAGCTCGAGCGCTTCGCCCCCAGGCCCTTGTCGGCCGCGGA
CCTGCCGCCCGCTAGCCCGTTCGCGCGCGGGGCGACGAGCCGCGGTCTGCGTGCGACCAGCATGATCCTGCCGCGGGACT
GGCGCGCACAACGTTCCGAGTACCGCGACTTGATCGAGCGTGAGGCATCAGCGGAAGGGGTGCCGCCGGCCATCGTCGAT
GCGGTCATGGCCGTCGAGAGCAGCTATGTTCCGACGGTGGTCGGACTTGATGGCGAGATCGGCCTGATGCAGGTCATGCC
CTCAACCGCGCGCATGCTTGGCTTCACCGGGACGGCCGAGCAGCTTGCGGACCCCGCGGCGAACATCCGTTACGGCACCA
AATATCTGGCGGGCGCGTGGCGTCTCGCGGGTGGCGACCTCTGTACCGCCGCCATGAAATATCGGGCCGGTCACGGCGAG
ACACGCTTTTCATATTTGTCGATTGCCTATTGCCTGCGAATTCGCAGTCACCTCGCCGCGCAGGGCGTCCAGGTCTCAGG
AGACGTGCCGCAGGCGACCTTTGGACGCTCCGTCGCCACAGCGCGCACAGATGCATCCGTATCGGGGCGTCCGCTCGACA
TCGTTTCCCTGAACATGAAGCTCCACGTCCTGACACGCCGTAACGCGGACAGAGCTGCGCCATAA

Upstream 100 bases:

>100_bases
GGTTGCCGCGACTGGTTTCGGTGTGTTGCTCGGTGCGGCGGCCGGCGCGTTAGCCCTAGCGAGTGAGGCGGAGCGGGCGG
AGGATAGCCCGGCCGCGAGC

Downstream 100 bases:

>100_bases
TCAGCCGTACGATGTGGGACGGCCTTGCCGCAGCAACGCGTGCTCACGTCCGAAAGAAGATCCTTGGGGCGGGGGGAGAG
CGGCGATCCGTCGCGGTTTG

Product: transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Transglycosylase Protein; Soluble Lytic Transglycosylase; Lytic Transglycosylase; Peptide Deformylase; Transmembrane Protein; Transglycosylase SLT Domain Protein; Transglycosylase Signal Peptide Protein; Soluble Lytic Murein Transglycosylase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLDNESDSEIPPLQLERFAPRPLSAADLPPASPFARGATSRGLRATSMILPRDWRAQRSEYRDLIEREASAEGVPPAIVD
AVMAVESSYVPTVVGLDGEIGLMQVMPSTARMLGFTGTAEQLADPAANIRYGTKYLAGAWRLAGGDLCTAAMKYRAGHGE
TRFSYLSIAYCLRIRSHLAAQGVQVSGDVPQATFGRSVATARTDASVSGRPLDIVSLNMKLHVLTRRNADRAAP

Sequences:

>Translated_234_residues
MLDNESDSEIPPLQLERFAPRPLSAADLPPASPFARGATSRGLRATSMILPRDWRAQRSEYRDLIEREASAEGVPPAIVD
AVMAVESSYVPTVVGLDGEIGLMQVMPSTARMLGFTGTAEQLADPAANIRYGTKYLAGAWRLAGGDLCTAAMKYRAGHGE
TRFSYLSIAYCLRIRSHLAAQGVQVSGDVPQATFGRSVATARTDASVSGRPLDIVSLNMKLHVLTRRNADRAAP
>Mature_234_residues
MLDNESDSEIPPLQLERFAPRPLSAADLPPASPFARGATSRGLRATSMILPRDWRAQRSEYRDLIEREASAEGVPPAIVD
AVMAVESSYVPTVVGLDGEIGLMQVMPSTARMLGFTGTAEQLADPAANIRYGTKYLAGAWRLAGGDLCTAAMKYRAGHGE
TRFSYLSIAYCLRIRSHLAAQGVQVSGDVPQATFGRSVATARTDASVSGRPLDIVSLNMKLHVLTRRNADRAAP

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082441, Length=108, Percent_Identity=35.1851851851852, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 25144; Mature: 25144

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNESDSEIPPLQLERFAPRPLSAADLPPASPFARGATSRGLRATSMILPRDWRAQRSE
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCEEHEEECCCHHHHHHHH
YRDLIEREASAEGVPPAIVDAVMAVESSYVPTVVGLDGEIGLMQVMPSTARMLGFTGTAE
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCHHHHHHCCCCCHH
QLADPAANIRYGTKYLAGAWRLAGGDLCTAAMKYRAGHGETRFSYLSIAYCLRIRSHLAA
HHHCCHHCCCCCHHHHHHHHEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QGVQVSGDVPQATFGRSVATARTDASVSGRPLDIVSLNMKLHVLTRRNADRAAP
CCEEECCCCCCHHHCCCHHHCCCCCCCCCCCEEEEEECEEEEEEEECCCCCCCC
>Mature Secondary Structure
MLDNESDSEIPPLQLERFAPRPLSAADLPPASPFARGATSRGLRATSMILPRDWRAQRSE
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCEEHEEECCCHHHHHHHH
YRDLIEREASAEGVPPAIVDAVMAVESSYVPTVVGLDGEIGLMQVMPSTARMLGFTGTAE
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCHHHHHHCCCCCHH
QLADPAANIRYGTKYLAGAWRLAGGDLCTAAMKYRAGHGETRFSYLSIAYCLRIRSHLAA
HHHCCHHCCCCCHHHHHHHHEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QGVQVSGDVPQATFGRSVATARTDASVSGRPLDIVSLNMKLHVLTRRNADRAAP
CCEEECCCCCCHHHCCCHHHCCCCCCCCCCCEEEEEECEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA